MMTV-Wnt1 and -DeltaN89beta-catenin induce canonical signaling in distinct progenitors and differentially activate Hedgehog signaling within mammary tumors - Wikidata - wikimedia - TriplyDB

MMTV-Wnt1 and -DeltaN89beta-catenin induce canonical signaling in distinct progenitors and differentially activate Hedgehog signaling within mammary tumors

MMTV-Wnt1 and -DeltaN89beta-catenin induce canonical signaling in distinct progenitors and differentially activate Hedgehog signaling within mammary tumors

http://www.wikidata.org/entity/Q33410269

about

A systematic screen for micro-RNAs regulating the canonical Wnt pathway The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development Both canonical and non-canonical Wnt signaling independently promote stem cell growth in mammospheres Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture Pea3 transcription factors and wnt1-induced mouse mammary neoplasia Wnt5a Signaling in Normal and Cancer Stem Cells Beta-catenin signaling negatively regulates intermediate progenitor population numbers in the developing cortex.Molecular mechanisms guiding embryonic mammary gland development.The cytoplasmic domain of MUC1 induces hyperplasia in the mammary gland and correlates with nuclear accumulation of β-catenin.Differentiation generates paracrine cell pairs that maintain basaloid mouse mammary tumors: proof of concept.Epithelial stem cells: an epigenetic and Wnt-centric perspective.Activation status of Wnt/ß-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouse Myc is required for β-catenin-mediated mammary stem cell amplification and tumorigenesis.Expression of dickkopf-1 and beta-catenin related to the prognosis of breast cancer patients with triple negative phenotype.Wnt and mammary stem cells: hormones cannot fly wingless.WNT10A plays an oncogenic role in renal cell carcinoma by activating WNT/β-catenin pathway.Wnt5a suppresses tumor formation and redirects tumor phenotype in MMTV-Wnt1 tumors.Key signaling nodes in mammary gland development and cancer: β-catenin.Tumor-initiating cells are not enriched in cisplatin-surviving BRCA1;p53-deficient mammary tumor cells in vivo.Stromal mediation of radiation carcinogenesis.Wnt5a as an effector of TGFβ in mammary development and cancer Conditional deletion of β-catenin in mammary epithelial cells of Ron receptor, Mst1r, overexpressing mice alters mammary tumorigenesis.Overexpression of Id1 in transgenic mice promotes mammary basal stem cell activity and breast tumorigenesis Wnt signaling in mammary glands: plastic cell fates and combinatorial signaling.WNT10B/β-catenin signalling induces HMGA2 and proliferation in metastatic triple-negative breast cancer.RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer.IGF1R inhibition in mammary epithelia promotes canonical Wnt signaling and Wnt1-driven tumors Baicalein suppresses metastasis of breast cancer cells by inhibiting EMT via downregulation of SATB1 and Wnt/β-catenin pathway.Wnt/β-catenin Signaling in Normal and Cancer Stem Cells.Skeletal metastasis: treatments, mouse models, and the Wnt signaling.Chromatin effector Pygo2 regulates mammary tumor initiation and heterogeneity in MMTV-Wnt1 mice.Normal mammary development and function in mice with Ift88 deleted in MMTV- and K14-Cre expressing cells Tracing the origins of metastasis.The Wnt/β-catenin signaling pathway: a potential therapeutic target in the treatment of triple negative breast cancer.p53 deficiency induces cancer stem cell pool expansion in a mouse model of triple-negative breast tumors.Is there more to Wnt signalling in breast cancer than stabilisation of beta-catenin?Links between transforming growth factor-beta and canonical Wnt signaling yield new insights into breast cancer susceptibility, suppression and tumor heterogeneity.A mouse transgenic approach to induce β-catenin signaling in a temporally controlled manner.Tumour cell invasiveness and response to chemotherapeutics in adipocyte invested 3D engineered anisotropic collagen scaffolds

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P2860

MMTV-Wnt1 and -DeltaN89beta-catenin induce canonical signaling in distinct progenitors and differentially activate Hedgehog signaling within mammary tumors

http://www.wikidata.org/entity/Q33410269

description

2009 nî lūn-bûn

@nan

2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի փետրվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

MMTV-Wnt1 and -DeltaN89beta-ca ...... ignaling within mammary tumors

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MMTV-Wnt1 and -DeltaN89beta-ca ...... ignaling within mammary tumors

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type

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MMTV-Wnt1 and -DeltaN89beta-ca ...... ignaling within mammary tumors

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MMTV-Wnt1 and -DeltaN89beta-ca ...... ignaling within mammary tumors

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MMTV-Wnt1 and -DeltaN89beta-ca ...... ignaling within mammary tumors

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MMTV-Wnt1 and -DeltaN89beta-ca ...... ignaling within mammary tumors

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MMTV-Wnt1 and -DeltaN89beta-ca ...... ignaling within mammary tumors

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Alicia Pinderhughes

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Angela Incassati

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Brigitte Teissedre

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Minoti Hiremath

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Pamela Cowin

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Sarah J Hatsell

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P2860

Prospective identification of tumorigenic breast cancer cells

Functional and molecular characterisation of mammary side population cells

Identification of stem cells in small intestine and colon by marker gene Lgr5

beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin

WNT pathway and mammary carcinogenesis: loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type

Wnt5a is required for proper mammary gland development and TGF-beta-mediated inhibition of ductal growth

Gli3-mediated repression of Hedgehog targets is required for normal mammary development

The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis

A sensitized mutagenesis screen identifies Gli3 as a modifier of Sox10 neurocristopathy

Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1

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