Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis
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The Role of Hedgehog Signaling in Tumor Induced Bone DiseaseCooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapyArsenic Attenuates GLI Signaling, Increasing or Decreasing its Transcriptional Program in a Context-Dependent Manner.Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respirationTargeting of Wnt/β-Catenin by Anthelmintic Drug Pyrvinium Enhances Sensitivity of Ovarian Cancer Cells to Chemotherapy.The novel role of pyrvinium in cancer therapy.Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.The role of Pygo2 for Wnt/ß-catenin signaling activity during intestinal tumor initiation and progression.Targeting the Wnt/beta-catenin pathway in cancer: Update on effectors and inhibitors.Pharmacologic Inhibition of β-Catenin With Pyrvinium Inhibits Murine and Human Models of Wilms Tumor.Complex HuR function in pancreatic cancer cells.Anthelmintic pyrvinium pamoate blocks Wnt/β-catenin and induces apoptosis in multiple myeloma cells.Casein kinase 1α: biological mechanisms and theranostic potential.
P2860
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P2860
Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis
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2014 nî lūn-bûn
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2014 թուականին հրատարակուած գիտական յօդուած
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2014 թվականին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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Repurposing the FDA-approved p ...... agent for intestinal polyposis
@ast
Repurposing the FDA-approved p ...... agent for intestinal polyposis
@en
Repurposing the FDA-approved p ...... agent for intestinal polyposis
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label
Repurposing the FDA-approved p ...... agent for intestinal polyposis
@ast
Repurposing the FDA-approved p ...... agent for intestinal polyposis
@en
Repurposing the FDA-approved p ...... agent for intestinal polyposis
@nl
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Repurposing the FDA-approved p ...... agent for intestinal polyposis
@ast
Repurposing the FDA-approved p ...... agent for intestinal polyposis
@en
Repurposing the FDA-approved p ...... agent for intestinal polyposis
@nl
P2093
P2860
P1433
P1476
Repurposing the FDA-approved p ...... agent for intestinal polyposis
@en
P2093
Anthony J Capobianco
Brian I Hang
Camilla Giambelli
Colin A Flaveny
Darren Orton
David J Robbins
Dennis Liang Fei
P2860
P304
P356
10.1371/JOURNAL.PONE.0101969
P407
P577
2014-07-08T00:00:00Z