Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway - Wikidata - wikimedia - TriplyDB

Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway

Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway

http://www.wikidata.org/entity/Q28186388

about

MUTYH the base excision repair gene family member associated with colorectal cancer polyposis The genetic heterogeneity of colorectal cancer predisposition - guidelines for gene discovery Base-excision repair of oxidative DNA damage Clinical characterization and the mutation spectrum in Swedish adenomatous polyposis families.Colorectal carcinomas in MUTYH-associated polyposis display histopathological similarities to microsatellite unstable carcinomas New insights into the molecular pathogenesis of colorectal cancer.The Mutyh base excision repair gene influences the inflammatory response in a mouse model of ulcerative colitis.Absence of MutY homologue mutation in patients with multiple sporadic adenomatous polyps in Korea A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer.Genetic predisposition to colorectal cancer: where we stand and future perspectives Abnormality in Wnt signaling is causatively associated with oxidative stress-induced intestinal tumorigenesis in MUTYH-null mice.MUTYH Associated Polyposis (MAP).The genetic basis of familial adenomatous polyposis and its implications for clinical practice and risk management.Analysis of somatic molecular changes, clinicopathological features, family history, and germline mutations in colorectal cancer families: evidence for efficient diagnosis of HNPCC and for the existence of distinct groups of non-HNPCC families Physical and functional interactions between Escherichia coli MutY glycosylase and mismatch repair protein MutS Mammalian MutY homolog (MYH or MUTYH) protects cells from oxidative DNA damage.Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase Functional characterization of human MutY homolog (hMYH) missense mutation (R231L) that is linked with hMYH-associated polyposis.Genetic architecture of colorectal cancer.Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells.The role of MYH and microsatellite instability in the development of sporadic colorectal cancer.A subgroup of microsatellite stable colorectal cancers has elevated mutation rates and different responses to alkylating and oxidising agents.Colonic polyps in children and adolescents Germline MutY human homologue mutations and colorectal cancer: a multisite case-control study.Pathological features of colorectal carcinomas in MYH-associated polyposis.Distinct functional consequences of MUTYH variants associated with colorectal cancer: Damaged DNA affinity, glycosylase activity and interaction with PCNA and Hus1.Inherited colorectal cancer syndromes.Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer Architecture of inherited susceptibility to colorectal cancer: a voyage of discovery.Impaired suppressive activities of human MUTYH variant proteins against oxidative mutagenesis.Duodenal carcinoma in MUTYH-associated polyposis.MUTYH-associated polyposis (MAP), the syndrome implicating base excision repair in inherited predisposition to colorectal tumors.Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH/MUTYH mutations.Hereditary Colorectal Tumors: A Literature Review on MUTYH-Associated Polyposis.Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase.The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Inherited Polyposis Syndromes.

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P2860

Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway

http://www.wikidata.org/entity/Q28186388

description

2003 nî lūn-bûn

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2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2003 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2003年の論文

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Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway

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Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway

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Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway

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Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway

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Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway

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Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway

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Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway

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Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway

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Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway

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Cancer Research

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Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway

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Amir Sadat

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Angela Jones

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Carole Cummings

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Ella Barclay

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