WNT pathway and mammary carcinogenesis: loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type - Wikidata - wikimedia - TriplyDB

WNT pathway and mammary carcinogenesis: loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type

WNT pathway and mammary carcinogenesis: loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type

http://www.wikidata.org/entity/Q28191099

about

Carcinogenesis and translational controls: TACC1 is down-regulated in human cancers and associates with mRNA regulators Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism Methylation-associated silencing of SFRP1 with an 8p11-12 amplification inhibits canonical and non-canonical WNT pathways in breast cancers Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer The Wnt antagonist sFRP1 is downregulated in premalignant large bowel adenomas The Wnt-dependent signaling pathways as target in oncology drug discovery Wnt signalling via the epidermal growth factor receptor: a role in breast cancer?Deletions of chromosome 8p and loss of sFRP1 expression are progression markers of papillary bladder cancer Differential impact of tumor suppressor pathways on DNA damage response and therapy-induced transformation in a mouse primary cell model Small molecule antagonists of the Wnt/β-catenin signaling pathway target breast tumor-initiating cells in a Her2/Neu mouse model of breast cancer Transcriptional regulation of the promoter of the rat frizzled related protein gene by CREB The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis The Discovery of Novel Biomarkers Improves Breast Cancer Intrinsic Subtype Prediction and Reconciles the Labels in the METABRIC Data Set.Signalling pathways implicated in early mammary gland morphogenesis and breast cancer.Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma Gene expression profiling of the tumor microenvironment during breast cancer progression.MMTV-Wnt1 and -DeltaN89beta-catenin induce canonical signaling in distinct progenitors and differentially activate Hedgehog signaling within mammary tumors Molecular Signaling of Progesterone, Growth Hormone, Wnt, and HER in Mammary Glands of Dogs, Rodents, and Humans: New Treatment Target Identification.Wnt signaling activation and mammary gland hyperplasia in MMTV-LRP6 transgenic mice: implication for breast cancer tumorigenesis.Wnt1 expression induces short-range and long-range cell recruitments that modify mammary tumor development and are not induced by a cell-autonomous beta-catenin effector Mammary development and breast cancer: the role of stem cells Effects of EpCAM overexpression on human breast cancer cell lines Wnt signaling can substitute for estrogen to induce division of ERalpha-positive cells in a mouse mammary tumor model.Mesd is a universal inhibitor of Wnt coreceptors LRP5 and LRP6 and blocks Wnt/beta-catenin signaling in cancer cells.Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration.Hypermethylation and aberrant expression of Wnt antagonist secreted frizzled-related protein 1 in gastric cancer Wnt1 and Wnt5a induce cyclin D1 expression through ErbB1 transactivation in HC11 mammary epithelial cells.Differential expression of centrosome regulators in Her2+ breast cancer cells versus non-tumorigenic MCF10A cells.MENA is a transcriptional target of the Wnt/beta-catenin pathway.Wnt and mammary stem cells: hormones cannot fly wingless.The transcripts of SFRP1,CEP63 and EIF4G2 genes are frequently downregulated in transitional cell carcinomas of the bladder.Targeting breast stem cells with the cancer preventive compounds curcumin and piperine.Key signaling nodes in mammary gland development and cancer: β-catenin.Association of single nucleotide polymorphisms in Wnt signaling pathway genes with breast cancer in Saudi patients.Expression of SFRP Family Proteins in Human Keratoconus Corneas.Secreted Frizzled-related proteins: searching for relationships and patterns.Breast cancer, stem cells and prospects for therapy.BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells.Use of integrative epigenetic and cytogenetic analyses to identify novel tumor-suppressor genes in malignant melanoma The Wnt antagonist sFRP1 as a favorable prognosticator in human biliary tract carcinoma.

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WNT pathway and mammary carcinogenesis: loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type

http://www.wikidata.org/entity/Q28191099

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2001 nî lūn-bûn

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2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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P2860

Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling

Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signaling

Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells

Up-regulation of human secreted frizzled homolog in apoptosis and its down-regulation in breast tumors

Identification of c-MYC as a target of the APC pathway

Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action

SARPs: a family of secreted apoptosis-related proteins

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors

Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4

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