Puma is an essential mediator of p53-dependent and -independent apoptotic pathways - Wikidata - wikimedia - TriplyDB

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

http://www.wikidata.org/entity/Q28213279

about

sameAs

Hypoxia and defective apoptosis drive genomic instability and tumorigenesis CHK2 kinase expression is down-regulated due to promoter methylation in non-small cell lung cancer Glioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressor Expression of the Bcl-3 proto-oncogene suppresses p53 activation Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53 HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53 Chemical genomics identifies small-molecule MCL1 repressors and BCL-xL as a predictor of MCL1 dependency Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domains PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite Therapeutic efficacy of PUMA for malignant glioma cells regardless of p53 status.Suppression of tumorigenesis by the p53 target PUMA The Bcl-2 apoptotic switch in cancer development and therapy PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome PUMA, a potent killer with or without p53 Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation An Epstein-Barr virus-encoded microRNA targets PUMA to promote host cell survival The BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cells Sp1 and p73 activate PUMA following serum starvation The NF-kappaB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cells FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction p53 independent induction of PUMA mediates intestinal apoptosis in response to ischaemia-reperfusion Tumor suppressor p53 and its gain-of-function mutants in cancer The BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer Therapeutics How cell death shapes cancer The role of tumor suppressor p53 in the antioxidant defense and metabolism Periodic Exposure of Keratinocytes to Cold Physical Plasma: An In Vitro Model for Redox-Related Diseases of the Skin.PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells The p53 circuit board SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells SMAC/Diablo mediates the proapoptotic function of PUMA by regulating PUMA-induced mitochondrial events Quantitative proteomic analysis of myc-induced apoptosis: a direct role for Myc induction of the mitochondrial chloride ion channel, mtCLIC/CLIC4 Proteomic response to 5,6-dimethylxanthenone 4-acetic acid (DMXAA, vadimezan) in human non-small cell lung cancer A549 cells determined by the stable-isotope labeling by amino acids in cell culture (SILAC) approach Endogenously produced nitric oxide mitigates sensitivity of melanoma cells to cisplatin Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics Ccdc94 protects cells from ionizing radiation by inhibiting the expression of p53 Concomitant loss of proapoptotic BH3-only Bcl-2 antagonists Bik and Bim arrests spermatogenesis

P2860

Q22242660-C116E603-9E79-42F1-BF91-57BD75D90561 Q23919381-09D00E46-1C87-4ACF-9391-628BF40F9A35 Q24299628-DF11FB2A-5C37-4DBA-B3ED-002DB29B0DA7 Q24300022-D786746F-AE42-4A35-BC75-42E8FBA508D5 Q24300781-9A33E4AF-9AB4-4A6E-B72A-103CF3E822C8 Q24301527-D66E93DF-D0D8-4AC9-8F02-719C2ABB8E3D Q24315549-4CFEA623-7255-4ACA-A772-7254CD9891AB Q24315623-0B417728-AD26-46BA-99CA-DCFD72B9D130 Q24316443-A6C3B6F5-6B27-42EE-8D04-1E4AA0DB9302 Q24534853-3438C530-40A3-4355-8E8E-B82ACC31F026 Q24542478-501A5C95-4D3C-47F4-8672-8240A1178B8A Q24563144-163C3410-0007-42DC-B3AD-2CBD529F3EE0 Q24620437-0EC6B533-CA71-48FD-98C9-1ADA9A632AB8 Q24627524-355B6F84-7CAC-4F7B-9C45-F72B1D59C8C2 Q24631776-2EC82EA3-033B-4A5D-9153-7D44368C0390 Q24643422-892229F3-49ED-42A9-B7AD-3D3C81899800 Q24649032-4B8C1F1D-2A4A-4481-B726-9F3A911DB091 Q24650702-CE4BF1E0-56C4-4AFF-8E05-B3EB9C81F344 Q24655353-07DF81B4-B4D4-4517-A005-3BD8E18DB9E0 Q24676636-8BD2C1FB-0385-4932-9320-40BB73AD6A80 Q24676637-E752818B-2180-47CC-AA05-3D6F75ECBE79 Q24677017-5202A98F-6639-4AA4-BA00-7AD66B78EB0A Q24681282-9B266721-A0FF-4A90-90DC-69A1C3569713 Q27000754-C8EFDA01-4652-4BC1-9B16-837DDBF6E7C3 Q27010154-CC4EAABA-C0EB-44E9-A909-C76AC059F2B9 Q27021441-18D6F50C-A3ED-41B1-986E-DE7F9C0BF20C Q27027604-03C75295-AD18-40B1-959E-4AFDA46484BC Q27348706-0D8890B2-5C65-4566-AEE7-67ED70E9FB37 Q27675952-8DF07DC8-161A-49B1-9687-B3F6E0B97A08 Q28247124-C9B3E839-9567-46A9-B5D3-6423BB71DD8C Q28255883-5B9B8F6B-36E4-4876-89F9-FB9B46B296D1 Q28259725-8B172CBA-D772-4591-88FB-DA84B9F5050F Q28264289-6692F4FB-438A-478A-BFC1-8F4248B9B952 Q28284206-A1C8A18A-A1EE-4392-BADD-5707CBA2AB7C Q28284332-A67F482F-D150-4FA5-AE78-70E73C400874 Q28388409-7DF3173D-8105-48FC-A470-976104423D1E Q28392262-DAE47DE6-CADE-45E8-87F6-0C2E609D833F Q28469345-A69A6391-1765-47F6-B22C-B236842A0F42 Q28483080-3901D8EE-6048-4E48-B1A9-7F01AC32C72D Q28511476-C2C08FBF-A3A8-491F-ADC9-D1F397C51176

