about
Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancerFunRich: An open access standalone functional enrichment and interaction network analysis toolCarcinogenesis in MYH-associated polyposis follows a distinct genetic pathwayMultiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYHSMAD2, SMAD3 and SMAD4 mutations in colorectal cancerEvaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancerThe TERT variant rs2736100 is associated with colorectal cancer riskGermline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer.A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping dataFunctional screening identifies miRNAs influencing apoptosis and proliferation in colorectal cancer.Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer ProgressionGenetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice.Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal CancerThe adenomatous polyposis coli (APC) tumour suppressor--genetics, function and disease.The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent mannerPHLDA1 expression marks the putative epithelial stem cells and contributes to intestinal tumorigenesis.Mutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted therapy.Impact of BRAF mutation and microsatellite instability on the pattern of metastatic spread and prognosis in metastatic colorectal cancerTolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution.Widespread FRA1-dependent control of mesenchymal transdifferentiation programs in colorectal cancer cells.A mutant BRAF V600E-specific immunohistochemical assay: correlation with molecular mutation status and clinical outcome in colorectal cancer.Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation.Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancerColorectal cancer atlas: An integrative resource for genomic and proteomic annotations from colorectal cancer cell lines and tissues.Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion.Impact of regular aspirin use on overall and cancer-specific survival in patients with colorectal cancer harboring a PIK3CA mutationDifferential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cellsUse of multivariate analysis to suggest a new molecular classification of colorectal cancer.Ectopic expression of P-cadherin correlates with promoter hypomethylation early in colorectal carcinogenesis and enhanced intestinal crypt fission in vivo.DNA copy-number alterations underlie gene expression differences between microsatellite stable and unstable colorectal cancers.Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis.Immunomodulation by MYB is associated with tumor relapse in patients with early stage colorectal cancer.Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer.Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice.Cells with pathogenic biallelic mutations in the human MUTYH gene are defective in DNA damage binding and repair.Colorectal Cancer Cell Line Proteomes are Representative of Primary Tumors and Predict Drug Sensitivity.Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells.Defective Myb Function Ablates Cyclin E1 Expression and Perturbs Intestinal Carcinogenesis.
P50
Q21144952-8E96216E-6CF2-40D2-B136-1B971BC885A6Q24570140-BBC0059C-F099-45D0-BB41-D8440AF7AE6FQ28186388-98C8A056-23CD-4DC2-BF3E-65E8615DCA0DQ28212369-AB2FF337-C14C-406E-B872-ED18F63C3EC0Q28278952-486831C2-2BC2-43E0-BA94-6BD06044595BQ28299100-2C4B1938-BB6F-48B2-B7EA-78795F1EF3B0Q30525527-008F34C6-8839-49FD-86F5-B2B4A35572B7Q30579114-46F07A18-D7FE-4E5C-8227-64489E2F480EQ33630773-8F4D38EC-229D-40A0-B8D2-03123D394B79Q33698545-431C97A1-0927-42EF-B424-5DE0D144206AQ33706508-CDBAB481-5A02-4AA3-8813-90F4CDFB4A40Q33821187-1CB2353F-EC0C-490E-8506-A057EDE35DD9Q33863400-7CFB8492-C637-4979-B692-EF4CAE308535Q34062558-57B675DF-2B86-4233-8430-A0C7E4960042Q34094916-0D04E840-5690-4850-B267-8CBBFBF5ED7AQ34139192-B3056778-BBB8-4513-A0B7-56A225C32226Q34184024-D36E70DA-3DBD-4E30-AE66-26AA39D1EE9AQ34619293-26A9AE54-0F19-4B99-8CAE-D9DE7BB64028Q34628085-18EDD35F-8E34-45E1-ACA3-B44B553B3FD6Q34946877-06005BC1-B4CD-4B52-987D-1EA622491EB7Q35128358-04D702E8-D2B5-457A-9E37-67588E6BB4C7Q35187723-ECACA963-F93E-4948-AF0F-FC0FCEC553F7Q35688605-760FE679-F60D-4CC3-B99B-7BEF45CA0E65Q35760908-6BE4C670-9B6A-41FD-B3B7-EFFA75166840Q36081402-40CD1D22-3FE4-46AE-B859-25CAE78A3EBAQ36434622-3BF63F20-DD8A-4ADF-979D-65F5D832FAE6Q36531671-2E20DE79-DE91-4FB4-AB95-0D80EE6C7E30Q36551145-D8AF6F39-FB09-4BBF-AB5A-D3BF210CD18EQ36652783-811BB62F-AEF7-4CA1-B3D2-B2277E4220E9Q36656389-47C307E5-EA45-4458-B216-B89FB52A1C80Q36922505-742339CC-D815-4196-8208-A224B83AFC68Q37020817-7F7A8540-D6D1-4D27-B065-345C796494B5Q37209240-3C2E555F-A0B3-468B-8064-C332B08AFF05Q37222191-49911C4B-969A-4780-B3FF-6E2D8A4B0A18Q37392742-186B7258-F4BA-4DC3-8537-E55E55117DD1Q38287490-92CCF39A-DA03-40D3-99E8-3D5407F8D01AQ38324266-3DE2CB5E-5057-4F9D-B2E5-3440D312CAFBQ38699958-E12958B9-09BA-4537-A6C0-0882C078070AQ38785795-6B822BF4-2E8A-47C5-889A-5C7998BDDF66Q38879944-BE9FD0E5-0BAC-417F-8A6D-B83E6FF78481
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Oliver Sieber
@ast
Oliver Sieber
@en
Oliver Sieber
@es
Oliver Sieber
@sl
type
label
Oliver Sieber
@ast
Oliver Sieber
@en
Oliver Sieber
@es
Oliver Sieber
@sl
prefLabel
Oliver Sieber
@ast
Oliver Sieber
@en
Oliver Sieber
@es
Oliver Sieber
@sl
P1053
M-9473-2015
P106
P1153
7003368616
P21
P31
P3829
P496
0000-0001-9480-0786