Fibroblast growth factor (FGF)-23 inhibits renal phosphate reabsorption by activation of the mitogen-activated protein kinase pathway
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Brorin, a novel secreted bone morphogenetic protein antagonist, promotes neurogenesis in mouse neural precursor cellsSecreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agentVitamin D and the kidneyRegulation and function of the FGF23/klotho endocrine pathwaysFibroblast Growth Factor 23: A New Dimension to Diseases of Calcium-Phosphorus MetabolismGenetic basis of irritant susceptibility in health care workersFGF23, PHEX, and MEPE regulation of phosphate homeostasis and skeletal mineralizationHuman fibroblast growth factor-23 mutants suppress Na+-dependent phosphate co-transport activity and 1alpha,25-dihydroxyvitamin D3 productionFibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1alpha-hydroxylase expression in vitroThe parathyroid is a target organ for FGF23 in ratsRegulation of fibroblast growth factor-23 signaling by klothoEffects of cinacalcet and concurrent low-dose vitamin D on FGF23 levels in ESRD.Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation.Nuclear isoforms of fibroblast growth factor 2 are novel inducers of hypophosphatemia via modulation of FGF23 and KLOTHOFibroblast growth factor-23 increases mouse PGE2 production in vivo and in vitro.FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.Phosphatonin washout in Hyp mice proximal tubules: evidence for posttranscriptional regulation.Analysis of the biochemical mechanisms for the endocrine actions of fibroblast growth factor-23Velcalcetide (AMG 416), a novel peptide agonist of the calcium-sensing receptor, reduces serum parathyroid hormone and FGF23 levels in healthy male subjectsElevated FGF23 levels are associated with impaired calcium-mediated suppression of PTH in ESRD.Antibody-mediated activation of FGFR1 induces FGF23 production and hypophosphatemia.Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype.Regulation of phosphate transport by fibroblast growth factor 23 (FGF23): implications for disorders of phosphate metabolism.Fibroblast growth factor-23-mediated inhibition of renal phosphate transport in mice requires sodium-hydrogen exchanger regulatory factor-1 (NHERF-1) and synergizes with parathyroid hormone.Selection of a novel FGF23-binding peptide antagonizing the inhibitory effect of FGF23 on phosphate uptake.Fibroblast growth factor 23 regulates renal 1,25-dihydroxyvitamin D and phosphate metabolism via the MAP kinase signaling pathway in Hyp miceEvidence for a bone-kidney axis regulating phosphate homeostasis.Chronic inhibition of ERK1/2 signaling improves disordered bone and mineral metabolism in hypophosphatemic (Hyp) mice.The wrickkened pathways of FGF23, MEPE and PHEX.Phosphate: known and potential roles during development and regeneration of teeth and supporting structures.NHERF-1 and the regulation of renal phosphate reabsoption: a tale of three hormonesFibroblast growth factor 23 and its receptors."Phosphatonins" and the regulation of phosphorus homeostasis.The consequences of chronic kidney disease on bone metabolism and growth in children.Phosphaturic Mesenchymal Tumor: 2 New Oral Cases and Review of 53 Cases in the Head and Neck.The emerging role of the fibroblast growth factor-23-klotho axis in renal regulation of phosphate homeostasisEndocrine functions of bone in mineral metabolism regulation.Current understanding of klotho.Kidney and phosphate metabolism.FGF23 and syndromes of abnormal renal phosphate handling
P2860
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P2860
Fibroblast growth factor (FGF)-23 inhibits renal phosphate reabsorption by activation of the mitogen-activated protein kinase pathway
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Fibroblast growth factor (FGF) ...... tivated protein kinase pathway
@ast
Fibroblast growth factor (FGF) ...... tivated protein kinase pathway
@en
Fibroblast growth factor (FGF) ...... tivated protein kinase pathway
@nl
type
label
Fibroblast growth factor (FGF) ...... tivated protein kinase pathway
@ast
Fibroblast growth factor (FGF) ...... tivated protein kinase pathway
@en
Fibroblast growth factor (FGF) ...... tivated protein kinase pathway
@nl
prefLabel
Fibroblast growth factor (FGF) ...... tivated protein kinase pathway
@ast
Fibroblast growth factor (FGF) ...... tivated protein kinase pathway
@en
Fibroblast growth factor (FGF) ...... tivated protein kinase pathway
@nl
P2093
P2860
P356
P1476
Fibroblast growth factor (FGF) ...... tivated protein kinase pathway
@en
P2093
Ayumi Miyake
Ken-ichi Inui
Morichika Konishi
Nobuyuki Itoh
Tetsuo Yamashita
P2860
P304
P356
10.1074/JBC.M202527200
P407
P577
2002-08-02T00:00:00Z