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On side-chain conformational entropy of proteinsActivation of nanoscale allosteric protein domain motion revealed by neutron spin echo spectroscopyEfficient coupling of catalysis and dynamics in the E1 component of Escherichia coli pyruvate dehydrogenase multienzyme complexDifferential substrate specificity and kinetic behavior of Escherichia coli YfdW and Oxalobacter formigenes formyl coenzyme A transferaseInhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agentScale-free flow of life: on the biology, economics, and physics of the cellFunctional taxonomy of bacterial hyperstructuresEnzymes: An integrated view of structure, dynamics and functionAntibody Binding Modulates Conformational Exchange in Domain III of Dengue Virus E ProteinPerspectives on electrostatics and conformational motions in enzyme catalysisA model for cofactor use during HIV-1 reverse transcription and nuclear entryConformational selection in protein binding and functionComputer aided enzyme design and catalytic conceptsSynergistic applications of MD and NMR for the study of biological systemsAllosteric activation transitions in enzymes and biomolecular motors: insights from atomistic and coarse-grained simulationsStructure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocationEvolutionarily conserved linkage between enzyme fold, flexibility, and catalysisCorresponding functional dynamics across the Hsp90 Chaperone family: insights from a multiscale analysis of MD simulationsAccurate Determination of Conformational Transitions in Oligomeric Membrane Proteins.Modeling signal propagation mechanisms and ligand-based conformational dynamics of the Hsp90 molecular chaperone full-length dimerDiscovering conformational sub-states relevant to protein functionStructure of the N-terminal domain of a type B1 G protein-coupled receptor in complex with a peptide ligandDomain Orientation in the Inactive Response Regulator Mycobacterium tuberculosis MtrA Provides a Barrier to Activation † , ‡Ensemble Refinement of Protein Crystal Structures: Validation and ApplicationSolution Structure of Inhibitor-Free Human Metalloelastase (MMP-12) Indicates an Internal Conformational AdjustmentNMR and X-ray analysis of structural additivity in metal binding site-swapped hybrids of rubredoxinStructural, Biochemical, and in Vivo Characterization of the First Virally Encoded Cyclophilin from the MimivirusRecognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solutionAn Allosteric Circuit in Caspase-1Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selectionSolution Structure and Backbone Dynamics of Streptopain: INSIGHT INTO DIVERSE SUBSTRATE SPECIFICITYMultiple Conformers in Active Site of Human Dihydrofolate Reductase F31R/Q35E Double Mutant Suggest Structural Basis for Methotrexate ResistanceA Correspondence Between Solution-State Dynamics of an Individual Protein and the Sequence and Conformational Diversity of its FamilyThe prolyl isomerase domain of PpiD fromEscherichia colishows a parvulin fold but is devoid of catalytic activityHidden alternative structures of proline isomerase essential for catalysisConformational sampling, catalysis, and evolution of the bacterial phosphotriesteraseA Structural Element within the HUWE1 HECT Domain Modulates Self-ubiquitination and Substrate Ubiquitination ActivitiesConformational selection in the molten globule state of the nuclear coactivator binding domain of CBPRegulation of Response Regulator Autophosphorylation through Interdomain ContactsCoupling of receptor conformation and ligand orientation determine graded activity
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Intrinsic dynamics of an enzyme underlies catalysis
@ast
Intrinsic dynamics of an enzyme underlies catalysis
@en
type
label
Intrinsic dynamics of an enzyme underlies catalysis
@ast
Intrinsic dynamics of an enzyme underlies catalysis
@en
prefLabel
Intrinsic dynamics of an enzyme underlies catalysis
@ast
Intrinsic dynamics of an enzyme underlies catalysis
@en
P2093
P2860
P3181
P356
P1433
P1476
Intrinsic dynamics of an enzyme underlies catalysis
@en
P2093
Daryl A Bosco
Dmitry M Korzhnev
Dorothee Kern
Elan Z Eisenmesser
Jack J Skalicky
Lewis E Kay
Magnus Wolf-Watz
P2860
P2888
P304
P3181
P356
10.1038/NATURE04105
P407
P577
2005-11-01T00:00:00Z
P5875
P6179
1019275455