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MDM4 (MDMX) overexpression enhances stabilization of stress-induced p53 and promotes apoptosisDNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.p53 Acetylation: Regulation and ConsequencesBeta-arrestin 2 functions as a G-protein-coupled receptor-activated regulator of oncoprotein Mdm2MDM2 and MDMX: Alone and together in regulation of p53Functional activation of mutant p53V172F by platinum analogs in cisplatin-resistant human tumor cells is dependent on serine-20 phosphorylationp53 ubiquitination: Mdm2 and beyondMisfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer.MDM4 (MDMX) and its Transcript Variants.Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damageThe p53 orchestra: Mdm2 and Mdmx set the toneMdm2 RING mutation enhances p53 transcriptional activity and p53-p300 interaction.JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation.Gene and protein analysis reveals that p53 pathway is functionally inactivated in cytogenetically normal Acute Myeloid Leukemia and Acute Promyelocytic LeukemiaAmplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity.Drug-dependent functionalization of wild-type and mutant p53 in cisplatin-resistant human ovarian tumor cellsFunctions of MDMX in the modulation of the p53-response.Regulation of p53: a collaboration between Mdm2 and Mdmx.MDMX (MDM4), a Promising Target for p53 Reactivation Therapy and Beyond.Aggregation and Prion-Like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion Disease?The Transactivation Domains of the p53 Protein.Telomere attrition induces a DNA double-strand break damage signal that reactivates p53 transcription in HTLV-I leukemic cells.The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting and functional recovery after CNS injury.Inactivation of the MDM2 RING domain enhances p53 transcriptional activity in mice.Potential therapeutic targets of TP53 gene in the context of its classically canonical functions and its latest non-canonical functions in human cancer.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
MDMX inhibits the p300/CBP-mediated acetylation of p53
@ast
MDMX inhibits the p300/CBP-mediated acetylation of p53
@en
MDMX inhibits the p300/CBP-mediated acetylation of p53
@nl
type
label
MDMX inhibits the p300/CBP-mediated acetylation of p53
@ast
MDMX inhibits the p300/CBP-mediated acetylation of p53
@en
MDMX inhibits the p300/CBP-mediated acetylation of p53
@nl
prefLabel
MDMX inhibits the p300/CBP-mediated acetylation of p53
@ast
MDMX inhibits the p300/CBP-mediated acetylation of p53
@en
MDMX inhibits the p300/CBP-mediated acetylation of p53
@nl
P1433
P1476
MDMX inhibits the p300/CBP-mediated acetylation of p53
@en
P2093
Frank McCormick
Peter Sabbatini
P304
P356
10.1089/104454902320219077
P407
P577
2002-07-01T00:00:00Z