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Genome-wide association of lipid-lowering response to statins in combined study populationsLocalization of human equilibrative nucleoside transporters, hENT1 and hENT2, in renal epithelial cellsEvolutionary conservation predicts function of variants of the human organic cation transporter, OCT1The PsychENCODE projectCrowdsourcing biomedical research: leveraging communities as innovation enginesNucleoside transporters in the disposition and targeting of nucleoside analogs in the kidneyA statin-dependent QTL for GATM expression is associated with statin-induced myopathyPharmacogenomic discovery using cell-based modelsRHOA is a modulator of the cholesterol-lowering effects of statinDeveloping predictive molecular maps of human disease through community-based modelingCrowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancerHuman whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseasesCrowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder ChallengeOveractive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteinsCombined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatinFunctional and genetic diversity in the concentrative nucleoside transporter, CNT1, in human populations.The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics.Integrative modeling of eQTLs and cis-regulatory elements suggests mechanisms underlying cell type specificity of eQTLs.Changes in atherogenic dyslipidemia induced by carbohydrate restriction in men are dependent on dietary protein sourcePrediction of human population responses to toxic compounds by a collaborative competition.Effects of dietary saturated fat on LDL subclasses and apolipoprotein CIII in menTranscriptome correlation analysis identifies two unique craniosynostosis subtypes associated with IRS1 activation.Pharmacogenomics of statin response.A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT.Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.Gene expression elucidates functional impact of polygenic risk for schizophrenia.HNRNPA1 regulates HMGCR alternative splicing and modulates cellular cholesterol metabolism.Sorting of rat SPNT in renal epithelium is independent of N-glycosylation.Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.Targeted metabolomics and medication classification data from participants in the ADNI1 cohort.PharmGKB very important pharmacogene: SLCO1B1.Transmembrane protein 55B is a novel regulator of cellular cholesterol metabolismMangravite et al. reply.Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate.Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment.Fatty acid desaturase regulation in adipose tissue by dietary composition is independent of weight loss and is correlated with the plasma triacylglycerol response.Democratizing Health Data for Translational Research.PharmGKB update: III. Genetic variants of SLC22A1, solute carrier family 22 (organic cation transporter), member 1.A community approach to mortality prediction in sepsis via gene expression analysis.
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description
hulumtuese
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onderzoeker
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researcher
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հետազոտող
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name
Lara M. Mangravite
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Lara M. Mangravite
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Lara M. Mangravite
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Lara M. Mangravite
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Lara M. Mangravite
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Lara M. Mangravite
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Lara M. Mangravite
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Lara M. Mangravite
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Lara M Mangravite
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Lara Mangravite
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Lara Mangravite
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Lara M. Mangravite
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Lara M. Mangravite
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Lara M. Mangravite
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Lara M. Mangravite
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P106
P1416
P21
P31
P496
0000-0001-7841-3612