Expression and function of the mouse collagen receptor glycoprotein VI is strictly dependent on its association with the FcRgamma chain
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The tyrosine phosphatase 1B regulates linker for activation of T-cell phosphorylation and platelet aggregation upon FcgammaRIIa cross-linkingPlatelets amplify inflammation in arthritis via collagen-dependent microparticle productionGlycoprotein VI-dependent and -independent pathways of thrombus formation in vivoA PLC gamma 2-independent platelet collagen aggregation requiring functional association of GPVI and integrin alpha2beta1Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen.Zinc oxide nanoparticles-induced epigenetic change and G2/M arrest are associated with apoptosis in human epidermal keratinocytesPlatelet biogenesis and functions require correct protein O-glycosylationGray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice.Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet functionG6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2RhoG protein regulates glycoprotein VI-Fc receptor γ-chain complex-mediated platelet activation and thrombus formationInflammation induces hemorrhage in thrombocytopenia.Synergism between platelet collagen receptors defined using receptor-specific collagen-mimetic peptide substrata in flowing blood.High-content live-cell imaging assay used to establish mechanism of trastuzumab emtansine (T-DM1)--mediated inhibition of platelet production.A role for adhesion and degranulation-promoting adapter protein in collagen-induced platelet activation mediated via integrin α(2) β(1)Evidence for two distinct epitopes within collagen for activation of murine platelets.Hematopoietic lineage cell specific protein 1 (HS1) is a functionally important signaling molecule in platelet activation.Platelet ITAM signaling is critical for vascular integrity in inflammation.Role of phosphoinositide 3-kinase beta in glycoprotein VI-mediated Akt activation in platelets.Targeting GPVI as a novel antithrombotic strategy.Platelet recruitment to the inflamed glomerulus occurs via an alphaIIbbeta3/GPVI-dependent pathway.CEACAM2 negatively regulates hemi (ITAM-bearing) GPVI and CLEC-2 pathways and thrombus growth in vitro and in vivo.The role of the adapter molecule SLP-76 in platelet function.α2β1 integrin, GPVI receptor, and common FcRγ chain on mouse platelets mediate distinct responses to collagen in models of thrombosisHyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikrein.Signaling events underlying thrombus formation.Both Fcgamma receptor I and Fcgamma receptor III mediate disease in accelerated nephrotoxic nephritisThe role of collagen in thrombosis and hemostasis.Role of FcRgamma and factor XIIIA in coated platelet formationA crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivoLong-term antithrombotic protection by in vivo depletion of platelet glycoprotein VI in mice.The Modifier of hemostasis (Mh) locus on chromosome 4 controls in vivo hemostasis of Gp6-/- mice.Platelet-derived CD154 enables T-cell priming and protection against Listeria monocytogenes challengePlatelet integrins and immunoreceptors.Identification of a major GpVI-binding locus in human type III collagen.Deficiency of the tetraspanin CD63 associated with kidney pathology but normal lysosomal functionPlatelets: developmental biology, physiology, and translatable platforms for preclinical investigation and drug development.Suboptimal activation of protease-activated receptors enhances alpha2beta1 integrin-mediated platelet adhesion to collagen.Platelet physiology and antiplatelet agents.Platelet adhesion and activation mechanisms in arterial thrombosis and ischaemic stroke.
P2860
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P2860
Expression and function of the mouse collagen receptor glycoprotein VI is strictly dependent on its association with the FcRgamma chain
description
2000 nî lūn-bûn
@nan
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Expression and function of the ...... iation with the FcRgamma chain
@ast
Expression and function of the ...... iation with the FcRgamma chain
@en
Expression and function of the ...... iation with the FcRgamma chain
@nl
type
label
Expression and function of the ...... iation with the FcRgamma chain
@ast
Expression and function of the ...... iation with the FcRgamma chain
@en
Expression and function of the ...... iation with the FcRgamma chain
@nl
prefLabel
Expression and function of the ...... iation with the FcRgamma chain
@ast
Expression and function of the ...... iation with the FcRgamma chain
@en
Expression and function of the ...... iation with the FcRgamma chain
@nl
P2093
P3181
P356
P1476
Expression and function of the ...... iation with the FcRgamma chain
@en
P2093
B Nieswandt
H Zirngibl
J E Gessner
K Rackebrandt
W Bergmeier
P304
23998-4002
P3181
P356
10.1074/JBC.M003803200
P407
P577
2000-08-04T00:00:00Z