Characterization of the CIN85 adaptor protein and identification of components involved in CIN85 complexes
about
Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1A novel proteomic screen for peptide-protein interactionsCIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinasesThe B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptorsCbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors.The role of the ubiquitination-proteasome pathway in breast cancer: ubiquitin mediated degradation of growth factor receptors in the pathogenesis and treatment of cancerMembrane trafficking in podocyte health and diseaseThe adaptor protein CIN85 assembles intracellular signaling clusters for B cell activationYeast Npi3/Bro1 is involved in ubiquitin-dependent control of permease trafficking.Linking the T cell surface protein CD2 to the actin-capping protein CAPZ via CMS and CIN85Ruk is ubiquitinated but not degraded by the proteasomeThe Cbl interactome and its functionsIdentification and characterization of a novel Rho GTPase activating protein implicated in receptor-mediated endocytosisSH3KBP1-binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complexGrb2 carboxyl-terminal SH3 domain can bivalently associate with two ligands, in an SH3 dependent manner.Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3).CIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface.Structure of the kidney slit diaphragm adapter protein CD2-associated protein as determined with electron microscopy.Dab1-mediated colocalization of multi-adaptor protein CIN85 with Reelin receptors, ApoER2 and VLDLR, in neurons.CIN85 interacting proteins in B cells-specific role for SHIP-1.Cbl promotes clustering of endocytic adaptor proteins.Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors.Atypical recognition consensus of CIN85/SETA/Ruk SH3 domains revealed by target-assisted iterative screening.Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalizationCIN85/CMS family of adaptor molecules.Network-Based Integration of Disparate Omic Data To Identify "Silent Players" in CancerDynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity.The basic amino acids in the coiled-coil domain of CIN85 regulate its interaction with c-Cbl and phosphatidic acid during epidermal growth factor receptor (EGFR) endocytosis.Scaffolding of antigen receptors for immunogenic versus tolerogenic signaling.CD2AP regulates SUMOylation of CIN85 in podocytes.Alix/AIP1 antagonizes epidermal growth factor receptor downregulation by the Cbl-SETA/CIN85 complex.Endocytic Trafficking at the Mature Podocyte Slit Diaphragm.C-terminal domains implicated in the functional surface expression of potassium channels.CIN85 drives B cell responses by linking BCR signals to the canonical NF-kappaB pathway.The binding stoichiometry of CIN85 SH3 domain A and cbl-b.p-6Y-SYK phosphorylates BLNK (SLP65)CD2AP/CIN85 balance determines receptor tyrosine kinase signaling response in podocytes.Identification and characterisation of a Theileria annulata proline-rich microtubule and SH3 domain-interacting protein (TaMISHIP) that forms a complex with CLASP1, EB1, and CD2AP at the schizont surface.Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins To Regulate Epidermal Growth Factor Receptor and Reactivation from Latency
P2860
Q24298086-F6DF6611-B255-4CFD-A497-8339311E102AQ24302054-004313E7-DA0E-490F-9FDE-481CA835CF76Q24304461-C7E1F332-CF87-4B2F-9D51-599569566C2BQ24319764-9019D942-7C57-49F5-8CD1-D8555A852056Q24337144-52FF0D7E-D7B2-46EF-AEE6-E56A5E5A3BD7Q24535794-B64FB66D-7873-418C-AD41-1841EE7D373CQ24794951-219BBE5F-899B-4A70-9E38-6996A37E7877Q27015885-E9F6F9FE-C338-429B-9993-E893657C4506Q27714533-789C7871-CF76-421F-9565-9E37EDAA5C9DQ27940285-D7A6AA52-5B1D-4704-AA0C-C9B923DD7C18Q28190350-E4CCEAF9-A16B-4615-B7A0-41AC5FB7740BQ28215630-303DCBDA-C9B6-4251-8E15-34D766060BDCQ28277251-5EF7527B-AD16-4F7D-89C2-2D2864EAC061Q28571750-E08BFE55-E82E-4F6D-AF5E-19C5B5419AACQ28588117-F5AD02BA-1078-43E6-887E-8DE5FAB22958Q30008738-F0F93CA5-0A4E-463D-A70B-9EBCC8B5D5BDQ30009116-60AE38CA-E65A-4D2F-921E-BF1D8AEAAB2DQ30009137-3C4383B6-0FE3-4A2D-A86D-B51B7DF35B6BQ30009462-0DD30871-B883-4CCC-A6BF-E18CA8BD7FA5Q30009897-69EF92EE-C922-42B1-A2B5-F67D276640F4Q30010282-22CD83AE-EE34-4667-9CC6-4BF2AEFF97FCQ30160108-0B063466-C0B5-4C21-93A6-DCC9BD32E4FEQ30164615-B868DE8A-AE60-4DE1-80F9-65562BE11474Q30164651-13AACA6B-B01C-45B5-A8B7-11EE1328B320Q30164745-A07AD7EF-5722-43DA-B61F-A51B975D2F6AQ30165181-A1703BE9-3453-4FF5-A298-DCCDD07A067AQ31032861-0CE1D6A7-D656-4CB9-9231-6E2CEF13D5D5Q33877069-C4DCD6FF-D438-45FF-A96A-AE00C33615ACQ33895325-598E8EE1-1C74-4300-A501-8C959171A508Q35571851-7644767F-5235-4582-82CA-5C57084D1F30Q35806658-057CEA01-CB47-4AFD-A55D-3A1DD6418750Q37527117-4F256640-C1E5-4E5B-883D-4C920AA9EC12Q37662983-F4F98330-2E0A-4261-B40C-7DD70B4FBA5EQ39698879-7A30F30F-D8B4-4E4A-8C64-5E312F55DBA0Q41789207-24D02FE6-86F6-4A4F-B64E-DD26EF09EE4AQ42601055-22159D30-79D5-40C1-B67E-F5F3EFDF9441Q50291475-60F67B74-9FDA-4368-88D7-79CF07FA0F64Q53578450-F2B00A59-BBE8-4955-BE2E-92B69212A557Q53703513-8A5E9603-D81A-4C41-BFAA-A05077B2F281Q57469888-55DF7FEE-9888-4033-B865-A254DB9A06C2
P2860
Characterization of the CIN85 adaptor protein and identification of components involved in CIN85 complexes
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Characterization of the CIN85 ...... ts involved in CIN85 complexes
@ast
Characterization of the CIN85 ...... ts involved in CIN85 complexes
@en
Characterization of the CIN85 ...... ts involved in CIN85 complexes
@nl
type
label
Characterization of the CIN85 ...... ts involved in CIN85 complexes
@ast
Characterization of the CIN85 ...... ts involved in CIN85 complexes
@en
Characterization of the CIN85 ...... ts involved in CIN85 complexes
@nl
prefLabel
Characterization of the CIN85 ...... ts involved in CIN85 complexes
@ast
Characterization of the CIN85 ...... ts involved in CIN85 complexes
@en
Characterization of the CIN85 ...... ts involved in CIN85 complexes
@nl
P2093
P356
P1476
Characterization of the CIN85 ...... ts involved in CIN85 complexes
@en
P2093
P304
P356
10.1006/BBRC.2000.3760
P407
P577
2000-11-11T00:00:00Z