Human carboxylesterase 1: from drug metabolism to drug discovery
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Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basisProtein adducts as biomarkers of exposure to organophosphorus compoundsThe novel carboxylesterase 1 variant c.662A>G may decrease the bioactivation of oseltamivir in humansThe effect of ethanol on oral cocaine pharmacokinetics reveals an unrecognized class of ethanol-mediated drug interactions.Developing a vaccine against multiple psychoactive targets: a case study of heroin.The role of human carboxylesterases in drug metabolism: have we overlooked their importance?Lower serum hepcidin and greater parenchymal iron in nonalcoholic fatty liver disease patients with C282Y HFE mutations.A simple nonradioactive method for the determination of the binding affinities of antibodies induced by hapten bioconjugates for drugs of abuseInhibition of polyisoprenylated methylated protein methyl esterase by synthetic musks induces cell degeneration.Association between copy number variation losses and alcohol dependence across African American and European American ethnic groups.Carboxylesterase inhibitors.Selective Inhibitors of Human Liver Carboxylesterase Based on a β-Lapachone Scaffold: Novel Reagents for Reaction Profiling.Effects of toxicologically relevant xenobiotics and the lipid-derived electrophile 4-hydroxynonenal on macrophage cholesterol efflux: silencing carboxylesterase 1 has paradoxical effects on cholesterol uptake and efflux.Analysis of the inhibition of mammalian carboxylesterases by novel fluorobenzoins and fluorobenzils.Immobilization of active human carboxylesterase 1 in biomimetic silica nanoparticles.Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1.Undesired versus designed enzymatic cleavage of linkers for liver targetingInhibition of human carboxylesterases hCE1 and hiCE by cholinesterase inhibitors.Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxylesterase inhibition using classical and 3D-quantitative structure-activity relationship analysis.Liver prenylated methylated protein methyl esterase is the same enzyme as Sus scrofa carboxylesterase.Stem cell-ness: a "magic marker" for cancer.The Alpha-2A Adrenergic Receptor Gene -1291C/G Single Nucleotide Polymorphism is Associated with the Efficacy of Methylphenidate in Treating Taiwanese Children and Adolescents with Attention-Deficit Hyperactivity Disorder.Left Atrial Appendage Thrombus Formation in a Patient on Dabigatran Therapy Associated With ABCB1 and CES-1 Genetic Defect.
P2860
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P2860
Human carboxylesterase 1: from drug metabolism to drug discovery
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Human carboxylesterase 1: from drug metabolism to drug discovery
@ast
Human carboxylesterase 1: from drug metabolism to drug discovery
@en
Human carboxylesterase 1: from drug metabolism to drug discovery
@nl
type
label
Human carboxylesterase 1: from drug metabolism to drug discovery
@ast
Human carboxylesterase 1: from drug metabolism to drug discovery
@en
Human carboxylesterase 1: from drug metabolism to drug discovery
@nl
prefLabel
Human carboxylesterase 1: from drug metabolism to drug discovery
@ast
Human carboxylesterase 1: from drug metabolism to drug discovery
@en
Human carboxylesterase 1: from drug metabolism to drug discovery
@nl
P2093
P1476
Human carboxylesterase 1: from drug metabolism to drug discovery
@en
P2093
M R Redinbo
P M Potter
S Bencharit
P407
P577
2003-06-01T00:00:00Z