A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo
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Aegyptin displays high-affinity for the von Willebrand factor binding site (RGQOGVMGF) in collagen and inhibits carotid thrombus formation in vivoDefective thrombus formation in mice lacking coagulation factor XIIGlycoprotein VI-dependent and -independent pathways of thrombus formation in vivoThe role of platelets in the recruitment of leukocytes during vascular diseaseNext-generation antithrombotics in ischemic stroke: preclinical perspective on 'bleeding-free antithrombosis'Anti-Inflammatory and Anti-Thrombotic Effects of the Fungal Metabolite Galiellalactone in Apolipoprotein E-Deficient MiceQuantification of the Blood Platelet Reactivity in the ADP-Induced Model of Non-Lethal Pulmonary Thromboembolism in Mice with the Use of Laser Doppler FlowmetryMolecular Imaging of Vulnerable Atherosclerotic Plaques in Animal Models.Leucocyte/endothelium interactions and microvessel permeability: coupled or uncoupled?The GPVI-Fc fusion protein Revacept reduces thrombus formation and improves vascular dysfunction in atherosclerosis without any impact on bleeding timesMultimodal optoacoustic and multiphoton microscopy of human carotid atheroma.Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation.Segregation of platelet aggregatory and procoagulant microdomains in thrombus formation: regulation by transient integrin activationThe calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction.Red blood cells mediate the onset of thrombosis in the ferric chloride murine model.A novel antiplatelet antibody therapy that induces cAMP-dependent endocytosis of the GPVI/Fc receptor gamma-chain complexPlatelet-associated IgAs and impaired GPVI responses in platelets lacking WIP.Proteolysis of platelet receptors in humans and other species.Structural and interaction analysis of glycoprotein VI-binding peptide selected from a phage display libraryTargeting GPVI as a novel antithrombotic strategy.Preoperative platelet response to collagen is associated with myocardial injury after off-pump coronary bypass graft in patients taking aspirin.Sustained reperfusion after blockade of glycoprotein-receptor-Ib in focal cerebral ischemia: an MRI study at 17.6 Tesla.Polymorphisms in the platelet-specific collagen receptor GP6 are associated with risk of nonfatal myocardial infarction in Caucasians.Aegyptin, a novel mosquito salivary gland protein, specifically binds to collagen and prevents its interaction with platelet glycoprotein VI, integrin alpha2beta1, and von Willebrand factorPlatelet recruitment to the inflamed glomerulus occurs via an alphaIIbbeta3/GPVI-dependent pathway.In vivo evidence for platelet-induced physiological angiogenesis by a COX driven mechanism.Shaping the platelet response to vascular injury.CEACAM2 negatively regulates hemi (ITAM-bearing) GPVI and CLEC-2 pathways and thrombus growth in vitro and in vivo.Fractalkine is expressed in early and advanced atherosclerotic lesions and supports monocyte recruitment via CX3CR1.Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.SLAP/SLAP2 prevent excessive platelet (hem)ITAM signaling in thrombosis and ischemic stroke in mice.The GPVI-Fc fusion protein Revacept improves cerebral infarct volume and functional outcome in strokePhosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators.Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosis.Perspective: Tyrosine phosphatases as novel targets for antiplatelet therapy.Bruton tyrosine kinase is essential for botrocetin/VWF-induced signaling and GPIb-dependent thrombus formation in vivo.Oral phenotype and scoring of vascular Ehlers-Danlos syndrome: a case-control study.Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo.Resolving the multifaceted mechanisms of the ferric chloride thrombosis model using an interdisciplinary microfluidic approach.Fibrin activates GPVI in human and mouse platelets
P2860
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P2860
A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
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2003年學術文章
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name
A crucial role of glycoprotein ...... injured arterial wall in vivo
@ast
A crucial role of glycoprotein ...... injured arterial wall in vivo
@en
type
label
A crucial role of glycoprotein ...... injured arterial wall in vivo
@ast
A crucial role of glycoprotein ...... injured arterial wall in vivo
@en
prefLabel
A crucial role of glycoprotein ...... injured arterial wall in vivo
@ast
A crucial role of glycoprotein ...... injured arterial wall in vivo
@en
P2093
P2860
P356
P1476
A crucial role of glycoprotein ...... injured arterial wall in vivo
@en
P2093
Bernhard Nieswandt
Dietlind Zohlnhöfer
Ildiko Konrad
Meinrad Gawaz
Sabine Grüner
Steffen Massberg
Ulrich Heinzmann
Valerie Schulte
P2860
P356
10.1084/JEM.20020945
P407
P577
2003-01-01T00:00:00Z