Complete inhibition of anisomycin and UV radiation but not cytokine induced JNK and p38 activation by an aryl-substituted dihydropyrrolopyrazole quinoline and mixed lineage kinase 7 small interfering RNA

Complete inhibition of anisomycin and UV radiation but not cytokine induced JNK and p38 activation by an aryl-substituted dihydropyrrolopyrazole quinoline and mixed lineage kinase 7 small interfering RNA

Item

http://www.wikidata.org/entity/Q28237359

Q28237359

about

Lung inflammation caused by inhaled toxicants: a review Activation of cell stress response pathways by Shiga toxins Identification of small molecules that suppress ricin-induced stress-activated signaling pathways Marked small molecule libraries: a truncated approach to molecular probe design.Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation.The MAP kinase-activated protein kinase 2 (MK2) contributes to the Shiga toxin-induced inflammatory response ZAK is required for doxorubicin, a novel ribotoxic stressor, to induce SAPK activation and apoptosis in HaCaT cells.Morphine decreases bacterial phagocytosis by inhibiting actin polymerization through cAMP-, Rac-1-, and p38 MAPK-dependent mechanisms.Shiga toxin 2-induced intestinal pathology in infant rabbits is A-subunit dependent and responsive to the tyrosine kinase and potential ZAK inhibitor imatinib Phosphorylation of Atg5 by the Gadd45β-MEKK4-p38 pathway inhibits autophagy.Small molecule kinase inhibitors block the ZAK-dependent inflammatory effects of doxorubicin.BRAF inhibitors suppress apoptosis through off-target inhibition of JNK signaling.A Novel Zak Knockout Mouse with a Defective Ribotoxic Stress Response.A Requirement for ZAK Kinase Activity in Canonical TGF-β Signaling.A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles.Priming increases the anti-tumor effect and therapeutic window of 177Lu-octreotate in nude mice bearing human small intestine neuroendocrine tumor GOT1 Targeting kinases for the treatment of inflammatory diseases.Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients.Defining MAP3 kinases required for MDA-MB-231 cell tumor growth and metastasis.Discovery of LY2457546: a multi-targeted anti-angiogenic kinase inhibitor with a novel spectrum of activity and exquisite potency in the acute myelogenous leukemia-Flt-3-internal tandem duplication mutant human tumor xenograft model.ZAK: a MAP3Kinase that transduces Shiga toxin- and ricin-induced proinflammatory cytokine expression.Protein Synthesis Inhibition and Activation of the c-Jun N-Terminal Kinase Are Potential Contributors to Cisplatin Ototoxicity.The p38 SAPK is recruited to chromatin via its interaction with transcription factors A comprehensive target selectivity survey of the BCR-ABL kinase inhibitor INNO-406 by kinase profiling and chemical proteomics in chronic myeloid leukemia cells.Transient global cerebral ischemia induces up-regulation of MLTKα in hippocampal CA1 neurons.The MAP3K ZAK, a novel modulator of ERK-dependent migration, is upregulated in colorectal cancer.

P2860

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P2860

Complete inhibition of anisomycin and UV radiation but not cytokine induced JNK and p38 activation by an aryl-substituted dihydropyrrolopyrazole quinoline and mixed lineage kinase 7 small interfering RNA

Item

http://www.wikidata.org/entity/Q28237359

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2005 nî lūn-bûn

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2005 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2005 թվականի մայիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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