The Wiskott-Aldrich syndrome protein (WASP): roles in signaling and cytoskeletal organization
about
Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffoldActin-based motility of intracellular microbial pathogensLoss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice.The Wiskott-Aldrich syndromeThe molecular pathology of primary immunodeficienciesHuman Immunodeficiencies Related to Defective APC/T Cell InteractionStimulation of M3 muscarinic receptors induces phosphorylation of the Cdc42 effector activated Cdc42Hs-associated kinase-1 via a Fyn tyrosine kinase signaling pathwayA mutation in the pleckstrin homology (PH) domain of the FGD1 gene in an Italian family with faciogenital dysplasia (Aarskog-Scott syndrome)The anti-leukemic Bruton's tyrosine kinase inhibitor alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl) propenamide (LFM-A13) prevents fatal thromboembolismRich, a rho GTPase-activating protein domain-containing protein involved in signaling by Cdc42 and Rac1CD28 and CTLA-4 coreceptor expression and signal transductionWiskott-Aldrich syndrome protein and the cytoskeletal dynamics of dendritic cellsHematopoietic adaptors in T-cell signaling: potential applications to transplantationFOXP3+ Tregs require WASP to restrain Th2-mediated food allergyPlatelet actin nodules are podosome-like structures dependent on Wiskott-Aldrich syndrome protein and ARP2/3 complex.WASP deficiency leads to global defects of directed leukocyte migration in vitro and in vivo.Wiskott-Aldrich syndrome: a comprehensive review.Combined de-novo mutation and non-random X-chromosome inactivation causing Wiskott-Aldrich syndrome in a female with thrombocytopenia.Wiskott-Aldrich syndrome/X-linked thrombocytopenia in China: Clinical characteristic and genotype-phenotype correlation.CR16 forms a complex with N-WASP in human testes.WASp verprolin homology, cofilin homology, and acidic region domain-mediated actin polymerization is required for T cell development.An enigmatic tail of CD28 signaling.Molecular links between endocytosis and the actin cytoskeleton.N-WASP has the ability to compensate for the loss of WASP in macrophage podosome formation and chemotaxisT-cell receptor signaling to integrins.Understanding Rho/Rac biology in T-cells using animal models.Genetic analysis of integrin activation in T lymphocytes.Second-site mutation in the Wiskott-Aldrich syndrome (WAS) protein gene causes somatic mosaicism in two WAS siblings.Itk: the rheostat of the T cell response.WASP-interacting protein is important for actin filament elongation and prompt pseudopod formation in response to a dynamic chemoattractant gradient.Regulation of cytoskeletal dynamics at the immune synapse: new stars join the actin troupeItk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP.Cutaneous signs of neonatal and infantile immunodeficiency.Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers.Implications of polyadenylation in health and disease.RhoA is required for monocyte tail retraction during transendothelial migration.Osmotic stress and the cytoskeleton: the R(h)ole of Rho GTPases.1-42 β-amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death.Mechanism and rate constants of the Cdc42 GTPase binding with intrinsically disordered effectors.Wiskott-Aldrich syndrome proteins in the nucleus: aWASH with possibilities
P2860
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P2860
The Wiskott-Aldrich syndrome protein (WASP): roles in signaling and cytoskeletal organization
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The Wiskott-Aldrich syndrome p ...... and cytoskeletal organization
@ast
The Wiskott-Aldrich syndrome p ...... and cytoskeletal organization
@en
The Wiskott-Aldrich syndrome p ...... and cytoskeletal organization
@nl
type
label
The Wiskott-Aldrich syndrome p ...... and cytoskeletal organization
@ast
The Wiskott-Aldrich syndrome p ...... and cytoskeletal organization
@en
The Wiskott-Aldrich syndrome p ...... and cytoskeletal organization
@nl
altLabel
THE WISKOTT-ALDRICH SYNDROME P ...... and Cytoskeletal Organization
@en
prefLabel
The Wiskott-Aldrich syndrome p ...... and cytoskeletal organization
@ast
The Wiskott-Aldrich syndrome p ...... and cytoskeletal organization
@en
The Wiskott-Aldrich syndrome p ...... and cytoskeletal organization
@nl
P2093
P1476
THE WISKOTT-ALDRICH SYNDROME P ...... and Cytoskeletal Organization
@en
The Wiskott-Aldrich syndrome p ...... and cytoskeletal organization
@en
P2093
Fred S. Rosen
S B Snapper
Scott B. Snapper
P356
10.1146/ANNUREV.IMMUNOL.17.1.905
P407
P577
1999-04-01T00:00:00Z