Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells
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Lysophosphatidic acid production and action: critical new players in breast cancer initiation and progressionL-histidine inhibits production of lysophosphatidic acid by the tumor-associated cytokine, autotaxinThe emerging role of FTY720 (Fingolimod) in cancer treatmentRole of the autotaxin-lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapyp100 Deficiency is insufficient for full activation of the alternative NF-κB pathway: TNF cooperates with p52-RelB in target gene transcriptionATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation.Structural basis for specific inhibition of Autotaxin by a DNA aptamerLysophosphatidate induces chemo-resistance by releasing breast cancer cells from taxol-induced mitotic arrestAn essential oligomannosidic glycan chain in the catalytic domain of autotaxin, a secreted lysophospholipase-DTemporal linkage between the phenotypic and genomic responses to caloric restrictionInhibition of autotaxin production or activity blocks lysophosphatidylcholine-induced migration of human breast cancer and melanoma cellsalpha- and beta-substituted phosphonate analogs of LPA as autotaxin inhibitorsCancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclastsDetection of gene pathways with predictive power for breast cancer prognosis.Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targetsAutotaxin signaling via lysophosphatidic acid receptors contributes to vascular endothelial growth factor-induced endothelial cell migration.LPA receptor signaling: pharmacology, physiology, and pathophysiology.NFAT proteins: emerging roles in cancer progression.Requirement of Osteopontin in the migration and protection against Taxol-induced apoptosis via the ATX-LPA axis in SGC7901 cells.Stat3 mediates expression of autotaxin in breast cancerATX-LPA receptor axis in inflammation and cancer.Activation of fibroblast-like synoviocytes derived from rheumatoid arthritis via lysophosphatidic acid-lysophosphatidic acid receptor 1 cascadeLigand-based autotaxin pharmacophore models reflect structure-based docking results.Autotaxin overexpression causes embryonic lethality and vascular defectsc-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomasThe autotaxin-lysophosphatidic acid-lysophosphatidic acid receptor cascade: proposal of a novel potential therapeutic target for treating glioblastoma multiformeThe autotaxin-LPA2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair.Reduced expression of autotaxin predicts survival in uveal melanoma.Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasisPositive feedback between vascular endothelial growth factor-A and autotaxin in ovarian cancer cellsGlobal and targeted metabolomics of esophageal squamous cell carcinoma discovers potential diagnostic and therapeutic biomarkersAutotaxin (ATX): a multi-functional and multi-modular protein possessing enzymatic lysoPLD activity and matricellular propertiesAutocrine factors that sustain glioma invasion and paracrine biology in the brain microenvironment.Autotaxin Inhibition with PF-8380 Enhances the Radiosensitivity of Human and Murine Glioblastoma Cell LinesAssessment of the antitumor potential of Bithionol in vivo using a xenograft model of ovarian cancer.Hits of a high-throughput screen identify the hydrophobic pocket of autotaxin/lysophospholipase D as an inhibitory surface.Roles of LPA in ovarian cancer development and progression.Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer.The role and therapeutic potential of the autotaxin-lysophosphatidate signalling axis in breast cancer.Lysophosphatidic acid as a lipid mediator with multiple biological actions.
P2860
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P2860
Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells
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2002 nî lūn-bûn
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2002 թուականին հրատարակուած գիտական յօդուած
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2002 թվականին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
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name
Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells
@ast
Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells
@en
Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells
@nl
type
label
Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells
@ast
Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells
@en
Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells
@nl
prefLabel
Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells
@ast
Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells
@en
Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells
@nl
P2093
P3181
P356
P1476
Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells
@en
P2093
Chang Gyo Park
Hoi Young Lee
Hyang Woo Lee
Hyun Cheol Chung
Jangsoon Lee
Jeung Whan Han
Seong Ki Min
Seonghwan Kim
So Young Yang
Sungyoul Hong
P2888
P3181
P356
10.1023/A:1020950420196
P407
P577
2002-01-01T00:00:00Z
P6179
1036781136