Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
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Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XLThe 44 kDa Pim-1 kinase directly interacts with tyrosine kinase Etk/BMX and protects human prostate cancer cells from apoptosis induced by chemotherapeutic drugsPIM-1 kinase interacts with the DNA binding domain of the vitamin D receptor: a further kinase implicated in 1,25-(OH)2D3 signalingPIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancersPim1 kinase synergizes with c-MYC to induce advanced prostate carcinomaEnhancement of myocardial regeneration through genetic engineering of cardiac progenitor cells expressing Pim-1 kinaseInsertional mutagenesis reveals progression genes and checkpoints in MYC/Runx2 lymphomasCryptic promoter activity in the DNA sequence corresponding to the pim-1 5'-UTRAssociation of Nuclear PIM1 Expression with Lymph Node Metastasis and Poor Prognosis in Patients with Lung Adenocarcinoma and Squamous Cell CarcinomaTargeting Pim kinases for cancer treatment: opportunities and challengesThe PIM kinases in hematological cancersThe p53 circuit boardPIM1 kinase as a target for cancer therapyThe oncogenic serine/threonine kinase Pim-1 phosphorylates and inhibits the activity of Cdc25C-associated kinase 1 (C-TAK1): a novel role for Pim-1 at the G2/M cell cycle checkpointConditional transgenic expression of PIM1 kinase in prostate induces inflammation-dependent neoplasiaThe role of PIM1/PIM2 kinases in tumors of the male reproductive systemPIM-1 kinase expression in adipocytic neoplasms: diagnostic and biological implications.Ki67 and PIM1 expression predict outcome in mantle cell lymphoma treated with high dose therapy, stem cell transplantation and rituximab: a Cancer and Leukemia Group B 59909 correlative science studyA human functional protein interaction network and its application to cancer data analysisPim1 promotes human prostate cancer cell tumorigenicity and c-MYC transcriptional activity.Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes.RNAi screen identifies a synthetic lethal interaction between PIM1 overexpression and PLK1 inhibitionPathophysiological roles of Pim-3 kinase in pancreatic cancer development and progression.Cell and gene therapy for severe heart failure patients: the time and place for Pim-1 kinase.Regulation of Skp2 levels by the Pim-1 protein kinasePreservation of myocardial structure is enhanced by pim-1 engineering of bone marrow cellsHuman cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair.Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002.Pim-1 knockdown potentiates paclitaxel-induced apoptosis in human hormone-refractory prostate cancers through inhibition of NHEJ DNA repair.Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival.Cardiac progenitor cell cycling stimulated by pim-1 kinaseRegulation of CDK4EBNA3C augments Pim-1 mediated phosphorylation and degradation of p21 to promote B-cell proliferationScreening of cell cycle fusion proteins to identify kinase signaling networksInitial testing (stage 1) of SGI-1776, a PIM1 kinase inhibitor, by the pediatric preclinical testing program.PIM kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer cellsInecalcitol, an analog of 1α,25(OH)(2) D(3) , induces growth arrest of androgen-dependent prostate cancer cells.Autocrine release of interleukin-9 promotes Jak3-dependent survival of ALK+ anaplastic large-cell lymphoma cells.Differential regulation of androgen receptor by PIM-1 kinases via phosphorylation-dependent recruitment of distinct ubiquitin E3 ligases.Increased mitotic rate coincident with transient telomere lengthening resulting from pim-1 overexpression in cardiac progenitor cells.
P2860
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P2860
Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
@ast
Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
@en
Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
@nl
type
label
Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
@ast
Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
@en
Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
@nl
prefLabel
Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
@ast
Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
@en
Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
@nl
P2093
P3181
P1476
Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
@en
P2093
John Sedivy
Nancy S Magnuson
Nandini Bhattacharya
Philip F Mixter
Zeping Wang
P3181
P356
10.1016/S0167-4889(02)00347-6
P407
P577
2002-12-16T00:00:00Z