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A peripheral element assembles the compact core structure essential for group I intron self-splicing.Progress and Prospects of Anti-HBV Gene Therapy DevelopmentSingle molecule fluorescence approaches shed light on intracellular RNAsRNA tectonics (tectoRNA) for RNA nanostructure design and its application in synthetic biologyA comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilizationStructural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozymeNMR structure of a 4 x 4 nucleotide RNA internal loop from an R2 retrotransposon: Identification of a three purine-purine sheared pair motif and comparison to MC-SYM predictionsWater in the active site of an all-RNA hairpin ribozyme and effects of Gua8 base variants on the geometry of phosphoryl transferStructural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAsEvolutionary evidence for alternative structure in RNA sequence co-variationThe Astrobiology Primer v2.0Theory of the origin, evolution, and nature of lifeWhat contemporary viruses tell us about evolution: a personal viewSharing and archiving nucleic acid structure mapping dataFunctional nucleic acid sensorsDiscovering cis-regulatory RNAs in Shewanella genomes by Support Vector MachinesCounting the ions surrounding nucleic acids.CHARMM force field parameters for simulation of reactive intermediates in native and thio-substituted ribozymesEvidence for the role of active site residues in the hairpin ribozyme from molecular simulations along the reaction path.A divalent cation stabilizes the active conformation of the B. subtilis RNase P x pre-tRNA complex: a role for an inner-sphere metal ion in RNase P.ProbeAlign: incorporating high-throughput sequencing-based structure probing information into ncRNA homology search.Evaluating our ability to predict the structural disruption of RNA by SNPs.Dissection of a metal-ion-mediated conformational change in Tetrahymena ribozyme catalysisRNA-acting antibiotics: in-vitro selection of RNA aptamers for the design of new bioactive molecules less susceptible to bacterial resistance.Hammerhead ribozymes for target validation.Functional tuning of nucleic acids by chemical modifications: tailored oligonucleotides as drugs, devices, and diagnostics.Coplanar and coaxial orientations of RNA bases and helices.Thermodynamic examination of 1- to 5-nt purine bulge loops in RNA and DNA constructs.Coupling of fast and slow modes in the reaction pathway of the minimal hammerhead ribozyme cleavage.Dual control system - A novel scaffolding architecture of an inducible regulatory device for the precise regulation of gene expressionDevelopment of lead hammerhead ribozyme candidates against human rod opsin mRNA for retinal degeneration therapy.Predicting 3D Structure, Flexibility, and Stability of RNA Hairpins in Monovalent and Divalent Ion SolutionsCan gene delivery close the door to HIV-1 entry after escape?Bridging the gap between theory and experiment to derive a detailed understanding of hammerhead ribozyme catalysis.Ab initio RNA folding by discrete molecular dynamics: from structure prediction to folding mechanismsElectrostatic interactions in the hairpin ribozyme account for the majority of the rate acceleration without chemical participation by nucleobasesInformatics challenges in structured RNA.Role of Mg2+ in hammerhead ribozyme catalysis from molecular simulationRibozyme Catalysis with a Twist: Active State of the Twister Ribozyme in Solution Predicted from Molecular Simulation.Insight into the role of Mg in hammerhead ribozyme catalysis from X-ray crystallography and molecular dynamics simulation.
P2860
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P2860
description
2001 nî lūn-bûn
@nan
2001 թուականին հրատարակուած գիտական յօդուած
@hyw
2001 թվականին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Ribozyme structures and mechanisms
@ast
Ribozyme structures and mechanisms
@en
Ribozyme structures and mechanisms
@nl
type
label
Ribozyme structures and mechanisms
@ast
Ribozyme structures and mechanisms
@en
Ribozyme structures and mechanisms
@nl
prefLabel
Ribozyme structures and mechanisms
@ast
Ribozyme structures and mechanisms
@en
Ribozyme structures and mechanisms
@nl
P3181
P1476
Ribozyme structures and mechanisms
@en
P2093
E A Doherty
P304
P3181
P356
10.1146/ANNUREV.BIOPHYS.30.1.457
P407
P577
2001-01-01T00:00:00Z