Genistein-mediated inhibition of glycosaminoglycan synthesis as a basis for gene expression-targeted isoflavone therapy for mucopolysaccharidoses
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Less Is More: Substrate Reduction Therapy for Lysosomal Storage DisordersGlycosaminoglycan remodeling during diabetes and the role of dietary factors in their modulationSanfilippo syndrome: causes, consequences, and treatmentsMorquio A syndrome: diagnosis and current and future therapiesNew therapeutic approaches for Krabbe disease: The potential of pharmacological chaperonesGenistein reduces glycosaminoglycan levels in a mouse model of mucopolysaccharidosis type IIThe phytoestrogen genistein modulates lysosomal metabolism and transcription factor EB (TFEB) activationGenistein improves neuropathology and corrects behaviour in a mouse model of neurodegenerative metabolic diseaseDietary Management of Skin Health: The Role of Genistein.Therapeutic approaches for lysosomal storage diseasesGene silencing of EXTL2 and EXTL3 as a substrate deprivation therapy for heparan sulphate storing mucopolysaccharidoses.Mucopolysaccharidosis type IIIB may predominantly present with an attenuated clinical phenotypeSubstrate deprivation therapy: a new hope for patients suffering from neuronopathic forms of inherited lysosomal storage diseases.Genistein-mediated inhibition of glycosaminoglycan synthesis, which corrects storage in cells of patients suffering from mucopolysaccharidoses, acts by influencing an epidermal growth factor-dependent pathway.Impairment of glycosaminoglycan synthesis in mucopolysaccharidosis type IIIA cells by using siRNA: a potential therapeutic approach for Sanfilippo disease.Effects of flavonoids on glycosaminoglycan synthesis: implications for substrate reduction therapy in Sanfilippo disease and other mucopolysaccharidoses.Cognitive development in patients with Mucopolysaccharidosis type III (Sanfilippo syndrome).Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids.Glycosaminoglycan storage disorders: a reviewEffects of flavonoids on expression of genes involved in cell cycle regulation and DNA replication in human fibroblastsActivities of genes controlling sphingolipid metabolism in human fibroblasts treated with flavonoids.Synthetic genistein derivatives as modulators of glycosaminoglycan storage.Glycosaminoglycans are involved in bacterial adherence to lung cells.The use of elevated doses of genistein-rich soy extract in the gene expression-targeted isoflavone therapy for Sanfilippo disease patients.Two-year follow-up of Sanfilippo Disease patients treated with a genistein-rich isoflavone extract: assessment of effects on cognitive functions and general status of patientsParents' experiences of living with, and caring for children, adolescents and young adults with Mucopolysaccharidosis (MPS).Coenzyme Q10 and Pyridoxal Phosphate Deficiency Is a Common Feature in Mucopolysaccharidosis Type III.Therapeutics based on stop codon readthrough.Nonsteroidal anti-inflammatory drugs modulate cellular glycosaminoglycan synthesis by affecting EGFR and PI3K signaling pathwaysTreating lysosomal storage diseases with pharmacological chaperones: from concept to clinics.Genistin-rich soy isoflavone extract in substrate reduction therapy for Sanfilippo syndrome: An open-label, pilot study in 10 pediatric patients.Pharmacological small molecules for the treatment of lysosomal storage disorders.Gene expression-targeted isoflavone therapy.Putative biological mechanisms of efficiency of substrate reduction therapies for mucopolysaccharidoses.Different Use of Cell Surface Glycosaminoglycans As Adherence Receptors to Corneal Cells by Gram Positive and Gram Negative PathogensThe renal Fanconi syndrome in cystinosis: pathogenic insights and therapeutic perspectives.Genistein increases glycosaminoglycan levels in mucopolysaccharidosis type I cell models.Small molecules as therapeutic agents for inborn errors of metabolism.Drug-Mediated Regulation of Glycosaminoglycan Biosynthesis.Mucopolysacccharidoses: From understanding to treatment, a century of discoveries.
P2860
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P2860
Genistein-mediated inhibition of glycosaminoglycan synthesis as a basis for gene expression-targeted isoflavone therapy for mucopolysaccharidoses
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Genistein-mediated inhibition ...... rapy for mucopolysaccharidoses
@ast
Genistein-mediated inhibition ...... rapy for mucopolysaccharidoses
@en
Genistein-mediated inhibition ...... rapy for mucopolysaccharidoses
@nl
type
label
Genistein-mediated inhibition ...... rapy for mucopolysaccharidoses
@ast
Genistein-mediated inhibition ...... rapy for mucopolysaccharidoses
@en
Genistein-mediated inhibition ...... rapy for mucopolysaccharidoses
@nl
prefLabel
Genistein-mediated inhibition ...... rapy for mucopolysaccharidoses
@ast
Genistein-mediated inhibition ...... rapy for mucopolysaccharidoses
@en
Genistein-mediated inhibition ...... rapy for mucopolysaccharidoses
@nl
P2093
P50
P3181
P356
P1476
Genistein-mediated inhibition ...... rapy for mucopolysaccharidoses
@en
P2093
Barbara Czartoryska
Ewa Piotrowska
Sylwia Barańska
P2888
P304
P3181
P356
10.1038/SJ.EJHG.5201623
P407
P577
2006-07-01T00:00:00Z