Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2
about
Human mitochondrial Hsp70 (mortalin): shedding light on ATPase activity, interaction with adenosine nucleotides, solution structure and domain organizationExtended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot-2 (mortalin)/mthsp70/Grp75.Differential proteome analysis of replicative senescence in rat embryo fibroblasts.Proproliferative functions of Drosophila small mitochondrial heat shock protein 22 in human cells.Protein homeostasis and aging: The importance of exquisite quality control.Targeting mortalin using conventional and RNA-helicase-coupled hammerhead ribozymesIdentifications small molecules inhibitor of p53-mortalin complex for cancer drug using virtual screening.An N-terminal region of mot-2 binds to p53 in vitro.An Hsp70 family chaperone, mortalin/mthsp70/PBP74/Grp75: what, when, and where?Molecular interactions of Bcl-2 and Bcl-xL with mortalin: identification and functional characterizationUbiquitin-like (UBX)-domain-containing protein, UBXN2A, promotes cell death by interfering with the p53-Mortalin interactions in colon cancer cellsRoles of reactive oxygen species in the fate of stem cells.Mortalin, apoptosis, and neurodegeneration.Serum from calorie-restricted animals delays senescence and extends the lifespan of normal human fibroblasts in vitro.Over-expression of GRP75 inhibits liver injury induced by oxidative damage.Identification and characterization of molecular interactions between mortalin/mtHsp70 and HSP60.Physiological and molecular assessment of altered expression of Hsc70-1 in Arabidopsis. Evidence for pleiotropic consequences.Quantum dot-based mortalin staining as a visual assay for detection of induced senescence in cancer cells.Structural and functional differences between mouse mot-1 and mot-2 proteins that differ in two amino acids.alpha-thrombin rapidly induces tyrosine phosphorylation of a novel, 74-78-kDa stress response protein(s) in lung fibroblast cells.Identification and characterization of molecular interactions between glucose-regulated proteins (GRPs) mortalin/GRP75/peptide-binding protein 74 (PBP74) and GRP94.Colocalisation of CD9 and mortalin in CD9-induced mitotic catastrophe in human prostate cancer cells.[RNA Interference targeting GRP75 decreases cisplatin resistance in human lung adenocarcinoma cell].An investigation of methyl tert‑butyl ether‑induced cytotoxicity and protein profile in Chinese hamster ovary cells.Mechanisms of protein homeostasis (proteostasis) maintain stem cell identity in mammalian pluripotent stem cells.
P2860
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P2860
Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2
@ast
Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2
@en
Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2
@nl
type
label
Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2
@ast
Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2
@en
Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2
@nl
prefLabel
Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2
@ast
Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2
@en
Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2
@nl
P2093
P2860
P1433
P1476
Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2
@en
P2093
R R Reddelb
T Sugiharac
P2860
P304
P356
10.1016/S0014-5793(00)01594-5
P407
P577
2000-06-02T00:00:00Z