Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci
about
Chemotherapy for children with medulloblastomaCombined MYC and P53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable diseaseDissecting the genomic complexity underlying medulloblastomaSignificance and therapeutic value of miRNAs in embryonal neural tumorsAdvances in managing medulloblastoma and intracranial primitive neuro-ectodermal tumorsCasein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis.MicroRNAs in pediatric central nervous system embryonal neoplasms: the known unknownDNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsiesInhibition of mTOR-kinase destabilizes MYCN and is a potential therapy for MYCN-dependent tumorsOutcome and prognostic factors of desmoplastic medulloblastoma treated within a multidisciplinary treatment concept.Radiation-induced adult medulloblastoma: a two-case report and review of the literature.Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort.Actionable molecular biomarkers in primary brain tumors.Joint binding of OTX2 and MYC in promotor regions is associated with high gene expression in medulloblastoma.Mutation and expression analysis in medulloblastoma yields prognostic variants and a putative mechanism of disease for i17q tumors.Diagnostic application of high resolution single nucleotide polymorphism array analysis for children with brain tumorsMolecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas.Genetic alterations in microRNAs in medulloblastomas.Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations.A microRNA-1280/JAG2 network comprises a novel biological target in high-risk medulloblastoma.Distinct genomic aberrations between low-grade and high-grade gliomas of Chinese patients.Homozygous loss of ADAM3A revealed by genome-wide analysis of pediatric high-grade glioma and diffuse intrinsic pontine gliomas.Predicting relapse in patients with medulloblastoma by integrating evidence from clinical and genomic features.Molecular subgroups of medulloblastoma.Large cell anaplastic medulloblastoma metastatic to the scalp: tumor and derived stem-like cells featuresMolecular and in vivo characterization of cancer-propagating cells derived from MYCN-dependent medulloblastomaTargeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.Establishment of a patient-derived orthotopic osteosarcoma mouse modelPrognostic classification of pediatric medulloblastoma based on chromosome 17p loss, expression of MYCC and MYCN, and Wnt pathway activation.Multiple mechanisms of MYCN dysregulation in Wilms tumour.An animal model of MYC-driven medulloblastomaClonal selection drives genetic divergence of metastatic medulloblastoma.Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samplesThe micro-RNA 199b-5p regulatory circuit involves Hes1, CD15, and epigenetic modifications in medulloblastoma.Myc proteins in brain tumor development and maintenance.MB3W1 is an orthotopic xenograft model for anaplastic medulloblastoma displaying cancer stem cell- and Group 3-propertiesPediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct.Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC.Novel cell lines established from pediatric brain tumors.Early recurrence in standard-risk medulloblastoma patients with the common idic(17)(p11.2) rearrangement
P2860
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P2860
Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Outcome prediction in pediatri ...... 17q and the MYC and MYCN loci
@ast
Outcome prediction in pediatri ...... 17q and the MYC and MYCN loci
@en
Outcome prediction in pediatri ...... 17q and the MYC and MYCN loci
@nl
type
label
Outcome prediction in pediatri ...... 17q and the MYC and MYCN loci
@ast
Outcome prediction in pediatri ...... 17q and the MYC and MYCN loci
@en
Outcome prediction in pediatri ...... 17q and the MYC and MYCN loci
@nl
prefLabel
Outcome prediction in pediatri ...... 17q and the MYC and MYCN loci
@ast
Outcome prediction in pediatri ...... 17q and the MYC and MYCN loci
@en
Outcome prediction in pediatri ...... 17q and the MYC and MYCN loci
@nl
P2093
P50
P3181
P356
P1476
Outcome prediction in pediatri ...... 17q and the MYC and MYCN loci
@en
P2093
Andrea Wittmann
Andreas Kulozik
Andrey Korshunov
Axel Benner
Frank Mendrzyk
Frauke Devens
Grischa Toedt
Nicolas U Gerber
Otmar D Wiestler
Stefan Joos
P304
P3181
P356
10.1200/JCO.2008.17.9432
P407
P577
2009-04-01T00:00:00Z