RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans
about
Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3Mechanism of regulation of the Epac family of cAMP-dependent RapGEFsIdentification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interactionMembrane-associated guanylate kinase with inverted orientation (MAGI)-1/brain angiogenesis inhibitor 1-associated protein (BAP1) as a scaffolding molecule for Rap small G protein GDP/GTP exchange protein at tight junctionsRA-GEF-1, a guanine nucleotide exchange factor for Rap1, is activated by translocation induced by association with Rap1*GTP and enhances Rap1-dependent B-Raf activationNedd4 regulates ubiquitination and stability of the guanine-nucleotide exchange factor CNrasGEFA novel binding protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5The guanine nucleotide exchange factor CNrasGEF regulates melanogenesis and cell survival in melanoma cellsRapgef2 connects GPCR-mediated cAMP signals to ERK activation in neuronal and endocrine cellsThe Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeletonDirect binding of the beta1 adrenergic receptor to the cyclic AMP-dependent guanine nucleotide exchange factor CNrasGEF leads to Ras activationRap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowthRGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphaoThe M-Ras-RA-GEF-2-Rap1 pathway mediates tumor necrosis factor-alpha dependent regulation of integrin activation in splenocytesA CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesisRequirement for Plk2 in orchestrated ras and rap signaling, homeostatic structural plasticity, and memoryCritical function of the Ras-associating domain as a primary Ras-binding site for regulation of Saccharomyces cerevisiae adenylyl cyclase.Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortexDrosophila PDZ-GEF, a guanine nucleotide exchange factor for Rap1 GTPase, reveals a novel upstream regulatory mechanism in the mitogen-activated protein kinase signaling pathway.Novel Rap1 dominant-negative mutants interfere selectively with C3G and Epac.PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis.Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP.Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.Search for new cyclic AMP-binding proteins.Connecdenn 3/DENND1C binds actin linking Rab35 activation to the actin cytoskeleton.Crucial Role of Rapgef2 and Rapgef6, a Family of Guanine Nucleotide Exchange Factors for Rap1 Small GTPase, in Formation of Apical Surface Adherens Junctions and Neural Progenitor Development in the Mouse Cerebral CortexE-cadherin dis-engagement activates the Rap1 GTPase.Two steps forward--one step back: advances in affinity purification mass spectrometry of macromolecular complexes.Distinct functions for Rap1 signaling in vascular morphogenesis and dysfunction.The connecdenn family, Rab35 guanine nucleotide exchange factors interfacing with the clathrin machinery.Requirement of the Caenorhabditis elegans RapGEF pxf-1 and rap-1 for epithelial integrityCalDAG-GEFIII activation of Ras, R-ras, and Rap1.NCS-Rapgef2, the Protein Product of the Neuronal Rapgef2 Gene, Is a Specific Activator of D1 Dopamine Receptor-Dependent ERK Phosphorylation in Mouse Brain.Plk2 Raps up Ras to subdue synapses.BAG3 directly associates with guanine nucleotide exchange factor of Rap1, PDZGEF2, and regulates cell adhesion.Protein Kinase A-independent Ras Protein Activation Cooperates with Rap1 Protein to Mediate Activation of the Extracellular Signal-regulated Kinases (ERK) by cAMP.Epac-inhibitors: facts and artefacts.Comprehensive behavioral analysis of mice deficient in Rapgef2 and Rapgef6, a subfamily of guanine nucleotide exchange factors for Rap small GTPases possessing the Ras/Rap-associating domain.A systems-wide screen identifies substrates of the SCF TrCP ubiquitin ligase
P2860
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P2860
RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
RA-GEF, a novel Rap1A guanine ...... ed between nematode and humans
@ast
RA-GEF, a novel Rap1A guanine ...... ed between nematode and humans
@en
RA-GEF, a novel Rap1A guanine ...... ed between nematode and humans
@en-gb
RA-GEF, a novel Rap1A guanine ...... ed between nematode and humans
@nl
type
label
RA-GEF, a novel Rap1A guanine ...... ed between nematode and humans
@ast
RA-GEF, a novel Rap1A guanine ...... ed between nematode and humans
@en
RA-GEF, a novel Rap1A guanine ...... ed between nematode and humans
@en-gb
RA-GEF, a novel Rap1A guanine ...... ed between nematode and humans
@nl
prefLabel
RA-GEF, a novel Rap1A guanine ...... ed between nematode and humans
@ast
RA-GEF, a novel Rap1A guanine ...... ed between nematode and humans
@en
RA-GEF, a novel Rap1A guanine ...... ed between nematode and humans
@en-gb
RA-GEF, a novel Rap1A guanine ...... ed between nematode and humans
@nl
P2093
P2860
P3181
P356
P1476
RA-GEF, a novel Rap1A guanine ...... ed between nematode and humans
@en
P2093
M Shibatohge
P2860
P304
P3181
P356
10.1074/JBC.274.53.37815
P407
P577
1999-12-31T00:00:00Z