Characterization of the physical interaction of Gli proteins with SUFU proteins - Wikidata - wikimedia - TriplyDB

Characterization of the physical interaction of Gli proteins with SUFU proteins

Characterization of the physical interaction of Gli proteins with SUFU proteins

http://www.wikidata.org/entity/Q28214496

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Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function A potential role of alternative splicing in the regulation of the transcriptional activity of human GLI2 in gonadal tissues.Structural basis of SUFU-GLI interaction in human Hedgehog signalling regulation.Identification of the gene transcription repressor domain of Gli3 Inhibition of GLI1 gene activation by Patched1 Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci Mice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic development The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins Regulatory role for Krüppel-like zinc-finger protein Gli-similar 1 (Glis1) in PMA-treated and psoriatic epidermis.MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription Suppressor of fused regulates Gli activity through a dual binding mechanism The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal domain of human Sufu The zebrafish mutants dre, uki, and lep encode negative regulators of the hedgehog signaling pathway.MicroRNAs in liver fibrosis: Focusing on the interaction with hedgehog signaling Cilia functions in development Crosstalk between Wnt/β-catenin and Hedgehog/Gli signaling pathways in colon cancer and implications for therapy Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma Computational prediction and experimental verification of new MAP kinase docking sites and substrates including Gli transcription factors Novel mechanism of action on Hedgehog signaling by a suppressor of fused carboxy terminal variant Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway GLIS3, a novel member of the GLIS subfamily of Krüppel-like zinc finger proteins with repressor and activation functions Intraflagellar transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts Coordinated translocation of mammalian Gli proteins and suppressor of fused to the primary cilium Hedgehog signaling downregulates suppressor of fused through the HIB/SPOP-Crn axis in Drosophila.beta-Strand interactions at the domain interface critical for the stability of human lens gammaD-crystallin Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors.Semi-quantitative evaluation of CD44(+) /CD24(-) tumor cell distribution in breast cancer tissue using a newly developed fluorescence immunohistochemical staining method.Identification of a novel ZIC3 isoform and mutation screening in patients with heterotaxy and congenital heart disease Zebrafish miR-214 modulates Hedgehog signaling to specify muscle cell fate.The transcriptional repressor domain of Gli3 is intrinsically disordered Modulation of the transactivation function and stability of Krüppel-like zinc finger protein Gli-similar 3 (Glis3) by Suppressor of Fused.Reconstruction of the gene regulatory network involved in the sonic hedgehog pathway with a potential role in early development of the mouse brain Multisite interaction with Sufu regulates Ci/Gli activity through distinct mechanisms in Hh signal transduction.Ormeloxifene suppresses desmoplasia and enhances sensitivity of gemcitabine in pancreatic cancer A Comparison of Ci/Gli Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog Response Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1 Ciliary Entry of the Hedgehog Transcriptional Activator Gli2 Is Mediated by the Nuclear Import Machinery but Differs from Nuclear Transport in Being Imp-α/β1-Independent Tumor-Derived Suppressor of Fused Mutations Reveal Hedgehog Pathway Interactions.

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Characterization of the physical interaction of Gli proteins with SUFU proteins

http://www.wikidata.org/entity/Q28214496

description

2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

article publié dans la revue scientifique Journal of Biological Chemistry

@fr

artículu científicu espublizáu en 2003

@ast

im Februar 2003 veröffentlichter wissenschaftlicher Artikel

@de

scientific article (publication date: 14 February 2003)

@en

vedecký článok (publikovaný 2003/02/14)

@sk

vědecký článek publikovaný v roce 2003

@cs

wetenschappelijk artikel (gepubliceerd op 2003/02/14)

@nl

наукова стаття, опублікована в лютому 2003

@uk

name

Characterization of the physical interaction of Gli proteins with SUFU proteins

@ast

Characterization of the physical interaction of Gli proteins with SUFU proteins

@en

Characterization of the physical interaction of Gli proteins with SUFU proteins

@nl

type

label

Characterization of the physical interaction of Gli proteins with SUFU proteins

@ast

Characterization of the physical interaction of Gli proteins with SUFU proteins

@en

Characterization of the physical interaction of Gli proteins with SUFU proteins

@nl

prefLabel

Characterization of the physical interaction of Gli proteins with SUFU proteins

@ast

Characterization of the physical interaction of Gli proteins with SUFU proteins

@en

Characterization of the physical interaction of Gli proteins with SUFU proteins

@nl

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Characterization of the physical interaction of Gli proteins with SUFU proteins

@en

P2093

Marina Dunaeva

http://www.w3.org/2001/XMLSchema#string

Piret Michelson

http://www.w3.org/2001/XMLSchema#string

Priit Kogerman

http://www.w3.org/2001/XMLSchema#string

Rune Toftgard

http://www.w3.org/2001/XMLSchema#string

P2860

Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3

Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1

GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity

Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1

Identification of an amplified, highly expressed gene in a human glioma

Suppressor of fused negatively regulates beta-catenin signaling

Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1

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5116-22

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2506023

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10.1074/JBC.M209492200

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