Involvement of the putative hematopoietic transcription factor SCL in T-cell acute lymphoblastic leukemia
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The SCL gene product: a positive regulator of erythroid differentiationFormation of in vivo complexes between the TAL1 and E2A polypeptides of leukemic T cellsThe LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cellsSpecific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemiaDiscovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancyAbsence of yolk sac hematopoiesis from mice with a targeted disruption of the scl geneMurine models of acute leukemia: important tools in current pediatric leukemia research.Homo-binding character of LMO2 isoforms and their both synergic and antagonistic functions in regulating hematopoietic-related target genes.Chromatin immunoselection defines a TAL-1 target geneMolecular diagnostic approach to non-Hodgkin's lymphoma.SIL-TAL1 rearrangement is related with poor outcome: a study from a Chinese institution.Cre-loxP-mediated recombination between the SIL and SCL genes leads to a block in T-cell development at the CD4- CD8- to CD4+ CD8+ transition.Protein dimerization between Lmo2 (Rbtn2) and Tal1 alters thymocyte development and potentiates T cell tumorigenesis in transgenic miceIllegitimate V(D)J recombination involving nonantigen receptor loci in lymphoid malignancy.The partial tandem duplication of ALL1 in acute myeloid leukemia with normal cytogenetics or trisomy 11 is restricted to one chromosome.A third tal-1 promoter is specifically used in human T cell leukemiasDisruption of the SCL gene by a t(1;3) translocation in a patient with T cell acute lymphoblastic leukemia.T-cell acute leukemia 1 (TAL1) regulation of erythropoietin receptor and association with excessive erythrocytosis.Aberrant V(D)J recombination is not required for rapid development of H2ax/p53-deficient thymic lymphomas with clonal translocations.Cross talk between expression of the human T-cell leukemia virus type 1 Tax transactivator and the oncogenic bHLH transcription factor TAL1.microRNAs regulate TAL1 expression in T-cell acute lymphoblastic leukemiaTargeting the Notch1 and mTOR pathways in a mouse T-ALL model.LMO2 attenuates tumor growth by targeting the Wnt signaling pathway in breast and colorectal cancer.Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma.Loss of TAL-1 protein activity induces premature apoptosis of Jurkat leukemic T cells upon medium depletionBreakpoint sites disclose the role of the V(D)J recombination machinery in the formation of T-cell receptor (TCR) and non-TCR associated aberrations in T-cell acute lymphoblastic leukemia.Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes.STIL balancing primary microcephaly and cancer.Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia.The proto-oncogenic protein TAL1 controls TGF-β1 signaling through interaction with SMAD3.
P2860
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P2860
Involvement of the putative hematopoietic transcription factor SCL in T-cell acute lymphoblastic leukemia
description
1992 nî lūn-bûn
@nan
1992 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի մարտին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Involvement of the putative he ...... l acute lymphoblastic leukemia
@ast
Involvement of the putative he ...... l acute lymphoblastic leukemia
@en
Involvement of the putative he ...... l acute lymphoblastic leukemia
@nl
type
label
Involvement of the putative he ...... l acute lymphoblastic leukemia
@ast
Involvement of the putative he ...... l acute lymphoblastic leukemia
@en
Involvement of the putative he ...... l acute lymphoblastic leukemia
@nl
prefLabel
Involvement of the putative he ...... l acute lymphoblastic leukemia
@ast
Involvement of the putative he ...... l acute lymphoblastic leukemia
@en
Involvement of the putative he ...... l acute lymphoblastic leukemia
@nl
P2093
P3181
P1433
P1476
Involvement of the putative he ...... l acute lymphoblastic leukemia
@en
P2093
D P Lombardi
G D Hammond
G H Reaman
H N Sather
I R Kirsch
P304
P3181
P407
P577
1992-03-01T00:00:00Z