Identification of UNC119 as a novel activator of SRC-type tyrosine kinases
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Unc119, a novel activator of Lck/Fyn, is essential for T cell activationThe B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85UNC119a bridges the transmission of Fyn signals to Rab11, leading to the completion of cytokinesisRIBEYE recruits Munc119, a mammalian ortholog of the Caenorhabditis elegans protein unc119, to synaptic ribbons of photoreceptor synapsesUnc119 protects from Shigella infection by inhibiting the Abl family kinasesC5orf30 is a negative regulator of tissue damage in rheumatoid arthritisTbUNC119 and its binding protein complex are essential for propagation, motility, and morphogenesis of Trypanosoma brucei procyclic form cells.Synaptic transmission at retinal ribbon synapsesNormal T-cell development and immune functions in TRIM-deficient mice.Contribution of Crk adaptor proteins to host cell and bacteria interactions.Functional characterization of a competitive peptide antagonist of p65 in human macrophage-like cells suggests therapeutic potential for chronic inflammation.A mutation in the human Uncoordinated 119 gene impairs TCR signaling and is associated with CD4 lymphopenia.Highly expressed UNC119 promotes hepatocellular carcinoma cell proliferation through Wnt/β-catenin signaling and predicts a poor prognosisUncoordinated (UNC)119: coordinating the trafficking of myristoylated proteins.The signaling mechanism of eosinophil activation.Consequences of a mutation in the UNC119 gene for T cell function in idiopathic CD4 lymphopenia.The role of membrane rafts in Lck transport, regulation and signalling in T-cells.Spatial cycles mediated by UNC119 solubilisation maintain Src family kinases plasma membrane localisation.Novel Biochemical and Structural Insights into the Interaction of Myristoylated Cargo with Unc119 Protein and Their Release by Arl2/3.Small-Molecule Inhibition of the UNC119-Cargo Interaction.Intrinsic properties and plasma membrane trafficking route of Src family kinase SH4 domains sensitive to retargeting by HIV-1 Nef.Differential regulation of interleukin 5-stimulated signaling pathways by dynamin.The Ciliary Machinery Is Repurposed for T Cell Immune Synapse Trafficking of LCKUNC119 is a binding partner of tumor suppressor Ras-association domain family 6 and induces apoptosis and cell cycle arrest by MDM2 and p53
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P2860
Identification of UNC119 as a novel activator of SRC-type tyrosine kinases
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2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
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2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Identification of UNC119 as a novel activator of SRC-type tyrosine kinases
@ast
Identification of UNC119 as a novel activator of SRC-type tyrosine kinases
@en
Identification of UNC119 as a novel activator of SRC-type tyrosine kinases
@nl
type
label
Identification of UNC119 as a novel activator of SRC-type tyrosine kinases
@ast
Identification of UNC119 as a novel activator of SRC-type tyrosine kinases
@en
Identification of UNC119 as a novel activator of SRC-type tyrosine kinases
@nl
prefLabel
Identification of UNC119 as a novel activator of SRC-type tyrosine kinases
@ast
Identification of UNC119 as a novel activator of SRC-type tyrosine kinases
@en
Identification of UNC119 as a novel activator of SRC-type tyrosine kinases
@nl
P2093
P2860
P356
P1476
Identification of UNC119 as a novel activator of SRC-type tyrosine kinases
@en
P2093
Magdalena M Gorska
Rafeul Alam
Sanjiv Sur
Susan J Stafford
P2860
P304
P356
10.1074/JBC.M208261200
P407
P577
2003-03-07T00:00:00Z