Role of Dok1 in cell signaling mediated by RET tyrosine kinase
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The unique N-terminal region of SRMS regulates enzymatic activity and phosphorylation of its novel substrate docking protein 1Interaction of SH2-Bbeta with RET is involved in signaling of GDNF-induced neurite outgrowthStructural basis for the specific recognition of RET by the Dok1 phosphotyrosine binding domainc-Abl phosphorylates Dok1 to promote filopodia during cell spreadingNck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress.PAK1-Nck regulates cyclin D1 promoter activity in response to prolactinScreening for PTB domain binding partners and ligand specificity using proteome-derived NPXY peptide arrays.Sumoylation modulates transcriptional activity of MITF in a promoter-specific mannerDOK1 mediates SHP-2 binding to the alphaVbeta3 integrin and thereby regulates insulin-like growth factor I signaling in cultured vascular smooth muscle cells.BRK targets Dok1 for ubiquitin-mediated proteasomal degradation to promote cell proliferation and migration.The RET proto-oncogene: a molecular therapeutic target in thyroid cancer.Regulation of neural development by glial cell line-derived neurotrophic factor family ligands.Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia.A targeting mutation of tyrosine 1062 in Ret causes a marked decrease of enteric neurons and renal hypoplasiaIkappaB kinase beta phosphorylates Dok1 serines in response to TNF, IL-1, or gamma radiation.XL184 (cabozantinib) for medullary thyroid carcinoma.The RET oncogene in papillary thyroid carcinoma.Characterization of DOK1, a candidate tumor suppressor gene, in epithelial ovarian cancer.Engineering the recruitment of phosphotyrosine binding domain-containing adaptor proteins reveals distinct roles for RET receptor-mediated cell survival.Evaluation of potential mechanisms underlying genotype-phenotype correlations in multiple endocrine neoplasia type 2.Dok-1 tyrosine residues at 336 and 340 are essential for the negative regulation of Ras-Erk signalling, but dispensable for rasGAP-binding.Pleckstrin homology and phosphotyrosine-binding domain-dependent membrane association and tyrosine phosphorylation of Dok-4, an inhibitory adapter molecule expressed in epithelial cells.
P2860
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P2860
Role of Dok1 in cell signaling mediated by RET tyrosine kinase
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2002 nî lūn-bûn
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2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
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name
Role of Dok1 in cell signaling mediated by RET tyrosine kinase
@ast
Role of Dok1 in cell signaling mediated by RET tyrosine kinase
@en
Role of Dok1 in cell signaling mediated by RET tyrosine kinase
@nl
type
label
Role of Dok1 in cell signaling mediated by RET tyrosine kinase
@ast
Role of Dok1 in cell signaling mediated by RET tyrosine kinase
@en
Role of Dok1 in cell signaling mediated by RET tyrosine kinase
@nl
prefLabel
Role of Dok1 in cell signaling mediated by RET tyrosine kinase
@ast
Role of Dok1 in cell signaling mediated by RET tyrosine kinase
@en
Role of Dok1 in cell signaling mediated by RET tyrosine kinase
@nl
P2093
P356
P1476
Role of Dok1 in cell signaling mediated by RET tyrosine kinase
@en
P2093
Hideki Murakami
Kei Kurokawa
Kumi Kawai
Masahide Takahashi
Yumiko Yamamura
P304
P356
10.1074/JBC.M202336200
P407
P577
2002-09-06T00:00:00Z