Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins
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A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transportSlp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapseAlternative splicing isoforms of synaptotagmin VII in the mouse, rat and humanThe Rab27a-binding protein, JFC1, regulates androgen-dependent secretion of prostate-specific antigen and prostatic-specific acid phosphataseMutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden miceRegulation of vesicular trafficking and leukocyte function by Rab27 GTPases and their effectorsGenome-wide association identifies multiple genomic regions associated with susceptibility to and control of ovine lentivirus.Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transportDistinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cellsThe Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domainThe N-terminal cysteine cluster is essential for membrane targeting of B/K proteinThe leaden gene product is required with Rab27a to recruit myosin Va to melanosomes in melanocytesRabphilin and Noc2 are recruited to dense-core vesicles through specific interaction with Rab27A in PC12 cellsThe C2B domain of rabphilin directly interacts with SNAP-25 and regulates the docking step of dense core vesicle exocytosis in PC12 cellsSlac2-c (synaptotagmin-like protein homologue lacking C2 domains-c), a novel linker protein that interacts with Rab27, myosin Va/VIIa, and actinComparative genomics reveals insights into avian genome evolution and adaptationThe Drosophila synaptotagmin-like protein bitesize is required for growth and has mRNA localization sequences within its open reading frame.Pancreatic beta-cell protein granuphilin binds Rab3 and Munc-18 and controls exocytosis.Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells.Synaptotagmin-like protein (Slp) homology domain 1 of Slac2-a/melanophilin is a critical determinant of GTP-dependent specific binding to Rab27A.Rab GTPases and myosin motors in organelle motility.Dysregulation of gene expression as a cause of Cockayne syndrome neurological disease.Involvement of the Rab27 binding protein Slac2c/MyRIP in insulin exocytosis.Rab27 effectors, pleiotropic regulators in secretory pathways.The C2A domain of synaptotagmin-like protein 3 (Slp3) is an atypical calcium-dependent phospholipid-binding machine: comparison with the C2A domain of synaptotagmin I.Vesicle-associated membrane protein-2/synaptobrevin binding to synaptotagmin I promotes O-glycosylation of synaptotagmin I.Formation of crystalloid endoplasmic reticulum induced by expression of synaptotagmin lacking the conserved WHXL motif in the C terminus. Structural importance of the WHXL motif in the C2B domain.The actin-binding domain of Slac2-a/melanophilin is required for melanosome distribution in melanocytesA genome-wide analysis of brain DNA methylation identifies new candidate genes for sporadic amyotrophic lateral sclerosis.Akt regulates the subcellular localization of the Rab27a-binding protein JFC1 by phosphorylation.The C2 domains of granuphilin are high-affinity sensors for plasma membrane lipids.The Slp4-a linker domain controls exocytosis through interaction with Munc18-1.syntaxin-1a complex.Functional analysis of Slac2-c/MyRIP as a linker protein between melanosomes and myosin VIIa.Slp4-a/granuphilin-a interacts with syntaxin-2/3 in a Munc18-2-dependent manner.The C2A domain of double C2 protein gamma contains a functional nuclear localization signal.Effect of ovarian cancer ascites on SKOV-3 cells proteome: new proteins associated with aggressive phenotype in epithelial ovarian cancer.
P2860
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P2860
Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins
@ast
Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins
@en
Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins
@nl
type
label
Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins
@ast
Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins
@en
Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins
@nl
prefLabel
Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins
@ast
Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins
@en
Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins
@nl
P356
P1476
Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins
@en
P2093
P304
P356
10.1006/BBRC.2001.4512
P407
P577
2001-03-01T00:00:00Z