Induction of the mammalian node requires Arkadia function in the extraembryonic lineages
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Poly-small ubiquitin-like modifier (PolySUMO)-binding proteins identified through a string searchArkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signalingAxin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia.Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extensionArkadia amplifies TGF-beta superfamily signalling through degradation of Smad7Nodal morphogensSUMOylation target sites at the C terminus protect Axin from ubiquitination and confer protein stabilityArkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradationGene trap mutagenesis of hnRNP A2/B1: a cryptic 3' splice site in the neomycin resistance gene allows continued expression of the disrupted cellular geneInactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo.Regulation of TGF-β signal transduction by mono- and deubiquitylation of SmadsNMR-based insights into the conformational and interaction properties of Arkadia RING-H2 E3 Ub ligaseArkadia enhances nodal-related signalling to induce mesendodermCell fate decisions within the mouse organizer are governed by graded Nodal signalsArkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover.Induction of Ski Protein Expression upon Luteinization in Rat Granulosa Cells.Multiple Arkadia/RNF111 structures coordinate its Polycomb body association and transcriptional control.Enhancement of TGF-β signaling responses by the E3 ubiquitin ligase Arkadia provides tumor suppression in colorectal cancer.Neural induction and neural stem cell development.RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage responseRegulation of TGF-beta family signaling by E3 ubiquitin ligases.c-Ski, Smurf2, and Arkadia as regulators of TGF-beta signaling: new targets for managing myofibroblast function and cardiac fibrosis.Regulation of the transforming growth factor β pathway by reversible ubiquitylation.RB1CC1 protein positively regulates transforming growth factor-beta signaling through the modulation of Arkadia E3 ubiquitin ligase activity.SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair.Regulation of TGF-β Family Signaling by Inhibitory Smads.Identification of a novel protein interaction motif in the regulatory subunit of casein kinase 2.Arkadia, a novel SUMO-targeted ubiquitin ligase involved in PML degradation.The SMAD2/3 corepressor SNON maintains pluripotency through selective repression of mesendodermal genes in human ES cells.Zinc Binding Properties of Engineered RING Finger Domain of Arkadia E3 Ubiquitin LigaseActivation of epiblast gene expression by the hypoblast layer in the prestreak chick embryo.Breast cancer metastasis suppressor OTUD1 deubiquitinates SMAD7.Zic2 mutation causes holoprosencephaly via disruption of NODAL signalling.Molecular regulation of Nodal signaling during mesendoderm formation.Arkadia--beyond the TGF-β pathway.Ubiquitination and deubiquitination emerge as players in idiopathic pulmonary fibrosis pathogenesis and treatment.Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-β signallingUbiquitin conjugation system for body axes specification in vertebrates
P2860
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P2860
Induction of the mammalian node requires Arkadia function in the extraembryonic lineages
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Induction of the mammalian node requires Arkadia function in the extraembryonic lineages
@ast
Induction of the mammalian node requires Arkadia function in the extraembryonic lineages
@en
Induction of the mammalian node requires Arkadia function in the extraembryonic lineages
@nl
type
label
Induction of the mammalian node requires Arkadia function in the extraembryonic lineages
@ast
Induction of the mammalian node requires Arkadia function in the extraembryonic lineages
@en
Induction of the mammalian node requires Arkadia function in the extraembryonic lineages
@nl
prefLabel
Induction of the mammalian node requires Arkadia function in the extraembryonic lineages
@ast
Induction of the mammalian node requires Arkadia function in the extraembryonic lineages
@en
Induction of the mammalian node requires Arkadia function in the extraembryonic lineages
@nl
P2093
P2860
P356
P1433
P1476
Induction of the mammalian node requires Arkadia function in the extraembryonic lineages
@en
P2093
P M Timmons
R L Andrew
V Episkopou
P2860
P2888
P304
P356
10.1038/35071095
P407
P577
2001-04-12T00:00:00Z
P5875
P6179
1044917831