beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation
about
Dishevelled and Wnt signaling: is the nucleus the final frontier?beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteinsCK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signalingRegulation of the discs large tumor suppressor by a phosphorylation-dependent interaction with the beta-TrCP ubiquitin ligase receptorBeta-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletionNedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalphaShared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members.Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancerWnt signaling: the good and the badNr-CAM is a target gene of the beta-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesisNuclear localization is required for Dishevelled function in Wnt/beta-catenin signalingMolecular specification of germ layers in vertebrate embryosThe many faces and functions of β-cateninPeptide-in-groove interactions link target proteins to the beta-propeller of clathrinERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer DevelopmentDifferential interaction of plakoglobin and beta-catenin with the ubiquitin-proteasome systemAxin-dependent phosphorylation of the adenomatous polyposis coli protein mediated by casein kinase 1epsilonThe β-catenin destruction complexCustos controls β-catenin to regulate head development during vertebrate embryogenesisWnt signals are transmitted through N-terminally dephosphorylated beta-cateninF-box protein FBXL2 targets cyclin D2 for ubiquitination and degradation to inhibit leukemic cell proliferationCalmodulin protects Aurora B on the midbody to regulate the fidelity of cytokinesis.F-box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrestInteraction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction.Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factorRepurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposisSox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleusProlyl isomerase Pin1 regulates neuronal differentiation via β-cateninMouse homologue of HOS (mHOS) is overexpressed in skin tumors and implicated in constitutive activation of NF-kappaBDishevelled-3 C-terminal His single amino acid repeats are obligate for Wnt5a activation of non-canonical signalingMutation of Vav1 adaptor region reveals a new oncogenic activation.Associations Among -TrCP, an E3 Ubiquitin Ligase Receptor, -Catenin, and NF- B in Colorectal CancerDeregulation of F-box proteins and its consequence on cancer development, progression and metastasis.Beta-catenin regulation during the cell cycle: implications in G2/M and apoptosisComplete functional segregation of planarian beta-catenin-1 and -2 in mediating Wnt signaling and cell adhesion.CCL2 disrupts the adherens junction: implications for neuroinflammationAccumulation of phosphorylated beta-catenin enhances ROS-induced cell death in presenilin-deficient cellsInhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6.Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in Wnt-dependent manner.Crumbs promotes expanded recognition and degradation by the SCF(Slimb/β-TrCP) ubiquitin ligase
P2860
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P2860
beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
beta-Trcp couples beta-catenin ...... gulates Xenopus axis formation
@ast
beta-Trcp couples beta-catenin ...... gulates Xenopus axis formation
@en
beta-Trcp couples beta-catenin ...... gulates Xenopus axis formation
@nl
type
label
beta-Trcp couples beta-catenin ...... gulates Xenopus axis formation
@ast
beta-Trcp couples beta-catenin ...... gulates Xenopus axis formation
@en
beta-Trcp couples beta-catenin ...... gulates Xenopus axis formation
@nl
prefLabel
beta-Trcp couples beta-catenin ...... gulates Xenopus axis formation
@ast
beta-Trcp couples beta-catenin ...... gulates Xenopus axis formation
@en
beta-Trcp couples beta-catenin ...... gulates Xenopus axis formation
@nl
P2093
P2860
P356
P1476
beta-Trcp couples beta-catenin ...... gulates Xenopus axis formation
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.11.6273
P407
P577
1999-05-25T00:00:00Z