The WD motif-containing protein receptor for activated protein kinase C (RACK1) is required for recruitment and activation of signal transducer and activator of transcription 1 through the type I interferon receptor
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Protein kinase C epsilon-dependent regulation of cystic fibrosis transmembrane regulator involves binding to a receptor for activated C kinase (RACK1) and RACK1 binding to Na+/H+ exchange regulatory factorStructural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1RACK1, A multifaceted scaffolding protein: Structure and function.The RACK1 homologue from Trypanosoma brucei is required for the onset and progression of cytokinesis.Interferon induction and function at the mucosal surface.Comparative proteomic analysis of proliferating and functionally differentiated mammary epithelial cells.The phosphoproteome of bloodstream form Trypanosoma brucei, causative agent of African sleeping sicknessSolution structure of the human signaling protein RACK1.Asc1 supports cell-wall integrity near bud sites by a Pkc1 independent mechanismMumps virus V protein antagonizes interferon without the complete degradation of STAT1.The scaffolding protein RACK1 interacts with androgen receptor and promotes cross-talk through a protein kinase C signaling pathway.STAT3 activation by type I interferons is dependent on specific tyrosines located in the cytoplasmic domain of interferon receptor chain 2c. Activation of multiple STATS proceeds through the redundant usage of two tyrosine residues.Contribution of the Box 1 and Box 2 motifs of cytokine receptors to Jak1 association and activation.RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix.RACK1 recruits STAT3 specifically to insulin and insulin-like growth factor 1 receptors for activation, which is important for regulating anchorage-independent growth.Association of mumps virus V protein with RACK1 results in dissociation of STAT-1 from the alpha interferon receptor complex.Analytical use of multi-protein Fluorescence Resonance Energy Transfer to demonstrate membrane-facilitated interactions within cytokine receptor complexesRACK1 Function in Cell Motility and Protein Synthesis.Conventional protein kinase C inhibition prevents alpha interferon-mediated hepatitis C virus replicon clearance by impairing STAT activationPositive correlation of STAT1 and miR-146a with anemia in patients with systemic lupus erythematosus.RACK1 modulates NF-κB activation by interfering with the interaction between TRAF2 and the IKK complex.Elevated signal transducers and activators of transcription 1 correlates with increased C-C motif chemokine ligand 2 and C-X-C motif chemokine 10 levels in peripheral blood of patients with systemic lupus erythematosus.Multifarious determinants of cytokine receptor signaling specificity.RACK1, a versatile hub in cancer.The RNA-binding protein SERBP1 interacts selectively with the signaling protein RACK1.Role of a PDZ1 domain of NHERF1 in the binding of airway epithelial RACK1 to NHERF1.RACK1 regulates specific functions of Gbetagamma.Diptoindonesin G promotes ERK-mediated nuclear translocation of p-STAT1 (Ser727) and cell differentiation in AML cells.Receptor for activated C kinase 1 (RACK1) inhibits function of transient receptor potential (TRP)-type channel Pkd2L1 through physical interaction.The betagamma subunit of heterotrimeric G proteins interacts with RACK1 and two other WD repeat proteins.The anchoring protein RACK1 links protein kinase Cepsilon to integrin beta chains. Requirements for adhesion and motility.RACK1 is an insulin-like growth factor 1 (IGF-1) receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death.Cpc2/RACK1 is a ribosome-associated protein that promotes efficient translation in Schizosaccharomyces pombe.
P2860
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P2860
The WD motif-containing protein receptor for activated protein kinase C (RACK1) is required for recruitment and activation of signal transducer and activator of transcription 1 through the type I interferon receptor
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The WD motif-containing protei ...... the type I interferon receptor
@ast
The WD motif-containing protei ...... the type I interferon receptor
@en
The WD motif-containing protei ...... the type I interferon receptor
@nl
type
label
The WD motif-containing protei ...... the type I interferon receptor
@ast
The WD motif-containing protei ...... the type I interferon receptor
@en
The WD motif-containing protei ...... the type I interferon receptor
@nl
prefLabel
The WD motif-containing protei ...... the type I interferon receptor
@ast
The WD motif-containing protei ...... the type I interferon receptor
@en
The WD motif-containing protei ...... the type I interferon receptor
@nl
P2093
P2860
P356
P1476
The WD motif-containing protei ...... the type I interferon receptor
@en
P2093
A Usacheva
O Colamonici
R Minshall
P2860
P304
P356
10.1074/JBC.M100087200
P407
P577
2001-06-22T00:00:00Z