The SCL gene product: a positive regulator of erythroid differentiation
about
ABC-me: a novel mitochondrial transporter induced by GATA-1 during erythroid differentiationThe LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiationCloning and characterization of a basic helix-loop-helix protein expressed in early mesoderm and the developing somitesmSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factorThe LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cellsSpecific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemiaNeuroD1/beta2 contributes to cell-specific transcription of the proopiomelanocortin geneHelix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cellsOLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1Expression of a CALM-AF10 fusion gene leads to Hoxa cluster overexpression and acute leukemia in transgenic miceEto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitorsThe scl gene product is required for the generation of all hematopoietic lineages in the adult mouseAbsence of yolk sac hematopoiesis from mice with a targeted disruption of the scl geneDistinct functions for different scl isoforms in zebrafish primitive and definitive hematopoiesisChromatin immunoselection defines a TAL-1 target geneSpecific protein-protein interaction between basic helix-loop-helix transcription factors and homeoproteins of the Pitx family.Conditional expression of the ubiquitous transcription factor MafK induces erythroleukemia cell differentiation.Notch1 mutations are important for leukemic transformation in murine models of precursor-T leukemia/lymphomaDynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis.P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor TAL1/SCLTranscription factor networks in erythroid cell and megakaryocyte developmentBone marrow transcriptome and epigenome profiles of equine common variable immunodeficiency patients unveil block of B lymphocyte differentiation.Identification of a TAL1 target gene reveals a positive role for the LIM domain-binding protein Ldb1 in erythroid gene expression and differentiation.Regulation of the stem cell leukemia (SCL) gene: a tale of two fishesTranscription factor SCL is required for c-kit expression and c-Kit function in hemopoietic cells.The SCL gene product is regulated by and differentially regulates cytokine responses during myeloid leukemic cell differentiation.BETA3, a novel helix-loop-helix protein, can act as a negative regulator of BETA2 and MyoD-responsive genes.Functional analysis of the V gamma 3 promoter of the murine gamma delta T-cell receptorInduction of erythroid-specific gene expression in lymphoid cellsInhibition of all-trans retinoic acid-induced granulocytic differentiation of WEHI-3B D+ cells by forced expression of SCL (TAL1) and GATA-1.Genetic interaction between Kit and Scl.Loss of TAL-1 protein activity induces premature apoptosis of Jurkat leukemic T cells upon medium depletionThe hematopoietic regulator TAL1 is required for chromatin looping between the β-globin LCR and human γ-globin genes to activate transcription.Deletion of Stk40 impairs definitive erythropoiesis in the mouse fetal liver.ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesis.Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins Sp1 and EKLF.Differences between MyoD DNA binding and activation site requirements revealed by functional random sequence selection.Ectopic TAL-1/SCL expression in phenotypically normal or leukemic myeloid precursors: proliferative and antiapoptotic effects coupled with a differentiation blockade.SCL assembles a multifactorial complex that determines glycophorin A expression.Impaired in vitro erythropoiesis following deletion of the Scl (Tal1) +40 enhancer is largely compensated for in vivo despite a significant reduction in expression
P2860
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P2860
The SCL gene product: a positive regulator of erythroid differentiation
description
1992 nî lūn-bûn
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1992 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի նոյեմբերին հրատարակված գիտական հոդված
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1992年の論文
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1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
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name
The SCL gene product: a positive regulator of erythroid differentiation
@ast
The SCL gene product: a positive regulator of erythroid differentiation
@en
The SCL gene product: a positive regulator of erythroid differentiation
@en-gb
The SCL gene product: a positive regulator of erythroid differentiation
@nl
type
label
The SCL gene product: a positive regulator of erythroid differentiation
@ast
The SCL gene product: a positive regulator of erythroid differentiation
@en
The SCL gene product: a positive regulator of erythroid differentiation
@en-gb
The SCL gene product: a positive regulator of erythroid differentiation
@nl
prefLabel
The SCL gene product: a positive regulator of erythroid differentiation
@ast
The SCL gene product: a positive regulator of erythroid differentiation
@en
The SCL gene product: a positive regulator of erythroid differentiation
@en-gb
The SCL gene product: a positive regulator of erythroid differentiation
@nl
P2093
P2860
P1433
P1476
The SCL gene product: a positive regulator of erythroid differentiation
@en
P2093
P2860
P304
P407
P577
1992-11-01T00:00:00Z