Identification of the novel splicing variants for the hPXR in human livers
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Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptorRole of pregnane X receptor in chemotherapeutic treatmentPXR variants: the impact on drug metabolism and therapeutic responsesHuman pregnane X receptor: genetic polymorphisms, alternative mRNA splice variants, and cytochrome P450 3A metabolic activityHuman pregnane X receptor is expressed in breast carcinomas, potential heterodimers formation between hPXR and RXR-alphaTissue-specific regulation of pregnane X receptor in cancer development and therapy.Drug-activated nuclear receptors CAR and PXR.Top Three Pharmacogenomics and Personalized Medicine Applications at the Nexus of Renal Pathophysiology and Cardiovascular Medicine.Metabolism and transport of oxazaphosphorines and the clinical implications.PXR and CAR: nuclear receptors which play a pivotal role in drug disposition and chemical toxicity.Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs.A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response.PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics.Human pregnane X receptor compromises the function of p53 and promotes malignant transformationThe major human pregnane X receptor (PXR) splice variant, PXR.2, exhibits significantly diminished ligand-activated transcriptional regulation.Identification of polymorphisms in the 3'-untranslated region of the human pregnane X receptor (PXR) gene associated with variability in cytochrome P450 3A (CYP3A) metabolism.The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism.Long-term virus-induced alterations of CYP3A-mediated drug metabolism: a look at the virology, immunology and molecular biology of a multi-faceted problem.Xenobiotic receptor humanized mice and their utility.CYP3A5 genotype did not impact on nifedipine disposition in healthy volunteers.A Genome-Wide Association Study Identifies a Candidate Gene Associated With Atazanavir Exposure Measured in Hair.Genetic variability of PXR in Saudi Arabians.
P2860
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P2860
Identification of the novel splicing variants for the hPXR in human livers
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Identification of the novel splicing variants for the hPXR in human livers
@ast
Identification of the novel splicing variants for the hPXR in human livers
@en
Identification of the novel splicing variants for the hPXR in human livers
@nl
type
label
Identification of the novel splicing variants for the hPXR in human livers
@ast
Identification of the novel splicing variants for the hPXR in human livers
@en
Identification of the novel splicing variants for the hPXR in human livers
@nl
prefLabel
Identification of the novel splicing variants for the hPXR in human livers
@ast
Identification of the novel splicing variants for the hPXR in human livers
@en
Identification of the novel splicing variants for the hPXR in human livers
@nl
P2093
P3181
P1476
Identification of the novel splicing variants for the hPXR in human livers
@en
P2093
Akihiko Sumida
Hideyasu Matsuda
Isamu Yamamoto
Junichi Azuma
Shuichi Fukuen
Tadanobu Inaba
Tsuyoshi Fukuda
P3181
P356
10.1016/S0006-291X(02)02469-5
P407
P577
2002-11-01T00:00:00Z