Hits of a high-throughput screen identify the hydrophobic pocket of autotaxin/lysophospholipase D as an inhibitory surface.
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Autotaxin: structure-function and signalingTargeting the hydrophobic pocket of autotaxin with virtual screening of inhibitors identifies a common aromatic sulfonamide structural motif.Interaction of platelet-derived autotaxin with tumor integrin αVβ3 controls metastasis of breast cancer cells to bone.Autotaxin, a lysophospholipase D with pleomorphic effects in oncogenesis and cancer progressionChemical modulation of glycerolipid signaling and metabolic pathways.The role and therapeutic potential of the autotaxin-lysophosphatidate signalling axis in breast cancer.Promising pharmacological directions in the world of lysophosphatidic Acid signaling.Autotaxin inhibitors: a patent review (2012-2016).Discovery and synthetic optimization of a novel scaffold for hydrophobic tunnel-targeted autotaxin inhibition.
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Hits of a high-throughput screen identify the hydrophobic pocket of autotaxin/lysophospholipase D as an inhibitory surface.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 21 June 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Hits of a high-throughput scre ...... se D as an inhibitory surface.
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Hits of a high-throughput scre ...... se D as an inhibitory surface.
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type
label
Hits of a high-throughput scre ...... se D as an inhibitory surface.
@en
Hits of a high-throughput scre ...... se D as an inhibitory surface.
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prefLabel
Hits of a high-throughput scre ...... se D as an inhibitory surface.
@en
Hits of a high-throughput scre ...... se D as an inhibitory surface.
@nl
P2093
P2860
P356
P1476
Hits of a high-throughput scre ...... se D as an inhibitory surface.
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P2093
Abby L Parrill
Daniel L Baker
Derek D Norman
Duane D Miller
Gabor Tigyi
James I Fells
Jianxiong Liu
Keng Gat Lim
R Jason Kirby
Renukadevi Patil
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P304
P356
10.1124/MOL.113.087080
P577
2013-06-21T00:00:00Z