How enzymes work: analysis by modern rate theory and computer simulations
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Anatomy of enzyme channelsComputational enzyme design approaches with significant biological outcomes: progress and challengesCoarse-grained description of protein internal dynamics: an optimal strategy for decomposing proteins in rigid subunitsWeak, strong, and coherent regimes of Fröhlich condensation and their applications to terahertz medicine and quantum consciousnessCHARMM: the biomolecular simulation programEnzymes: An integrated view of structure, dynamics and functionBiomolecular electrostatics and solvation: a computational perspectiveAllosteric activation transitions in enzymes and biomolecular motors: insights from atomistic and coarse-grained simulationsEvolutionarily conserved linkage between enzyme fold, flexibility, and catalysisCircadian KaiC phosphorylation: a multi-layer networkCrystal structure of I-DmoI in complex with its target DNA provides new insights into meganuclease engineeringSnapshot of a Reaction Intermediate: Analysis of Benzoylformate Decarboxylase in Complex with a Benzoylphosphonate Inhibitor †Differential quantum tunneling contributions in nitroalkane oxidase catalyzed and the uncatalyzed proton transfer reactionStructural Evidence that Peroxiredoxin Catalytic Power Is Based on Transition-State StabilizationDynamics connect substrate recognition to catalysis in protein kinase ASequencing, biochemical characterization, crystal structure and molecular dynamics of cellobiohydrolase Cel7A from Geotrichum candidum 3CCapture of a third Mg²⁺ is essential for catalyzing DNA synthesisThe importance of ensemble averaging in enzyme kineticsMathematical and computational modeling in biology at multiple scalesEnzymatic transition states, transition-state analogs, dynamics, thermodynamics, and lifetimesMolecular dynamics and protein function.De novo enzyme design using Rosetta3Ternary composite of hemin, gold nanoparticles and graphene for highly efficient decomposition of hydrogen peroxideA Two-Metal-Ion-Mediated Conformational Switching Pathway for HDV Ribozyme ActivationDevelopment of Multiscale Models for Complex Chemical Systems: From H+H2to Biomolecules (Nobel Lecture)Intrinsic dynamics of an enzyme underlies catalysisLinking protein structure and dynamics to catalysis: the role of hydrogen tunnelling.Computational approaches for rational design of proteins with novel functionalitiesqPIPSA: relating enzymatic kinetic parameters and interaction fields.The dynamical nature of enzymatic catalysis.Computational identification of slow conformational fluctuations in proteinsIncorporating modeling and simulations in undergraduate biophysical chemistry course to promote understanding of structure-dynamics-function relationships in proteins.Convergent Mechanistic Features between the Structurally Diverse N- and O-Methyltransferases: Glycine N-Methyltransferase and Catechol O-Methyltransferase.The promoting vibration in human heart lactate dehydrogenase is a preferred vibrational channelStudying the role of protein dynamics in an SN2 enzyme reaction using free-energy surfaces and solvent coordinates.The role of enzyme dynamics and tunnelling in catalysing hydride transfer: studies of distal mutants of dihydrofolate reductase.Effects of a distal mutation on active site chemistry.Enzymatic transition states and dynamic motion in barrier crossing.Single-molecule enzymatic conformational dynamics: spilling out the product molecules.Electrostatic transition state stabilization rather than reactant destabilization provides the chemical basis for efficient chorismate mutase catalysis.
P2860
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P2860
How enzymes work: analysis by modern rate theory and computer simulations
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
How enzymes work: analysis by modern rate theory and computer simulations
@ast
How enzymes work: analysis by modern rate theory and computer simulations
@en
How enzymes work: analysis by modern rate theory and computer simulations
@nl
type
label
How enzymes work: analysis by modern rate theory and computer simulations
@ast
How enzymes work: analysis by modern rate theory and computer simulations
@en
How enzymes work: analysis by modern rate theory and computer simulations
@nl
prefLabel
How enzymes work: analysis by modern rate theory and computer simulations
@ast
How enzymes work: analysis by modern rate theory and computer simulations
@en
How enzymes work: analysis by modern rate theory and computer simulations
@nl
P3181
P356
P1433
P1476
How enzymes work: analysis by modern rate theory and computer simulations
@en
P2093
Mireia Garcia-Viloca
P304
P3181
P356
10.1126/SCIENCE.1088172
P407
P577
2004-01-09T00:00:00Z