RACK1 recruits STAT3 specifically to insulin and insulin-like growth factor 1 receptors for activation, which is important for regulating anchorage-independent growth.
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Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advancesRegulation of receptor for activated C kinase 1 protein by the von Hippel-Lindau tumor suppressor in IGF-I-induced renal carcinoma cell invasivenessLyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cellsRACK1 and CIS mediate the degradation of BimEL in cancer cellsTargeting Protein Kinase C Downstream of Growth Factor and Adhesion SignallingThe role of prostate tumor overexpressed 1 in cancer progressionRACK1, A multifaceted scaffolding protein: Structure and function.RACK1, a new ADAM12 interacting protein. Contribution to liver fibrogenesis.The GAB2 signaling scaffold promotes anchorage independence and drives a transcriptional response associated with metastatic progression of breast cancer.Maize ZmRACK1 is involved in the plant response to fungal phytopathogensDcR3 binds to ovarian cancer via heparan sulfate proteoglycans and modulates tumor cells response to platinum with corresponding alteration in the expression of BRCA1.Overexpressions of RACK1 and CD147 associated with poor prognosis in stage T1 pulmonary adenocarcinoma.Leelamine mediates cancer cell death through inhibition of intracellular cholesterol transport.RACK1 identified as the PCBP1-interacting protein with a novel functional role on the regulation of human MOR gene expression.Receptor for activated protein kinase C1 regulates cell proliferation by modulating calcium signaling.The association of receptor of activated protein kinase C 1(RACK1) with infectious bursal disease virus viral protein VP5 and voltage-dependent anion channel 2 (VDAC2) inhibits apoptosis and enhances viral replication.Novel secondary somatic mutations in Ewing's sarcoma and desmoplastic small round cell tumorsTargeted therapies for advanced Ewing sarcoma family of tumors.Serine phosphorylation of the insulin-like growth factor I (IGF-1) receptor C-terminal tail restrains kinase activity and cell growthTargeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling.Deletion of Na+/H+ exchanger regulatory factor 2 represses colon cancer progress by suppression of Stat3 and CD24.The RACK1 signal anchor protein from Trypanosoma brucei associates with eukaryotic elongation factor 1A: a role for translational control in cytokinesis.Germline PTPRD mutations in Ewing sarcoma: biologic and clinical implications.The role of the insulin-like growth factor 1 receptor axis in multiple myeloma.E-cadherin cell-cell adhesion in ewing tumor cells mediates suppression of anoikis through activation of the ErbB4 tyrosine kinase.Inputs and outputs of insulin receptor.Novel function of MDA-9/Syntenin (SDCBP) as a regulator of survival and stemness in glioma stem cells.Cross-talk between the insulin-like growth factor (IGF) axis and membrane integrins to regulate cell physiology.RACK1, a versatile hub in cancer.Blocking the road, stopping the engine or killing the driver? Advances in targeting EWS/FLI-1 fusion in Ewing sarcoma as novel therapy.Co-delivery of insulin-like growth factor 1 receptor specific siRNA and doxorubicin using chitosan-based nanoparticles enhanced anticancer efficacy in A549 lung cancer cell line.Snail-Modulated MicroRNA 493 Forms a Negative Feedback Loop with the Insulin-Like Growth Factor 1 Receptor Pathway and Blocks TumorigenesisMiR-7, inhibited indirectly by lincRNA HOTAIR, directly inhibits SETDB1 and reverses the EMT of breast cancer stem cells by downregulating the STAT3 pathway.Essential function for PDLIM2 in cell polarization in three-dimensional cultures by feedback regulation of the β1-integrin-RhoA signaling axis.Regulation of protein translation and c-Jun expression by prostate tumor overexpressed 1.Downregulation of receptor for activated C-kinase 1 (RACK1) suppresses tumor growth by inhibiting tumor cell proliferation and tumor-associated angiogenesis.Treatment of biliary tract cancer with NVP-AEW541: mechanisms of action and resistance.Phosphorylation of RACK1 on tyrosine 52 by c-Abl is required for insulin-like growth factor I-mediated regulation of focal adhesion kinase.Sustained Src inhibition results in signal transducer and activator of transcription 3 (STAT3) activation and cancer cell survival via altered Janus-activated kinase-STAT3 bindingBeta1 integrin adhesion enhances IL-6-mediated STAT3 signaling in myeloma cells: implications for microenvironment influence on tumor survival and proliferation
P2860
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P2860
RACK1 recruits STAT3 specifically to insulin and insulin-like growth factor 1 receptors for activation, which is important for regulating anchorage-independent growth.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
RACK1 recruits STAT3 specifica ...... anchorage-independent growth.
@ast
RACK1 recruits STAT3 specifica ...... anchorage-independent growth.
@en
RACK1 recruits STAT3 specifica ...... anchorage-independent growth.
@nl
type
label
RACK1 recruits STAT3 specifica ...... anchorage-independent growth.
@ast
RACK1 recruits STAT3 specifica ...... anchorage-independent growth.
@en
RACK1 recruits STAT3 specifica ...... anchorage-independent growth.
@nl
prefLabel
RACK1 recruits STAT3 specifica ...... anchorage-independent growth.
@ast
RACK1 recruits STAT3 specifica ...... anchorage-independent growth.
@en
RACK1 recruits STAT3 specifica ...... anchorage-independent growth.
@nl
P2093
P2860
P1476
RACK1 recruits STAT3 specifica ...... anchorage-independent growth.
@en
P2093
Cong S Zong
Lu-Hai Wang
Pablo Lopez-Bergami
Ulrich Hermanto
Weizhou Zhang
P2860
P304
P356
10.1128/MCB.26.2.413-424.2006
P407
P50
P577
2006-01-01T00:00:00Z