Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1
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Human miR-221/222 in Physiological and Atherosclerotic Vascular RemodelingRaf-interactome in tuning the complexity and diversity of Raf function.Calcium/calmodulin-dependent protein kinase II (CaMKII) phosphorylates Raf-1 at serine 338 and mediates Ras-stimulated Raf-1 activation.Regulation of Raf through phosphorylation and N terminus-C terminus interactionErbin suppresses the MAP kinase pathwayB-Raf and Raf-1 are regulated by distinct autoregulatory mechanismsPAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signalingA genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's diseaseRAF1-activated MEK1 is found on the Golgi apparatus in late prophase and is required for Golgi complex fragmentation in mitosisAdhesion stimulates direct PAK1/ERK2 association and leads to ERK-dependent PAK1 Thr212 phosphorylationPak1 as a novel therapeutic target for antihypertrophic treatment in the heartThe RAF proteins take centre stageLAT-independent Erk activation via Bam32-PLC-γ1-Pak1 complexes: GTPase-independent Pak1 activation.Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis.ADP-ribosylation factor 6 regulates tumor cell invasion through the activation of the MEK/ERK signaling pathwayLysophosphatidic acid induces MDA-MB-231 breast cancer cells migration through activation of PI3K/PAK1/ERK signaling.IL-6 increases MMP-13 expression and motility in human chondrosarcoma cells.Enterovirus 71 Proteins 2A and 3D Antagonize the Antiviral Activity of Gamma Interferon via Signaling Attenuation.Phosphatidylinositol-3-phosphate kinase pathway activation protects leukemic large granular lymphocytes from undergoing homeostatic apoptosis.An activating mutation in sos-1 identifies its Dbl domain as a critical inhibitor of the epidermal growth factor receptor pathway during Caenorhabditis elegans vulval development.Kinase-independent role for CRAF-driving tumour radioresistance via CHK2PAK1 is a novel MEK-independent raf target controlling expression of the IAP survivin in M-CSF-mediated osteoclast survivalPathway crosstalk between Ras/Raf and PI3K in promotion of M-CSF-induced MEK/ERK-mediated osteoclast survivalRegulation of tamoxifen sensitivity by a PAK1-EBP1 signalling pathway in breast cancer.p21 activated kinase 5 activates Raf-1 and targets it to mitochondriaAKT upregulates B-Raf Ser445 phosphorylation and ERK1/2 activation in prostate cancer cells in response to androgen depletion.PI3K-dependent cross-talk interactions converge with Ras as quantifiable inputs integrated by ErkProlactin-induced PAK1 tyrosyl phosphorylation promotes FAK dephosphorylation, breast cancer cell motility, invasion and metastasis.Pak protein kinases and their role in cancer.Ras and extracellular signal-regulated kinase signaling in thymocytes and T cells.Mechanistic principles of RAF kinase signaling.IQGAP1: a regulator of intracellular spacetime relativity.PAK signaling in cancer.IQGAP1: insights into the function of a molecular puppeteer.Mice Deficient in lysophosphatidic acid acyltransferase delta (Lpaatδ)/acylglycerophosphate acyltransferase 4 (Agpat4) Have Impaired Learning and Memory.P21-activated kinase 1 (PAK1) as a therapeutic target in BRAF wild-type melanoma.PAK1-dependent MAPK pathway activation is required for colorectal cancer cell proliferation.Effects of rho kinase and actin stress fibers on sustained extracellular signal-regulated kinase activity and activation of G(1) phase cyclin-dependent kinases.The integrin-binding protein Nischarin regulates cell migration by inhibiting PAK.SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase.
P2860
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P2860
Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Interaction between active Pak ...... lation and activation of Raf-1
@ast
Interaction between active Pak ...... lation and activation of Raf-1
@en
Interaction between active Pak ...... lation and activation of Raf-1
@nl
type
label
Interaction between active Pak ...... lation and activation of Raf-1
@ast
Interaction between active Pak ...... lation and activation of Raf-1
@en
Interaction between active Pak ...... lation and activation of Raf-1
@nl
prefLabel
Interaction between active Pak ...... lation and activation of Raf-1
@ast
Interaction between active Pak ...... lation and activation of Raf-1
@en
Interaction between active Pak ...... lation and activation of Raf-1
@nl
P2860
P3181
P356
P1476
Interaction between active Pak ...... lation and activation of Raf-1
@en
P2093
Cynthia Hayne
P2860
P304
P3181
P356
10.1074/JBC.M110000200
P407
P577
2001-11-30T00:00:00Z