Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis
about
sameAs
Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic functionIdentification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosisThe permeability transition pore triggers Bax translocation to mitochondria during neuronal apoptosisRibosomal protein S3, a new substrate of Akt, serves as a signal mediator between neuronal apoptosis and DNA repairMutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arseniteThe Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinaseJNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosisThe BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cellsGene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathwayThe NF-kappaB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cellsIn vitro and in vivo assays for osteoclast apoptosisThe Importance of Thrombin in Cerebral Injury and DiseaseRegulation of Bim in Health and DiseaseDirect addition of BimL to mitochondria does not lead to cytochrome c releaseMolecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 familyFKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cellsFunctional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferationDamage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate.BIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cellsIntrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant miceConstitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cellsTemporal profiles of the subcellular localization of Bim, a BH3-only protein, during middle cerebral artery occlusion in miceSignaling by the kinase MINK is essential in the negative selection of autoreactive thymocytesConcomitant loss of proapoptotic BH3-only Bcl-2 antagonists Bik and Bim arrests spermatogenesisdp5/HRK is a c-Jun target gene and required for apoptosis induced by potassium deprivation in cerebellar granule neuronsNerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylationBag1-L is a phosphorylation-dependent coactivator of c-Jun during neuronal apoptosis.p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BADSystems genetic analysis of hippocampal neuroanatomy and spatial learning in mice.Afferent deprivation elicits a transcriptional response associated with neuronal survival after a critical period in the mouse cochlear nucleusN-cadherin mediates neuronal cell survival through Bim down-regulation.Increase in Bcl-2 phosphorylation and reduced levels of BH3-only Bcl-2 family proteins in kainic acid-mediated neuronal death in the rat brain.JNK inhibitory kinase is up-regulated in retinal ganglion cells after axotomy and enhances BimEL expression level in neuronal cells.Genetic control of programmed cell death during animal development.BH3-only proteins in rheumatoid arthritis: potential targets for therapeutic intervention.Gadd45a expression induces Bim dissociation from the cytoskeleton and translocation to mitochondria.The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase gammaVariations in the rheostat model of apoptosis: what studies of retinal ganglion cell death tell us about the functions of the Bcl2 family proteins.p75 neurotrophin receptor-mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up-regulation of tumor necrosis factor-alpha-converting enzyme/ADAM17.c-Jun mediates axotomy-induced dopamine neuron death in vivo.
P2860
Q24294552-E3665F2F-B641-4125-AEC6-39398332411CQ24296925-D5B15BC0-6C6B-4FCD-94BB-3751C5DFEBB5Q24337594-D8ACE305-C373-4BB2-A071-225D5C8B3B88Q24337831-4F240BC6-7A7C-4D58-9086-52CE5A9C4EC5Q24534853-DE8E2AA1-C9D3-40AF-955B-F083827999B2Q24537583-9197C5DF-4AD6-4205-A226-BEBC46F810E6Q24554008-901AC2A9-A128-416A-AFD6-A81760A849B4Q24650702-68C526AD-6836-451C-9BCD-6E91BD77664FQ24671908-B42C7C05-8239-42D3-8A96-64C6B5D906E5Q24676636-C7A1E716-D11B-4E0A-AB87-FBD80942BB8EQ24815945-EB3BEF07-FE77-4F3A-AFA1-F7DE9DBFFC75Q26772131-191EF151-B103-4E4A-B220-AA9D1399F706Q26781203-9FD615FA-99AE-4718-B0AE-E36F7AD7121AQ28208417-528CD426-0BE2-46C0-A0B9-1C1DBED55DA0Q28208950-A3968F4F-F216-4EB3-8F33-7F02C47E09A1Q28255883-E0F8416E-1576-49ED-AC33-DD65729821B9Q28285464-D06C0BAB-1A0F-44FC-96BB-173AC34C4532Q28364008-D87EEB03-70FC-45E7-B174-2CADD7E743D5Q28478390-C9F8BD73-1068-4368-9411-29DD38C48534Q28504500-DB28761E-AC79-447A-A917-8D63188856CDQ28505374-B766745D-186F-4D74-9F3C-DA3899598B1FQ28508507-B91C919A-6CDB-4BA8-9D2B-1A00B53ED286Q28510733-487D2637-F85B-4819-B2CF-62A6F825785CQ28511476-C63C8551-E3F4-4753-8ECD-654996E30DD3Q28565231-3F6188E0-7A60-4FAD-9DEA-C2844FA61900Q28576927-E863FB94-0885-4C61-BC7C-CF7F53A40B81Q28589005-10DF7F27-992A-4D6D-BCED-C8AF0F75A01EQ28592766-5D5BA2F5-88FF-45AD-AD18-75F9C414A87FQ30370298-D21BB23F-77B4-488C-8BCF-2DDD6534B625Q30490108-7464704C-2918-40F0-8631-6D6CD888842AQ31051374-89ACA780-A84C-41CB-B225-D947CE646230Q33188401-16FEF883-31EE-4413-A064-F39B8C31758BQ33221498-2F1B2F52-7F2D-45D7-922D-69F1D342A1F6Q33589613-3D5CBEC9-AE32-4EEF-A5A1-F33CAAB38A4FQ33727248-0915D91F-913B-423B-9537-46C5985586F7Q33837009-2E05F955-1C14-4E1D-9757-314128402DB5Q33876930-772905A7-72F4-470F-894D-5F3DF637659BQ33914559-E7DB3580-6608-4BB2-8CA3-1B6028889452Q33924464-63C5BCEA-B1CB-4393-A161-BFCAA9CE6E93Q33949411-8DE49E55-BC33-4EDD-BCBF-305A6731AF89
P2860
Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Induction of BIM, a proapoptot ...... ritical for neuronal apoptosis
@ast
Induction of BIM, a proapoptot ...... ritical for neuronal apoptosis
@en
Induction of BIM, a proapoptot ...... ritical for neuronal apoptosis
@nl
type
label
Induction of BIM, a proapoptot ...... ritical for neuronal apoptosis
@ast
Induction of BIM, a proapoptot ...... ritical for neuronal apoptosis
@en
Induction of BIM, a proapoptot ...... ritical for neuronal apoptosis
@nl
prefLabel
Induction of BIM, a proapoptot ...... ritical for neuronal apoptosis
@ast
Induction of BIM, a proapoptot ...... ritical for neuronal apoptosis
@en
Induction of BIM, a proapoptot ...... ritical for neuronal apoptosis
@nl
P2093
P50
P1433
P1476
Induction of BIM, a proapoptot ...... ritical for neuronal apoptosis
@en
P2093
E M Johnson
G V Putcha
J P Golden
K L Moulder
P304
P356
10.1016/S0896-6273(01)00238-0
P407
P577
2001-03-01T00:00:00Z