Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation.
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Klotho, stem cells, and agingFibroblast growth factor 23Fibrous dysplasia and fibroblast growth factor-23 regulationFamilial tumoral calcinosis: a valuable vehicle for discoveryExploring mechanisms of FGF signalling through the lens of structural biologyKlotho and phosphate are modulators of pathologic uremic cardiac remodeling.Vascular calcification: When should we interfere in chronic kidney disease patients and how?Dysregulation of phosphate metabolism and conditions associated with phosphate toxicityMolecular mechanisms of fibroblast growth factor signaling in physiology and pathologyN-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models1,25-dihydroxyvitamin D(3) regulation of fibroblast growth factor-23 expression in bone cells: evidence for primary and secondary mechanisms modulated by leptin and interleukin-6FGF23 deficiency leads to mixed hearing loss and middle ear malformation in mice.Fibroblast growth factor 23 and Klotho: physiology and pathophysiology of an endocrine network of mineral metabolismFGF23 and vascular calcifications: another piece of the puzzle?Inhibitor of ppGalNAc-T3-mediated O-glycosylation blocks cancer cell invasiveness and lowers FGF23 levels.O-glycosylation modulates proprotein convertase activation of angiopoietin-like protein 3: possible role of polypeptide GalNAc-transferase-2 in regulation of concentrations of plasma lipidsFGF23 is synthesised locally by renal tubules and activates injury-primed fibroblasts.The use of fibroblast growth factor 23 testing in patients with kidney disease.Short hairpin RNA screen indicates that Klotho beta/FGF19 protein overcomes stasis in human colonic epithelial cellsHypophosphatemic rickets: revealing novel control points for phosphate homeostasis.Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule.The changing face of hypophosphatemic disorders in the FGF-23 eraBone biomarkers help grading severity of coronary calcifications in non dialysis chronic kidney disease patients.Klotho deficiency causes vascular calcification in chronic kidney disease.Severe vascular calcification and tumoral calcinosis in a family with hyperphosphatemia: a fibroblast growth factor 23 mutation identified by exome sequencingKlotho inhibits transforming growth factor-beta1 (TGF-beta1) signaling and suppresses renal fibrosis and cancer metastasis in miceRecent advances in renal phosphate handling.Effects of dietary phosphate and calcium intake on fibroblast growth factor-23Iron and obesity status-associated insulin resistance influence circulating fibroblast-growth factor-23 concentrationsArterial klotho expression and FGF23 effects on vascular calcification and function.Implications of Klotho in vascular health and disease.The demonstration of αKlotho deficiency in human chronic kidney disease with a novel synthetic antibodyElevated Klotho promoter methylation is associated with severity of chronic kidney diseaseOsteo-renal regulation of systemic phosphate metabolism.Phosphate toxicity: new insights into an old problemParathyroid-specific deletion of Klotho unravels a novel calcineurin-dependent FGF23 signaling pathway that regulates PTH secretion.Molecular basis of Klotho: from gene to function in agingSelection of a novel FGF23-binding peptide antagonizing the inhibitory effect of FGF23 on phosphate uptake.Klotho and kidney disease.Relation between Red Cell Distribution Width and Fibroblast Growth Factor 23 Cleaving in Patients with Chronic Kidney Disease and Heart Failure
P2860
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P2860
Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Isolated C-terminal tail of FG ...... FGFR-Klotho complex formation.
@ast
Isolated C-terminal tail of FG ...... FGFR-Klotho complex formation.
@en
type
label
Isolated C-terminal tail of FG ...... FGFR-Klotho complex formation.
@ast
Isolated C-terminal tail of FG ...... FGFR-Klotho complex formation.
@en
prefLabel
Isolated C-terminal tail of FG ...... FGFR-Klotho complex formation.
@ast
Isolated C-terminal tail of FG ...... FGFR-Klotho complex formation.
@en
P2093
P2860
P921
P356
P1476
Isolated C-terminal tail of FG ...... FGFR-Klotho complex formation.
@en
P2093
Anna V Eliseenkova
Hiroshi Kurosu
Makoto Kuro-o
Ming Chang Hu
Mingjun Shi
Mohammed S Razzaque
Orson W Moe
Teruyo Nakatani
Yuji Nakada
P2860
P304
P356
10.1073/PNAS.0902006107
P407
P577
2009-12-04T00:00:00Z