about
Dissecting the genomic complexity underlying medulloblastomaGenome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibitionOutcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN lociRole of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma.Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort.The transcription factor evi-1 is overexpressed, promotes proliferation, and is prognostically unfavorable in infratentorial ependymomas.Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas.Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma.New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs.DNA hypermethylation and aberrant expression of the EMP3 gene at 19q13.3 in Human Gliomas.Aberrant expression of retinoic acid signaling molecules influences patient survival in astrocytic gliomas.Prospective cohort study of radiotherapy with concomitant and adjuvant temozolomide chemotherapy for glioblastoma patients with no or minimal residual enhancing tumor load after surgeryChemotherapy for intracranial ependymoma in adultsRANK (TNFRSF11A) is epigenetically inactivated and induces apoptosis in gliomas.Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroupsMalignant astrocytomas of elderly patients lack favorable molecular markers: an analysis of the NOA-08 study collectiveBCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1.MiR-328 promotes glioma cell invasion via SFRP1-dependent Wnt-signaling activation.Limited role for extended maintenance temozolomide for newly diagnosed glioblastoma.Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing.Cordectomy as final treatment option for diffuse intramedullary malignant glioma using 5-ALA fluorescence-guided resection.Frequent epigenetic inactivation of the chaperone SGNE1/7B2 in human gliomas.Giant cell glioblastoma is associated with altered aurora b expression and concomitant p53 mutation.Epigenetic downregulation of mitogen-activated protein kinase phosphatase MKP-2 relieves its growth suppressive activity in glioma cells.Troglitazone-mediated sensitization to TRAIL-induced apoptosis is regulated by proteasome-dependent degradation of FLIP and ERK1/2-dependent phosphorylation of BAD.Molecular Diagnostics of Gliomas Using Next Generation Sequencing of a Glioma-Tailored Gene Panel.Gliomatosis cerebri: no evidence for a separate brain tumor entity.Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups.Septic-Metastasizing Aspergillus-Encephalitis Mimicking Massive Cerebral Infarction in a Heart Transplant Recipient: A Case Report.Prognostic significance of molecular markers and extent of resection in primary glioblastoma patients.NOA-05 phase 2 trial of procarbazine and lomustine therapy in gliomatosis cerebri.Optimization of quantitative MGMT promoter methylation analysis using pyrosequencing and combined bisulfite restriction analysis.Rapid and sensitive assessment of the IDH1 and IDH2 mutation status in cerebral gliomas based on DNA pyrosequencing.NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide.Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network.Comparison of (18)F-FET PET and 5-ALA fluorescence in cerebral gliomas.Gliomatosis cerebri: molecular pathology and clinical course.Predictive impact of MGMT promoter methylation in glioblastoma of the elderly.
P50
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P50
name
Jörg Felsberg
@ast
Jörg Felsberg
@en
Jörg Felsberg
@nl
type
label
Jörg Felsberg
@ast
Jörg Felsberg
@en
Jörg Felsberg
@nl
prefLabel
Jörg Felsberg
@ast
Jörg Felsberg
@en
Jörg Felsberg
@nl