Structure-function relationships and site of action of apamin, a neurotoxic polypeptide of bee venom with an action on the central nervous system
about
sameAs
Cobatoxin 1 from Centruroides noxius scorpion venom: chemical synthesis, three-dimensional structure in solution, pharmacology and docking on K+ channelsA human intermediate conductance calcium-activated potassium channelSolution structure of hpTX2, a toxin from Heteropoda venatoria spider that blocks Kv4.2 potassium channelA novel small conductance Ca2+-activated K+ channel blocker from Oxyuranus scutellatus taipan venom. Re-evaluation of taicatoxin as a selective Ca2+ channel probeCharacterization of a new peptide from Tityus serrulatus scorpion venom which is a ligand of the apamin-binding siteSolution conformation of leiurotoxin I (scyllatoxin) by 1H nuclear magnetic resonance. Resonance assignment and secondary structure.Allosteric block of KCa2 channels by apamin.Concept of internal structural controls for evaluation of inactive synthetic peptide analogs: synthesis of [Orn13,14]apamin and its guanidination to an apamin derivative with full neurotoxic activity.Apamin as a selective blocker of the calcium-dependent potassium channel in neuroblastoma cells: voltage-clamp and biochemical characterization of the toxin receptorBinding of sea anemone toxin to receptor sites associated with gating system of sodium channel in synaptic nerve endings in vitro.The presence in pig brain of an endogenous equivalent of apamin, the bee venom peptide that specifically blocks Ca2+-dependent K+ channels.Blood-brain barrier shuttle peptides: an emerging paradigm for brain delivery.Characterization and regulation of the expression of scyllatoxin (Leiurotoxin I) receptors in the human neuroblastoma cell line NB-OK 1.A four-disulphide-bridged toxin, with high affinity towards voltage-gated K+ channels, isolated from Heterometrus spinnifer (Scorpionidae) venom.Towards therapeutic applications of arthropod venom k(+)-channel blockers in CNS neurologic diseases involving memory acquisition and storage.Determinants of apamin and d-tubocurarine block in SK potassium channels.Characterization of a new leiurotoxin I-like scorpion toxin. PO5 from Androctonus mauretanicus mauretanicus.From venoms to BBB shuttles: Synthesis and blood-brain barrier transport assessment of apamin and a nontoxic analog.
P2860
Q24530587-D1AFF9CF-BF00-46DC-BA75-5F4A2FFBA179Q24654684-170F9252-5F71-4F64-8E04-3446A3A3F7CDQ24672436-BE9EE8CE-8981-44CE-A3C2-10A55AD047D3Q28245185-8A2C91B8-F723-47AA-A6B3-B103DBBDC9C4Q28284844-0D963EDF-CD27-4E93-85C1-CBD79AF4D0F8Q33887563-75212E56-C4C5-4DF7-B994-E2E1408C1D30Q34094456-B414158B-BBB0-49B2-B002-1EBD4D4BF9D7Q35034839-79CA96C3-4200-4AD5-99BE-D735294D8B65Q36283529-560C4CB2-DA54-4458-8DD1-244C5FDC75B8Q36361171-55BF8B25-52EA-4C71-8961-3A77C606C2A4Q37577825-45703B3C-B3F7-4950-9CC2-0995A4F0E015Q38836486-4188A0B3-1FFC-4CF2-AD04-26FD315595A1Q41674116-A7DC58B7-F6AD-4B17-BA48-1285C210F817Q42159545-FBFBC53F-010D-4289-BEA6-31027AD76835Q42175839-40ECEDAE-74F1-4536-A27B-0BB18C06ED7FQ42547803-76CE19E0-221E-4FB5-9D1A-5FD9E5302723Q48303838-ADF95C16-9715-46EA-825D-A04E1C8AAB7AQ48842644-D2D96B33-2855-4848-92AA-DCBC2BD5569C
P2860
Structure-function relationships and site of action of apamin, a neurotoxic polypeptide of bee venom with an action on the central nervous system
description
1975 nî lūn-bûn
@nan
1975 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1975 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1975年の論文
@ja
1975年論文
@yue
1975年論文
@zh-hant
1975年論文
@zh-hk
1975年論文
@zh-mo
1975年論文
@zh-tw
1975年论文
@wuu
name
Structure-function relationshi ...... on the central nervous system
@ast
Structure-function relationshi ...... on the central nervous system
@en
Structure-function relationshi ...... on the central nervous system
@nl
type
label
Structure-function relationshi ...... on the central nervous system
@ast
Structure-function relationshi ...... on the central nervous system
@en
Structure-function relationshi ...... on the central nervous system
@nl
prefLabel
Structure-function relationshi ...... on the central nervous system
@ast
Structure-function relationshi ...... on the central nervous system
@en
Structure-function relationshi ...... on the central nervous system
@nl
P356
P1433
P1476
Structure-function relationshi ...... on the central nervous system
@en
P2093
H Schweitz
J P Vincent
P304
P356
10.1021/BI00682A035
P407
P577
1975-06-03T00:00:00Z