CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases - Wikidata - wikimedia - TriplyDB

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

http://www.wikidata.org/entity/Q24304461

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CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery Dab2 links CIN85 with clathrin-mediated receptor internalization Atypical polyproline recognition by the CMS N-terminal Src homology 3 domain Identification and functional characterization of an Src homology domain 3 domain-binding site on Cbl CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors The BAR domain proteins: molding membranes in fission, fusion, and phagy A tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulation Functional diversity and structural disorder in the human ubiquitination pathway Distinct Ubiquitin Binding Modes Exhibited by SH3 Domains: Molecular Determinants and Functional Implications The Rsp5 ubiquitin ligase binds to and ubiquitinates members of the yeast CIN85-endophilin complex, Sla1-Rvs167.Phosphorylation of human tristetraprolin in response to its interaction with the Cbl interacting protein CIN85 SH3KBP1-binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complex CIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface.Hepatitis C virus NS5A protein blocks epidermal growth factor receptor degradation via a proline motif- dependent interaction Structure of the kidney slit diaphragm adapter protein CD2-associated protein as determined with electron microscopy.CD2-associated protein (CD2AP) enhances casitas B lineage lymphoma-3/c (Cbl-3/c)-mediated Ret isoform-specific ubiquitination and degradation via its amino-terminal Src homology 3 domains.Dab1-mediated colocalization of multi-adaptor protein CIN85 with Reelin receptors, ApoER2 and VLDLR, in neurons.CIN85 interacting proteins in B cells-specific role for SHIP-1.ARAP1 association with CIN85 affects epidermal growth factor receptor endocytic trafficking The interactome of a PTB domain-containing adapter protein, Odin, revealed by SILAC Cbl promotes clustering of endocytic adaptor proteins.Src phosphorylation of Alix/AIP1 modulates its interaction with binding partners and antagonizes its activities Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases.Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors.Atypical recognition consensus of CIN85/SETA/Ruk SH3 domains revealed by target-assisted iterative screening.Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization Adaptor protein Ruk/CIN85 is associated with a subset of COPI-coated membranes of the Golgi complex.The basic amino acids in the coiled-coil domain of CIN85 regulate its interaction with c-Cbl and phosphatidic acid during epidermal growth factor receptor (EGFR) endocytosis.E3 ubiquitin ligase Cbl-b in innate and adaptive immunity.Novel oncogenic mutations of CBL in human acute myeloid leukemia that activate growth and survival pathways depend on increased metabolism Actin and endocytosis in budding yeast.Endocytosis and intracellular trafficking of ErbBs.Complex of MUC1, CIN85 and Cbl in Colon Cancer Progression and Metastasis.Cargo- and compartment-selective endocytic scaffold proteins.Endocytosis of receptor tyrosine kinases SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling.Essential role of c-Cbl in amphiregulin-induced recycling and signaling of the endogenous epidermal growth factor receptor Loss of Cbl-b increases osteoclast bone-resorbing activity and induces osteopenia.Ubiquitin ligase Cbl-b is a negative regulator for insulin-like growth factor 1 signaling during muscle atrophy caused by unloading.Intermolecular interactions of Sprouty proteins and their implications in development and disease.

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CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

http://www.wikidata.org/entity/Q24304461

description

2002 nî lūn-bûn

@nan

2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

@ast

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

@en

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

@en-gb

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

@nl

type

label

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

@ast

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

@en

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

@en-gb

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

@nl

prefLabel

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

@ast

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

@en

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

@en-gb

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

@nl

P1433

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P1476

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P356

P1433

Journal of Biological Chemistry

P1476

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

@en

P2093

Ana Dinarina

http://www.w3.org/2001/XMLSchema#string

Iwona Szymkiewicz

http://www.w3.org/2001/XMLSchema#string

Katarzyna Kowanetz

http://www.w3.org/2001/XMLSchema#string

Stanley Lipkowitz

http://www.w3.org/2001/XMLSchema#string

P2860

cbl-3: a new mammalian cbl family protein

Cloning and characterization of a novel adaptor protein, CIN85, that interacts with c-Cbl

Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility

Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10

Negative regulation of PI 3-kinase by Ruk, a novel adaptor protein

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes

Hrs interacts with sorting nexin 1 and regulates degradation of epidermal growth factor receptor

Biochemistry. Ubiquitination--more than two to tango

SETA is a multifunctional adapter protein with three SH3 domains that binds Grb2, Cbl, and the novel SB1 proteins

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39666-72

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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10.1074/JBC.M205535200

http://www.w3.org/2001/XMLSchema#string

P407

P433

42

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277

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Philippe Soubeyran

P577

2002-10-18T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

12177062

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