Mammalian ASIC2a and ASIC3 subunits co-assemble into heteromeric proton-gated channels sensitive to Gd3+
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Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous systemcAMP-dependent protein kinase phosphorylation of the acid-sensing ion channel-1 regulates its binding to the protein interacting with C-kinase-1Molecular targets for antiepileptic drug developmentAcid-sensing ion channels in pain and disease.ASICs and cardiovascular homeostasisStructure and activity of the acid-sensing ion channelsCiliated neurons lining the central canal sense both fluid movement and pH through ASIC3.The PDZ domain protein PICK1 and the sodium channel BNaC1 interact and localize at mechanosensory terminals of dorsal root ganglion neurons and dendrites of central neuronsAcid-sensing ionic channels in the rat vestibular endorgans and gangliaIdentification of a mammalian H(+)-myo-inositol symporter expressed predominantly in the brain.Acid-sensing ion channel 2 (ASIC2) modulates ASIC1 H+-activated currents in hippocampal neuronsSubunit-specific inhibition of acid sensing ion channels by stomatin-like protein 1Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neuronsKnockout of the ASIC2 channel in mice does not impair cutaneous mechanosensation, visceral mechanonociception and hearingASIC2 subunits target acid-sensing ion channels to the synapse via an association with PSD-95The Concise Guide to PHARMACOLOGY 2013/14: ion channelsLocalization and behaviors in null mice suggest that ASIC1 and ASIC2 modulate responses to aversive stimuli.ASIC2 subunits facilitate expression at the cell surface and confer regulation by PSD-95.Acid-sensing ion channels in acidosis-induced injury of human brain neuronsAcid-sensing ion channels (ASICs): therapeutic targets for neurological diseases and their regulationASIC1 and ASIC3 play different roles in the development of Hyperalgesia after inflammatory muscle injury.Acid sensing ion channel 1 in lateral hypothalamus contributes to breathing controlGenetic models of mechanotransduction: the nematode Caenorhabditis elegans.ASIC3 channels in multimodal sensory perceptionGating of acid-sensitive ion channel-1: release of Ca2+ block vs. allosteric mechanism.Acid-Sensing Ion Channels Expression, Identity and Role in the Excitability of the Cochlear Afferent NeuronsSingle channel properties of rat acid-sensitive ion channel-1alpha, -2a, and -3 expressed in Xenopus oocytes.Single-channel properties of recombinant acid-sensitive ion channels formed by the subunits ASIC2 and ASIC3 from dorsal root ganglion neurons expressed in Xenopus oocytes.Two mechanisms involved in trigeminal CGRP release: implications for migraine treatment.Optogenetic approaches addressing extracellular modulation of neural excitability.TRPC5 channels participate in pressure-sensing in aortic baroreceptors.Two PKC consensus sites on human acid-sensing ion channel 1b differentially regulate its function.ASIC1 contributes to pulmonary vascular smooth muscle store-operated Ca(2+) entry.Enhanced muscle fatigue occurs in male but not female ASIC3-/- mice.A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons.ASIC2a-dependent increase of ASIC3 surface expression enhances the sustained component of the currents.Modulation of acid-sensing ion channels: molecular mechanisms and therapeutic potential.Acid-sensing ion channels contribute to neurotoxicity.Calcium-permeable ion channels in pain signaling.Proton-sensitive cation channels and ion exchangers in ischemic brain injury: new therapeutic targets for stroke?
P2860
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P2860
Mammalian ASIC2a and ASIC3 subunits co-assemble into heteromeric proton-gated channels sensitive to Gd3+
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2000 nî lūn-bûn
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2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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Mammalian ASIC2a and ASIC3 sub ...... ted channels sensitive to Gd3+
@ast
Mammalian ASIC2a and ASIC3 sub ...... ted channels sensitive to Gd3+
@en
Mammalian ASIC2a and ASIC3 sub ...... ted channels sensitive to Gd3+
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type
label
Mammalian ASIC2a and ASIC3 sub ...... ted channels sensitive to Gd3+
@ast
Mammalian ASIC2a and ASIC3 sub ...... ted channels sensitive to Gd3+
@en
Mammalian ASIC2a and ASIC3 sub ...... ted channels sensitive to Gd3+
@nl
prefLabel
Mammalian ASIC2a and ASIC3 sub ...... ted channels sensitive to Gd3+
@ast
Mammalian ASIC2a and ASIC3 sub ...... ted channels sensitive to Gd3+
@en
Mammalian ASIC2a and ASIC3 sub ...... ted channels sensitive to Gd3+
@nl
P2093
P2860
P3181
P356
P1476
Mammalian ASIC2a and ASIC3 sub ...... ted channels sensitive to Gd3+
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.M004114200
P407
P577
2000-09-15T00:00:00Z