Bile acids induce ectopic expression of intestinal guanylyl cyclase C Through nuclear factor-kappaB and Cdx2 in human esophageal cells
about
CDX2 expression is progressively decreased in human gastric intestinal metaplasia, dysplasia and cancerGuanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity.IkappaBalpha polymorphism at promoter region (rs2233408) influences the susceptibility of gastric cancer in Chinese.Bile acids initiate lineage-addicted gastroesophageal tumorigenesis by suppressing the EGF receptor-AKT axis.hTERT promotes gastric intestinal metaplasia by upregulating CDX2 via NF-κB signaling pathway.Glutathione Peroxidase 7 Suppresses Bile Salt-Induced Expression of Pro-Inflammatory Cytokines in Barrett's Carcinogenesis.Loss of glutathione peroxidase 7 promotes TNF-α-induced NF-κB activation in Barrett's carcinogenesis.Acid and bile salt-induced CDX2 expression differs in esophageal squamous cells from patients with and without Barrett's esophagus.The role of acid and bile reflux in oesophagitis and Barrett's metaplasiaModification of Helicobacter pylori Peptidoglycan Enhances NOD1 Activation and Promotes Cancer of the Stomach.Risk factors affecting the Barrett's metaplasia-dysplasia-neoplasia sequence.The rat kidney contains high levels of prouroguanylin (the uroguanylin precursor) but does not express GC-C (the enteric uroguanylin receptor).Acid, bile, and CDX: the ABCs of making Barrett's metaplasia.Barrett's esophagus: can biomarkers predict progression to malignancy?Single nucleotide polymorphisms of caudal type homeobox 1 and 2 are associated with Barrett's esophagus.Acidified bile acids enhance tumor progression and telomerase activity of gastric cancer in mice dependent on c-Myc expression.Systematic review: the role of bile acids in the pathogenesis of gastro-oesophageal reflux disease and related neoplasia.Molecular mechanisms of Barrett's esophagus.Immature myeloid progenitors promote disease progression in a mouse model of Barrett's-like metaplasia.In vitro model for gastroduodenal reflux-induced nuclear factor-kappaB activation and its role in hypopharyngeal carcinogenesis.Pulsatile exposure to simulated reflux leads to changes in gene expression in a 3D model of oesophageal mucosa.Notch signaling pathway and Cdx2 expression in the development of Barrett's esophagus.Transformation of benign Barrett's epithelium by repeated acid and bile exposure over 65 weeks: a novel in vitro model.Repeated exposure to acid and bile selectively induces colonic phenotype expression in a heterogeneous Barrett's epithelial cell line.Gastro-oesophageal reflux disease is associated with up-regulation of desmosomal components in oesophageal mucosa.Reduced expression of αGlcNAc in Barrett's oesophagus adjacent to Barrett's adenocarcinoma--a possible biomarker to predict the malignant potential of Barrett's oesophagus.[Barrett's esophagus: analyses from human and experimental animal studies].Transgenic Cdx2 induces endogenous Cdx1 in intestinal metaplasia of Cdx2-transgenic mouse stomach.Consistent expression of guanylyl cyclase-C in primary and metastatic gastrointestinal cancers.NF-κB is activated in oesophageal fibroblasts in response to a paracrine signal generated by acid-exposed primary oesophageal squamous cells.Ectopic expression of guanylyl cyclase C and endogenous ligand guanylin correlates significantly with Helicobacter pylori infection in gastric carcinogenesis.Chemoprevention of esophageal adenocarcinoma in a rat model by ursodeoxycholic acid
P2860
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P2860
Bile acids induce ectopic expression of intestinal guanylyl cyclase C Through nuclear factor-kappaB and Cdx2 in human esophageal cells
description
2006 nî lūn-bûn
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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Bile acids induce ectopic expr ...... Cdx2 in human esophageal cells
@ast
Bile acids induce ectopic expr ...... Cdx2 in human esophageal cells
@en
Bile acids induce ectopic expr ...... Cdx2 in human esophageal cells
@nl
type
label
Bile acids induce ectopic expr ...... Cdx2 in human esophageal cells
@ast
Bile acids induce ectopic expr ...... Cdx2 in human esophageal cells
@en
Bile acids induce ectopic expr ...... Cdx2 in human esophageal cells
@nl
prefLabel
Bile acids induce ectopic expr ...... Cdx2 in human esophageal cells
@ast
Bile acids induce ectopic expr ...... Cdx2 in human esophageal cells
@en
Bile acids induce ectopic expr ...... Cdx2 in human esophageal cells
@nl
P2093
P50
P1433
P1476
Bile acids induce ectopic expr ...... Cdx2 in human esophageal cells
@en
P2093
Claire Domon-Cell
Giovanni M Pitari
Inna Chervoneva
Juan P Palazzo
Matthew Witek
Stephanie Schulz
Tianru Jin
P304
P356
10.1053/J.GASTRO.2005.12.032
P407
P577
2006-04-01T00:00:00Z