ICOS co-stimulatory receptor is essential for T-cell activation and function - Wikidata - wikimedia - TriplyDB

ICOS co-stimulatory receptor is essential for T-cell activation and function

ICOS co-stimulatory receptor is essential for T-cell activation and function

http://www.wikidata.org/entity/Q28187985

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B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+ T cells Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity No evidence for dualism in function and receptors: PD-L2/B7-DC is an inhibitory regulator of human T cell activation Follicular helper T cells: lineage and location The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells Ligand binding sites of inducible costimulator and high avidity mutants with improved function Current status of immunotherapy Autoimmune therapies targeting costimulation and emerging trends in multivalent therapeutics The role of costimulatory receptors of the tumour necrosis factor receptor family in atherosclerosis Immunoregulatory molecules are master regulators of inflammation during the immune response Tregs Modulate Lymphocyte Proliferation, Activation, and Resident-Memory T-Cell Accumulation within the Brain during MCMV Infection ICOS Co-Stimulation: Friend or Foe?The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling In situ expression and significance of B7 costimulatory molecules within tissues of human gastric carcinoma Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling Expression of the costimulatory molecule B7-H2 (inducible costimulator ligand) by human airway epithelial cells Genetics of type 1 diabetes mellitus Co-stimulatory pathways in lymphocyte regulation: the immunoglobulin superfamily VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity Generation and characterization of B7-H4/B7S1/B7x-deficient mice BTNL2, a butyrophilin-like molecule that functions to inhibit T cell activation The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS)Cloning and characterization of porcine 4Ig-B7-H3: a potent inhibitor of porcine T-cell activation A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 Modulation of NKT cell development by B7-CD28 interaction: an expanding horizon for costimulation.Separable effector T cell populations specialized for B cell help or tissue inflammation.T cell immune abnormalities in immune thrombocytopenia.Inducible costimulator expression regulates the magnitude of Th2-mediated airway inflammation by regulating the number of Th2 cells Correlation of clinical and immunological data in a metastatic melanoma patient with heterogeneous tumor responses to ipilimumab therapy Regulation of T cell response by blocking the ICOS signal with the B7RP-1-specific small antibody fragment isolated from human antibody phage library.ICOS promotes IL-17 synthesis in colonic intraepithelial lymphocytes in IL-10-/- mice.Production of IgG antibodies to pneumococcal polysaccharides is associated with expansion of ICOS+ circulating memory T follicular-helper cells which is impaired by HIV infection.Innate and adaptive immunity in atherosclerosis.The inducible T-cell co-stimulator molecule is expressed on subsets of T cells and is a new marker of lymphomas of T follicular helper cell-derivation.ICOS/ICOSL interaction is required for CD4+ invariant NKT cell function and homeostatic survival.B7h is required for T cell activation, differentiation, and effector function.

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ICOS co-stimulatory receptor is essential for T-cell activation and function

http://www.wikidata.org/entity/Q28187985

description

2001 nî lūn-bûn

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2001 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2001 թվականի հունվարին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

@zh-hant

2001年論文

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2001年論文

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2001年論文

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2001年论文

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name

ICOS co-stimulatory receptor is essential for T-cell activation and function

@ast

ICOS co-stimulatory receptor is essential for T-cell activation and function

@en

ICOS co-stimulatory receptor is essential for T-cell activation and function

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type

label

ICOS co-stimulatory receptor is essential for T-cell activation and function

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ICOS co-stimulatory receptor is essential for T-cell activation and function

@en

ICOS co-stimulatory receptor is essential for T-cell activation and function

@nl

prefLabel

ICOS co-stimulatory receptor is essential for T-cell activation and function

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ICOS co-stimulatory receptor is essential for T-cell activation and function

@en

ICOS co-stimulatory receptor is essential for T-cell activation and function

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ICOS co-stimulatory receptor is essential for T-cell activation and function

@en

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A E Juedes

http://www.w3.org/2001/XMLSchema#string

C Dong

http://www.w3.org/2001/XMLSchema#string

J P Allison

http://www.w3.org/2001/XMLSchema#string

N H Ruddle

http://www.w3.org/2001/XMLSchema#string

R A Flavell

http://www.w3.org/2001/XMLSchema#string

S Shresta

http://www.w3.org/2001/XMLSchema#string

U A Temann

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P2860

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

CD28/B7 system of T cell costimulation

T-cell co-stimulation through B7RP-1 and ICOS

JNK is required for effector T-cell function but not for T-cell activation

Co-stimulation of murine CD4 T cell growth: cooperation between B7 and heat-stable antigen

B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha.

Costimulatory regulation of T cell function.

CTLA-4 and T cell activation.

Studies in B7-deficient mice reveal a critical role for B7 costimulation in both induction and effector phases of experimental autoimmune encephalomyelitis.

A critical role for lymphotoxin in experimental allergic encephalomyelitis.

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2117339

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10.1038/35051100

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6816

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409

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11994434

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1029587160

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11343121

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