CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin
about
Hemoglobin and its scavenger protein haptoglobin associate with apoA-1-containing particles and influence the inflammatory properties and function of high density lipoproteinSequestration of extracellular hemoglobin within a haptoglobin complex decreases its hypertensive and oxidative effects in dogs and guinea pigsPotential Use of Biological Proteins for Liver Failure TherapyNatural history of the bruise: formation, elimination, and biological effects of oxidized hemoglobinThe haptoglobin-CD163-heme oxygenase-1 pathway for hemoglobin scavengingHaptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug developmentThe genome response to artificial selection: a case study in dairy cattle.Application of selection mapping to identify genomic regions associated with dairy production in sheep.Heme degradation and vascular injury.Antigenic and Biological Characterization of ORF2-6 Variants at Early Times Following PRRSV InfectionThe tissue microlocalisation and cellular expression of CD163, VEGF, HLA-DR, iNOS, and MRP 8/14 is correlated to clinical outcome in NSCLCHeme oxygenase-1 dysregulation in the brain: implications for HIV-associated neurocognitive disorders.Down selection of polymerized bovine hemoglobins for use as oxygen releasing therapeutics in a guinea pig modelHeme oxygenase-1 deficiency accompanies neuropathogenesis of HIV-associated neurocognitive disordersModeling hemoglobin and hemoglobin:haptoglobin complex clearance in a non-rodent species-pharmacokinetic and therapeutic implications.Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function.Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cellsAn alternative view of the proposed alternative activities of hemopexin.BANK1 and BLK act through phospholipase C gamma 2 in B-cell signalingHeme carrier protein (HCP-1) spatially interacts with the CD163 hemoglobin uptake pathway and is a target of inflammatory macrophage activation.Hemophagocytic macrophages constitute a major compartment of heme oxygenase expression in sepsisIntegrated genomic approaches to identification of candidate genes underlying metabolic and cardiovascular phenotypes in the spontaneously hypertensive rat.Hemoglobin directs macrophage differentiation and prevents foam cell formation in human atherosclerotic plaquesHemoglobin-driven pathophysiology is an in vivo consequence of the red blood cell storage lesion that can be attenuated in guinea pigs by haptoglobin therapy.Critical illness induces alternative activation of M2 macrophages in adipose tissueHuman endometriosis is associated with plasma cells and overexpression of B lymphocyte stimulatorTargeting the hemoglobin scavenger receptor CD163 in macrophages highly increases the anti-inflammatory potency of dexamethasone.Genetic Modifiers of White Blood Cell Count, Albuminuria and Glomerular Filtration Rate in Children with Sickle Cell Anemia.The Mechanism of Proinflammatory HDL Generation in Sickle Cell Disease Is Linked to Cell-Free Hemoglobin via Haptoglobin.Solution structure of poly(ethylene) glycol-conjugated hemoglobin revealed by small-angle X-ray scattering: implications for a new oxygen therapeuticIntraoperative High-Dose Dexamethasone and Severe AKI after Cardiac SurgeryErythrocyte storage increases rates of NO and nitrite scavenging: implications for transfusion-related toxicity.Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteinsHaptoglobin binding stabilizes hemoglobin ferryl iron and the globin radical on tyrosine β145First-generation blood substitutes: what have we learned? Biochemical and physiological perspectives.Cell-free hemoglobin and its scavenger proteins: new disease models leading the way to targeted therapiesChloroquine interference with hemoglobin endocytic trafficking suppresses adaptive heme and iron homeostasis in macrophages: the paradox of an antimalarial agent.Age-Dependent Effects of Haptoglobin Deletion in Neurobehavioral and Anatomical Outcomes Following Traumatic Brain Injury.Coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype.Human Hp1-1 and Hp2-2 phenotype-specific haptoglobin therapeutics are both effective in vitro and in guinea pigs to attenuate hemoglobin toxicity.
P2860
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P2860
CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
CD163 is the macrophage scaven ...... in the absence of haptoglobin
@ast
CD163 is the macrophage scaven ...... in the absence of haptoglobin
@en
CD163 is the macrophage scaven ...... in the absence of haptoglobin
@nl
type
label
CD163 is the macrophage scaven ...... in the absence of haptoglobin
@ast
CD163 is the macrophage scaven ...... in the absence of haptoglobin
@en
CD163 is the macrophage scaven ...... in the absence of haptoglobin
@nl
prefLabel
CD163 is the macrophage scaven ...... in the absence of haptoglobin
@ast
CD163 is the macrophage scaven ...... in the absence of haptoglobin
@en
CD163 is the macrophage scaven ...... in the absence of haptoglobin
@nl
P2093
P3181
P1433
P1476
CD163 is the macrophage scaven ...... in the absence of haptoglobin
@en
P2093
Abdu I Alayash
Andreas Schaffner
Christian A Schaer
Dominik J Schaer
Gabriele Schoedon
Paul W Buehler
Robert A Boykins
P304
P3181
P356
10.1182/BLOOD-2005-03-1014
P407
P577
2006-01-01T00:00:00Z