DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1
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The NEDD8 modification pathway in plantsCharacterization of the human COP9 signalosome complex using affinity purification and mass spectrometryStructural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1.The structure of SENP1-SUMO-2 complex suggests a structural basis for discrimination between SUMO paralogues during processingSUMO protease SENP1 induces isomerization of the scissile peptide bondAdenosine and hypoxia-inducible factor signaling in intestinal injury and recoveryRegulation and cellular roles of ubiquitin-specific deubiquitinating enzymesSUSP1 antagonizes formation of highly SUMO2/3-conjugated speciesThe Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and RepairOptimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblottingNeutrophils and inflammatory resolution in the mucosaFunction and regulation of SUMO proteasesThe DenA/DEN1 Interacting Phosphatase DipA Controls Septa Positioning and Phosphorylation-Dependent Stability of Cytoplasmatic DenA/DEN1 during Fungal DevelopmentStructure of the Human SENP7 Catalytic Domain and Poly-SUMO Deconjugation Activities for SENP6 and SENP7Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1Actions of adenosine on cullin neddylation: implications for inflammatory responsesCharacterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3.The SUMO-specific protease SENP5 is required for cell division.Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs.Identification and characterization of DEN1, a deneddylase of the ULP familyTbata modulates thymic stromal cell proliferation and thymus functionContributions of neutrophils to resolution of mucosal inflammation.The molecular determinants for distinguishing between ubiquitin and NEDD8 by USP2.The essential functions of NEDD8 are mediated via distinct surface regions, and not by polyneddylation in Schizosaccharomyces pombe.Nedd8 on cullin: building an expressway to protein destruction.Protein neddylation: beyond cullin-RING ligases.The molecular determinants of NEDD8 specific recognition by human SENP8.COPing with hypoxiaThe NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and Therapy.Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins.Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapyControl of multicellular development by the physically interacting deneddylases DEN1/DenA and COP9 signalosome.Brap2 regulates temporal control of NF-κB localization mediated by inflammatory response.Stabilization of HIF through inhibition of Cullin-2 neddylation is protective in mucosal inflammatory responsesNeddylation and deneddylation in cardiac biologyAnti-inflammatory actions of adrenomedullin through fine tuning of HIF stabilization.Mono-ubiquitination drives nuclear export of the human DCN1-like protein hDCNL1Dissecting the ubiquitin pathway by mass spectrometry.Implications of protein post-translational modifications in IBD.Deconjugation of Nedd8 from Cul1 is directly regulated by Skp1-F-box and substrate, and the COP9 signalosome inhibits deneddylated SCF by a noncatalytic mechanism.
P2860
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P2860
DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
DEN1 is a dual function protea ...... jugating hyper-neddylated CUL1
@ast
DEN1 is a dual function protea ...... jugating hyper-neddylated CUL1
@en
DEN1 is a dual function protea ...... jugating hyper-neddylated CUL1
@nl
type
label
DEN1 is a dual function protea ...... jugating hyper-neddylated CUL1
@ast
DEN1 is a dual function protea ...... jugating hyper-neddylated CUL1
@en
DEN1 is a dual function protea ...... jugating hyper-neddylated CUL1
@nl
prefLabel
DEN1 is a dual function protea ...... jugating hyper-neddylated CUL1
@ast
DEN1 is a dual function protea ...... jugating hyper-neddylated CUL1
@en
DEN1 is a dual function protea ...... jugating hyper-neddylated CUL1
@nl
P2093
P2860
P3181
P356
P1476
DEN1 is a dual function protea ...... jugating hyper-neddylated CUL1
@en
P2093
Angus Chen
Chee-Gun Lee
Georgia Dolios
Keith D Wilkinson
Kenneth Wu
Kosj Yamoah
Peilin Tan
Tudeviin Gan-Erdene
P2860
P304
P3181
P356
10.1074/JBC.M302888200
P407
P577
2003-08-01T00:00:00Z