Guanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity.
about
The emerging role of immunotherapy in colorectal cancerLineage-specific T-cell responses to cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease.Selective antigen-specific CD4(+) T-cell, but not CD8(+) T- or B-cell, tolerance corrupts cancer immunotherapy.Bile acids initiate lineage-addicted gastroesophageal tumorigenesis by suppressing the EGF receptor-AKT axis.Colorectal cancer immunotherapy.GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancerBacterial heat-stable enterotoxins: translation of pathogenic peptides into novel targeted diagnostics and therapeutics.Inactivated or live-attenuated bivalent vaccines that confer protection against rabies and Ebola viruses.A uroguanylin-GUCY2C endocrine axis regulates feeding in mice.Immunotherapeutic strategies to target prognostic and predictive markers of cancer.Cytokine adjuvanation of therapeutic anti-tumor immunity targeted to cancer mucosa antigens.Tumor radiation therapy creates therapeutic vaccine responses to the colorectal cancer antigen GUCY2C.GUCY2C-targeted cancer immunotherapy: past, present and future.Cure and curse: E. coli heat-stable enterotoxin and its receptor guanylyl cyclase CCANCER MUCOSA ANTIGENS A NOVEL PARADIGM IN CANCER IMMUNOTHERAPEUTICSGuanylate cyclase C as a target for prevention, detection, and therapy in colorectal cancer.Preclinical Evaluation of a Replication-Deficient Recombinant Adenovirus Serotype 5 Vaccine Expressing Guanylate Cyclase C and the PADRE T-helper Epitope.The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.Prime-Boost Immunization Eliminates Metastatic Colorectal Cancer by Producing High-Avidity Effector CD8+ T Cells.GUCY2C-directed CAR-T cells oppose colorectal cancer metastases without autoimmunity.The Heat-Stable Enterotoxin Receptor, Guanylyl Cyclase C, as a Pharmacological Target in Colorectal Cancer Immunotherapy: A Bench-to-Bedside Current Report.Epitope-targeted cytotoxic T cells mediate lineage-specific antitumor efficacy induced by the cancer mucosa antigen GUCY2C.A monomethyl auristatin E-conjugated antibody to guanylyl cyclase C is cytotoxic to target-expressing cells in vitro and in vivo.Trial watch: DNA-based vaccines for oncological indicationsNon-thermal plasma induces immunogenic cell death in murine CT26 colorectal tumorsCould targeting T-helper cells aid the development of effective cancer vaccines?
P2860
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P2860
Guanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Guanylyl cyclase C-induced imm ...... tastases without autoimmunity.
@ast
Guanylyl cyclase C-induced imm ...... tastases without autoimmunity.
@en
type
label
Guanylyl cyclase C-induced imm ...... tastases without autoimmunity.
@ast
Guanylyl cyclase C-induced imm ...... tastases without autoimmunity.
@en
prefLabel
Guanylyl cyclase C-induced imm ...... tastases without autoimmunity.
@ast
Guanylyl cyclase C-induced imm ...... tastases without autoimmunity.
@en
P2093
P2860
P50
P356
P1476
Guanylyl cyclase C-induced imm ...... tastases without autoimmunity.
@en
P2093
Benjamin J Stafford
Jay L Rothstein
Laurence C Eisenlohr
Mathew Thakur
Matthias J Schnell
Stephanie Schulz
P2860
P304
P356
10.1093/JNCI/DJN178
P407
P577
2008-06-24T00:00:00Z