A CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2
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The amino-terminal B-Raf-specific region mediates calcium-dependent homo- and hetero-dimerization of Raf.Small G proteins in the cardiovascular system: physiological and pathological aspectsCalDAG-GEFI integrates signaling for platelet aggregation and thrombus formationGuanine nucleotide exchange factors CalDAG-GEFI and CalDAG-GEFII are colocalized in striatal projection neuronsRap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-gamma1Rap1 GTPases: an emerging role in the cardiovasculatureG-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathwayRap1b in smooth muscle and endothelium is required for maintenance of vascular tone and normal blood pressure.PKA, Rap1, ERK1/2, and p90RSK mediate PGE2 and EP4 signaling in neonatal ventricular myocytes.CalDAG-GEFI down-regulation in the striatum as a neuroprotective change in Huntington's disease.Generation of cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate by CD38 for Ca2+ signaling in interleukin-8-treated lymphokine-activated killer cells.Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras.The emerging role of guanine nucleotide exchange factors in ALS and other neurodegenerative diseases.Basal Ganglia disorders associated with imbalances in the striatal striosome and matrix compartments.cAMP/PKA-mediated regulation of erythropoiesis.Up-regulation of interleukin-8 by novel small cytoplasmic molecules of nontypeable Haemophilus influenzae via p38 and extracellular signal-regulated kinase pathways.G protein regulation of MAPK networks.Structural Basis for the Failure of the C1 Domain of Ras Guanine Nucleotide Releasing Protein 2 (RasGRP2) to Bind Phorbol Ester with High Affinity.Dysregulation of CalDAG-GEFI and CalDAG-GEFII predicts the severity of motor side-effects induced by anti-parkinsonian therapyRasGRP3, a Ras activator, contributes to signaling and the tumorigenic phenotype in human melanoma.Extracellular calcium elicits feedforward regulation of the Toll-like receptor-triggered innate immune response.RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma.Intracellular distribution of functional M(1) -muscarinic acetylcholine receptors in N1E-115 neuroblastoma cells.Distinct pathways of ERK activation by the muscarinic agonists pilocarpine and carbachol in a human salivary cell line.Differential membrane binding and diacylglycerol recognition by C1 domains of RasGRPs.Enhancement of serum- and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/poliovirus receptor/CD155 through the Ras-Raf-MEK-ERK signaling.Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway.Rap1 activation plays a regulatory role in pancreatic amylase secretion.Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes.Serum response factor activation by muscarinic receptors via RhoA. Novel pathway specific to M1 subtype involving calmodulin, calcineurin, and Pyk2.Transformation potency of ErbB heterodimer signaling is determined by B-Raf kinase.Epac-Rap1-activated mesenchymal stem cells improve cardiac function in rat model of myocardial infarction.Modulation of Gq-Rho Signaling by the ERK MAPK Pathway Controls Locomotion in Caenorhabditis elegans.
P2860
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P2860
A CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
A CalDAG-GEFI/Rap1/B-Raf casse ...... rs to the activation of ERK1/2
@ast
A CalDAG-GEFI/Rap1/B-Raf casse ...... rs to the activation of ERK1/2
@en
A CalDAG-GEFI/Rap1/B-Raf casse ...... rs to the activation of ERK1/2
@nl
type
label
A CalDAG-GEFI/Rap1/B-Raf casse ...... rs to the activation of ERK1/2
@ast
A CalDAG-GEFI/Rap1/B-Raf casse ...... rs to the activation of ERK1/2
@en
A CalDAG-GEFI/Rap1/B-Raf casse ...... rs to the activation of ERK1/2
@nl
prefLabel
A CalDAG-GEFI/Rap1/B-Raf casse ...... rs to the activation of ERK1/2
@ast
A CalDAG-GEFI/Rap1/B-Raf casse ...... rs to the activation of ERK1/2
@en
A CalDAG-GEFI/Rap1/B-Raf casse ...... rs to the activation of ERK1/2
@nl
P2093
P2860
P356
P1476
A CalDAG-GEFI/Rap1/B-Raf casse ...... rs to the activation of ERK1/2
@en
P2093
P2860
P304
P356
10.1074/JBC.M101277200
P407
P577
2001-07-06T00:00:00Z