P2860

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

http://www.wikidata.org/entity/Q28213279

description

2003 nî lūn-bûn

@nan

2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

@ast

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

@en

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

@nl

type

label

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

@ast

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

@en

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

@nl

prefLabel

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

@ast

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

@en

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

@nl

P1433

Q28213279-ED943973-3D74-4062-85CE-7E92761B4F1C

P1476

Q28213279-340A1D1C-AFBA-45B7-9C98-593BF5C2F701

P2093

Q28213279-0681CBBE-C631-4167-AD70-45909C2DF761

Q28213279-30CE4511-7990-45E4-89B2-25EF448D23AE

Q28213279-3C5DFCC3-A836-4B75-B27C-88B314E465A4

Q28213279-513D8816-95A7-47CB-BF11-B0FFDB202F4A

Q28213279-59C808CA-D057-4E8D-9546-BA3C87609C34

Q28213279-5C50F425-5EE4-4725-AAD3-2613264575AF

Q28213279-7F8ABFD0-FA2C-4967-B31A-1384BFE991D9

Q28213279-819A61AC-320E-45FF-BDE6-67669D0A2160

Q28213279-A94589BB-B5F9-47AC-B59E-9AB460E5A6A9

Q28213279-B49D8622-A11D-46E2-AFC0-09F86F077E3D

P304

Q28213279-75BB5A36-FD5D-4083-91C1-EFA307B43F0D

P31

Q28213279-DA3AA96F-DA46-4388-9332-42E7616DC64B

P3181

Q28213279-D4A10156-95B9-45C5-B7ED-52D7EB721C30

P356

Q28213279-7E4488CD-274F-40AF-A076-AE87403CDD3E

P407

Q28213279-6E1E43BA-A31D-43DD-BBF7-B7D84E5C9AC4

P433

Q28213279-11A04A9F-C7A5-41E5-BB25-C7A0A1A56B30

P478

Q28213279-9F02AC0F-7226-4AC9-93CF-078F430151AE

P577

Q28213279-E006BB2C-DF9E-411C-839E-14886B053686

P5875

Q28213279-98FD2432-3B4A-4EBC-AA6E-4A7D93AC9261

P698

Q28213279-1E631A08-9CF6-41A3-9A82-03563D26E4F2

P921

Q28213279-0B4BDBCE-23DF-4BE5-BB0A-3F3278CA3C1C

P3181

P356

S1535-6108(03)00244-7

P1433

P1476

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

@en

P2093

Chunying Yang

http://www.w3.org/2001/XMLSchema#string

Evan Parganas

http://www.w3.org/2001/XMLSchema#string

Gerard P Zambetti

http://www.w3.org/2001/XMLSchema#string

James N Ihle

http://www.w3.org/2001/XMLSchema#string

Jennifer Brennan

http://www.w3.org/2001/XMLSchema#string

Jiawen Han

http://www.w3.org/2001/XMLSchema#string

JinLing Wang

http://www.w3.org/2001/XMLSchema#string

John L Cleveland

http://www.w3.org/2001/XMLSchema#string

John R Jeffers

http://www.w3.org/2001/XMLSchema#string

Kirsteen H MacLean

http://www.w3.org/2001/XMLSchema#string

P304

321-8

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

261226

http://www.w3.org/2001/XMLSchema#string

P356

10.1016/S1535-6108(03)00244-7

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

4

http://www.w3.org/2001/XMLSchema#string

P577

2003-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

9035352

http://www.w3.org/2001/XMLSchema#string

P698

14585359

http://www.w3.org/2001/XMLSchema#string

P921

apoptotic process