Association of a new-type prostaglandin D2 receptor CRTH2 with circulating T helper 2 cells in patients with atopic dermatitis
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Aldo-keto reductase 1C3 is expressed in differentiated human epidermis, affects keratinocyte differentiation, and is upregulated in atopic dermatitisIdentification of determinants of ligand binding affinity and selectivity in the prostaglandin D2 receptor CRTH2Sequence variants of the gene encoding chemoattractant receptor expressed on Th2 cells (CRTH2) are associated with asthma and differentially influence mRNA stabilityPossible novel receptor for PGD2 on human bronchial epithelial cellsProstanoid receptor antagonists: development strategies and therapeutic applicationsThe prostaglandin D₂ receptor CRTH2 is important for allergic skin inflammation after epicutaneous antigen challenge.Prostaglandins and inflammation.Chemoattractant receptor homologous to the T helper 2 cell (CRTH2) is not expressed in human amniocytes and myocytes.Genetic impact of functional single nucleotide polymorphisms in the 3'-UTR region of the chemoattractant receptor expressed on Th2 cells (CRTH2) gene on asthma and atopy in a Japanese population.TSLP promotes induction of Th2 differentiation but is not necessary during established allergen-induced pulmonary disease.Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.Th2 Cytokines and Atopic Dermatitis.GATA3 up-regulation associated with surface expression of CD294/CRTH2: a unique feature of human Th cells.CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation.Antagonism of CRTH2 ameliorates chronic epicutaneous sensitization-induced inflammation by multiple mechanismsA small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.Efficacy and safety of setipiprant in seasonal allergic rhinitis: results from Phase 2 and Phase 3 randomized, double-blind, placebo- and active-referenced studies.Molecular biology of atopic dermatitis.The immunology of atopic dermatitis and its reversibility with broad-spectrum and targeted therapies.Anti-inflammatory therapies in atopic dermatitis.The interplay between genetic and environmental factors in the pathogenesis of atopic dermatitis.Optimization of the Central Core of Indolinone-Acetic Acid-Based CRTH2 (DP2) Receptor Antagonists.Association of CRTH2 gene polymorphisms with the required dose of antihistamines in patients with chronic urticaria.The etiopathogenesis of atopic dermatitis: barrier disruption, immunological derangement, and pruritus.Elevated levels of circulating CD4(+) CRTh2(+) T cells characterize severe asthma.Effect of oral eicosapentaenoic acid on epidermal Langerhans cell numbers and PGD2 production in UVR-exposed human skin: a randomised controlled study.A paracrine role for chemoattractant receptor-homologous molecule expressed on T helper type 2 cells (CRTH2) in mediating chemotactic activation of CRTH2+ CD4+ T helper type 2 lymphocytes.Exposure of Intestinal Epithelial Cells to Short- and Long-Chain Fructo-Oligosaccharides and CpG Oligodeoxynucleotides Enhances Peanut-Specific T Helper 1 Polarization.
P2860
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P2860
Association of a new-type prostaglandin D2 receptor CRTH2 with circulating T helper 2 cells in patients with atopic dermatitis
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Association of a new-type pros ...... atients with atopic dermatitis
@ast
Association of a new-type pros ...... atients with atopic dermatitis
@en
Association of a new-type pros ...... atients with atopic dermatitis
@nl
type
label
Association of a new-type pros ...... atients with atopic dermatitis
@ast
Association of a new-type pros ...... atients with atopic dermatitis
@en
Association of a new-type pros ...... atients with atopic dermatitis
@nl
prefLabel
Association of a new-type pros ...... atients with atopic dermatitis
@ast
Association of a new-type pros ...... atients with atopic dermatitis
@en
Association of a new-type pros ...... atients with atopic dermatitis
@nl
P2093
P1476
Association of a new-type pros ...... atients with atopic dermatitis
@en
P2093
Kazuo Takahashi
Kinya Nagata
Masahiro Iwasaki
Norihisa Ishii
Shoichi Takano
Zenro Ikezawa
P304
P356
10.1046/J.1523-1747.2002.01862.X
P407
P577
2002-09-01T00:00:00Z
P5875
P6179
1026573756